Devices and methods using an implantable pulse generator for brain stimulation
First Claim
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1. A method for brain stimulation, the method comprising:
- inserting a lead into a cranium of a patient, the lead comprising at least one stimulation electrode disposed along a longitudinal surface of the lead; and
at least one recording electrode, separate from the at least one stimulation electrode, disposed on the lead;
inserting a stylet into the lead to assist in inserting the lead into the cranium of the patient;
identifying target neurons using the at least one recording electrode;
rotating the stylet to rotate the lead and assist in identifying the target neurons;
implanting a pulse generator in the patient; and
stimulating the target neurons using the at least one stimulation electrode and the implanted pulse generator.
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Abstract
A device for brain stimulation includes a lead having a longitudinal surface; at least one stimulation electrode disposed along the longitudinal surface of the lead; at least one recording electrode, separate from the at least one stimulation electrode, disposed on the lead; and an implantable pulse generator coupled to the at least one stimulation electrode. In some instances, the implantable pulse generator can be implanted into a burr hole in the skull made for insertion of the lead into the brain.
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Citations
21 Claims
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1. A method for brain stimulation, the method comprising:
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inserting a lead into a cranium of a patient, the lead comprising at least one stimulation electrode disposed along a longitudinal surface of the lead; and
at least one recording electrode, separate from the at least one stimulation electrode, disposed on the lead;inserting a stylet into the lead to assist in inserting the lead into the cranium of the patient; identifying target neurons using the at least one recording electrode; rotating the stylet to rotate the lead and assist in identifying the target neurons; implanting a pulse generator in the patient; and stimulating the target neurons using the at least one stimulation electrode and the implanted pulse generator. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method for brain stimulation, the method comprising:
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inserting a stylet into a lead to assist in inserting the lead into a cranium of a patient, the lead comprising a plurality of stimulation electrodes disposed along a longitudinal surface of the lead; and
at least one recording electrode, separate from the plurality of stimulation electrodes, disposed along the longitudinal surface of the lead, wherein at least one of the at least one recording electrodes is disposed between two of the plurality of stimulation electrodes, wherein the lead defines a lumen having a non-circular lateral cross-section extending longitudinally through at least a portion of the lead and the stylet has a corresponding lateral cross-section;inserting the lead and stylet into the cranium of the patient; identifying target neurons using the at least one recording electrode; stimulating the target neurons using at least one of the plurality of stimulation electrodes; and rotating the lead using the stylet, after identifying the target neurons, to align at least one of the plurality of stimulation electrodes with the target neurons. - View Dependent Claims (14, 15, 16, 17, 18, 19)
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20. A method for brain stimulation, the method comprising:
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inserting a lead into a cranium of a patient, the lead comprising at least one stimulation electrode disposed along a longitudinal surface of the lead; and
at least one recording electrode, separate from the at least one stimulation electrode, disposed on the lead;inserting a stylet into the lead to assist in inserting the lead into the cranium of the patient; identifying target neurons using the at least one recording electrode; rotating the stylet to rotate the lead and assist in identifying the target neurons; implanting a pulse generator in the patient; and stimulating the target neurons using the at least one stimulation electrode and the implanted pulse generator, wherein each recording electrode consists essentially of an exposed tip of a wire. - View Dependent Claims (21)
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Specification