Method for segmenting anatomical structures from 3D image data by using topological information

• US 7,783,091 B2
• Filed: 09/08/2005
• Issued: 08/24/2010
• Est. Priority Date: 09/09/2004
• Status: Expired due to Fees

• Current Assignee: Siemens Healthcare GMBH (Siemens AG)
• Original Assignee: Siemens AG
• Inventors: Rinck, Daniel, Scheuering, Michael
• Primary Examiner(s): Mehta; Bhavesh M
• Assistant Examiner(s): Rush; Eric
• Application Number:
  US11/220,665
• Publication Number:
  US 20060056694A1
• Time in Patent Office: 1,811 Days
• Field of Search: 382/100, 382128-132, 382/154, 382/173, 382/254
• US Class Current: 382/128
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/20101 Interactive definition of point of interest, landmark or seed
• CPC Class Codes: G06T 2207/30101 Blood vessel; Artery; Vein; Vascular
• CPC Class Codes: G06T 7/11 Region-based segmentation

Abstract

A method is disclosed for segmenting anatomical structures, in particular the coronary vessel tree, from 3D image data. In the method, a starting point is initially set in the 3D image data, and at least one known anatomically significant point and/or at least one known anatomically significant surface are/is identified in the 3D image data. Subsequently, proceeding from the starting point the structure is subsequently segmented pixel by pixel with the aid of a multiplicity of segmentation steps in such a way that an instantaneous distance is determined automatically relative to the anatomically significant point and/or to the anatomically significant surface in each segmentation step. Further, segmentation parameters and/or a selection of adjacent pixels for continuing the segmentation are/is established as a function of the distance, taking account of a model topology. The method enables an accurate and reliable segmentation of the anatomical structure.

Claims

1. A method for segmenting anatomical structures from 3D image data, the method comprising:

setting a starting point in the 3D image data;

identifying at least one of at least one known anatomically significant point and at least one known anatomically significant surface in the 3D image data;

segmenting, proceeding from the starting point, the anatomical structure pixel by pixel with a multiplicity of segmentation steps such that an instantaneous distance is determined automatically relative to at least one of the at least one known anatomically significant point and to the at least one known anatomically significant surface in each segmentation step;

establishing at least one of segmentation parameters and a selection of adjacent pixels for continuing the segmentation as a function of the determined distance, taking account of a model topology; and

displaying a result of the segmentation process,

wherein when a truncation point during the segmentation process is reached at a position at which the anatomical structure should not be truncated, based on the model topology, a search algorithm searches for pixels and continues the segmentation of the anatomical structure in an image region determined by an extrapolation of the already segmented anatomical structure, and

wherein a gap in the segmented anatomical structure is filled up by means of interpolation.

2. The method as claimed in claim 1, wherein before the start of segmenting the anatomical structure, at least one distance array is set up proceeding from the at least one known anatomically significant point, or the at least one known anatomically significant surface and is assigned to the pixels, at least one of the instantaneous distance relative to the at least one known anatomically significant point and the at least one known anatomically significant surface being determined directly from the distance array for each pixel during the segmentation process.

3. The method as claimed in claim 1, wherein the segmentation parameters are established for each segmentation step by recourse to a table in which respectively prescribed segmentation parameters are assigned to the different distances relative to at least one of the at least one known anatomically significant point and the at least one known anatomically significant surface.

4. The method as claimed in claim 1, wherein the selection of adjacent pixels for continuing the segmentation process is established for each segmentation step by recourse to a table in which in each case at least one prescribed segmentation directions are assigned to the different distances relative to at least one of the at least one known anatomically significant point and the at least one known anatomically significant surface in order to continue the segmentation process.

5. The method as claimed in claim 1, wherein tangential vectors of the already segmented anatomical structure are calculated in the region of the truncation point for the extrapolation.

6. The method as claimed in claim 5, wherein in order to detect pixels for continuing the anatomical structure a smoothness condition must be satisfied between the tangential vectors of the already segmented anatomical structure and tangential vectors of the continued structure in the region of the truncation point.

7. The method as claimed in claim 1, wherein when segmenting a coronary vessel tree from 3D image data of a heart the starting point is set in the aorta, and the apex and a geometrical centroid of the heart is identified in the 3D data as the at least one known anatomically significant point.

8. The method as claimed in claim 1, wherein when segmenting a coronary vessel tree from 3D image data of a heart the starting point is set in the aorta and a surface of the heart chambers that has been segmented in advance is identified in the 3D image data as the at least one known anatomically significant surface.

9. The method of claim 1, wherein the method is for segmenting a coronary vessel tree.

14. The method as claimed in claim 2, wherein the segmentation parameters are established for each segmentation step by recourse to a table in which respectively prescribed segmentation parameters are assigned to the different distances relative to at least one of the at least one known anatomically significant point and the at least one known anatomically significant surface.

15. The method as claimed in claim 2, wherein the selection of adjacent pixels for continuing the segmentation process is established for each segmentation step by recourse to a table in which in each case at least one prescribed segmentation directions are assigned to the different distances relative to at least one of the at least one known anatomically significant point and the at least one known anatomically significant surface in order to continue the segmentation process.

16. The method as claimed in claim 3, wherein the selection of adjacent pixels for continuing the segmentation process is established for each segmentation step by recourse to a table in which in each case at least one prescribed segmentation directions are assigned to the different distances relative to at least one of the at least one known anatomically significant point and the at least one known anatomically significant surface in order to continue the segmentation process.

17. The method as claimed in claim 1, wherein the 3D image data is generated in a Computed Tomography (CT) angiography.

10. A method for segmenting anatomical structures from a starting point in 3D image data, the method comprising:

identifying at least one of at least one known anatomically significant point and at least one known anatomically significant surface in the 3D image data;

determining a distance relative to at least one of the at least one known anatomically significant point and to the at least one known anatomically significant surface in each of a plurality of segmentations, the plurality of segmentations proceeding pixel by pixel from the starting point;

establishing at least one of segmentation parameters and a selection of adjacent pixels for continuing the segmentation process, at least partially as a function of the determined distance; and

displaying a result of the segmentation process,

wherein when a truncation point during the segmentation process is reached at a position at which the anatomical structure should not be truncated, based on a model topology, a search algorithm searches for pixels and continues the segmentation of the anatomical structure in an image region determined by an extrapolation of the already segmented anatomical structure, and

wherein a gap in the segmented anatomical structure is filled up by means of interpolation.

11. The method of claim 10, wherein the method is for segmenting a coronary vessel tree.

12. The method as claimed in claim 10, wherein before the start of segmenting the anatomical structure, at least one distance array is set up proceeding from the at least one known anatomically significant point, or the at least one known anatomically significant surface and is assigned to the pixels, at least one of the instantaneous distance relative to the at least one known anatomically significant point and the at least one known anatomically significant surface being determined directly from the distance array for each pixel during the segmentation process.

13. The method as claimed in claim 10, wherein the segmentation parameters are established for each segmentation step by recourse to a table in which respectively prescribed segmentation parameters are assigned to the different distances relative to at least one of the at least one known anatomically significant point and the at least one known anatomically significant surface.

18. The method as claimed in claim 10, wherein the 3D image data is generated in a Computed Tomography (CT) angiography.