Post biopsy cavity treatment implants and methods

• US 7,780,948 B2
• Filed: 10/23/2008
• Issued: 08/24/2010
• Est. Priority Date: 07/25/2003
• Status: Expired due to Fees

• Current Assignee: Encapsule Medical, LLC
• Original Assignee: Rubicor Medical, LLC
• Inventors: Chernomorsky, Simon, Vetter, James W., Chernomorsky, Ary S.
• Primary Examiner(s): Henley, III; Raymond J
• Application Number:
  US12/256,619
• Publication Number:
  US 20090263442A1
• Time in Patent Office: 670 Days
• Field of Search: 424/1.37, 424/9.3, 424/600, 424/423
• US Class Current: 424/1.37
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00654 entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 2090/3987 Applicators for implanting markers
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61K 49/04 X-ray contrast preparations
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.

Claims

1. A method of treating a bodily cavity created by a procedure carried out through an incision and an access path defined between the incision and the cavity, comprising the steps of:

providing a post-procedure cavity implant, the post-procedure cavity implant including a material that is swellable when placed in a biological fluid environment, the provided post-procedure implant initially defining a pre-implantation state that enables the post-procedure implant to be implanted within the cavity through the access path;

implanting the post-procedure cavity implant into the cavity through the incision and through the access path, and

closing the incision, wherein the implanted post-procedure cavity implant swells within the biological fluid environment of the cavity to a post-implantation state in which the implant no longer fits through the access path.

2. The method of claim 1, wherein the providing step is carried out with the pre-implantation state being a compressed state and wherein the post-implantation state is a relatively uncompressed state.

3. The method of claim 1, wherein the providing step is carried out with the pre-implantation state being a folded state and wherein the post-implantation state is a comparatively at least partially unfolded state.

4. The method of claim 1, wherein the providing step is carried out with the pre-implantation state being an at least partially rolled up state and wherein the post-implantation state is a comparatively at least partially unrolled state.

5. The method of claim 1, wherein the providing step is carried out with the pre-implantation state defining a first shape and wherein the post-implantation state defines a second shape that is different from the first shape.

6. The method of claim 1, wherein the providing step is carried out with the post-procedure cavity implant being configured with a signaturing capability, in which a recognizable feature appears within the implant when imaged under predetermined imaging modality.

7. The method of claim 6, wherein the recognizable feature is formed or molded within a structure of the post-procedure cavity implant.

8. The method of claim 1, wherein the post-procedure cavity implant includes collagen.

9. The method of claim 6, wherein the providing step is carried out with the post-procedure cavity implant including at least one of an echogenic and radiopaque element and wherein the signaturing capability is embodied within the at least one of the radiopaque and radiopaque element.

10. The method of claim 6, wherein the providing step is carried out with the post-procedure cavity implant including a biocompatibly-sealed integrated circuit that is configured to be electronically interrogated.