Tissue treatment system

• US 7,785,322 B2
• Filed: 02/16/2006
• Issued: 08/31/2010
• Est. Priority Date: 02/22/2000
• Status: Expired due to Fees

• Current Assignee: Energist Limited
• Original Assignee: Plasmogen, Inc.
• Inventors: Goble, Colin Charles Owen, Goble, Nigel Mark, Penny, Keith
• Primary Examiner(s): Dvorak; Linda C
• Assistant Examiner(s): LEE, BENJAMIN HYOUNGSOL
• Application Number:
  US11/354,880
• Publication Number:
  US 20060189974A1
• Time in Patent Office: 1,657 Days
• Field of Search: 606 32- 52
• US Class Current: 606/34
• CPC Class Codes: A61B 18/042 using additional gas becoming plasma
• CPC Class Codes: A61B 2017/00725 Calibration or performance testing

Abstract

A tissue treatment system has a radio frequency generator and a handheld treatment instrument that generates a gas plasma jet for delivering thermal energy to a tissue surface to be treated. Incorporated in the housing for the generator is a calibration device for adjusting the energy output of the generator, if necessary, at the beginning of a treatment session. The calibration device has a target element with a target surface, a transducer for sensing changes in temperature of the target element with respect to the temperature of a reference element, and an energy output adjuster for adjusting the radio frequency energy output of the generator in response to a calibration signal generated by the transducer. The generator housing has a receptacle for locating the nozzle of the handheld instrument in juxtaposition with the target element so that when a plasma burst is generated as part of a calibration sequence it is incident on the target surface. The generator output is automatically adjusted to compensate for any deviation of a calibration value, produced from the calibration signal, from a reference value. Also disclosed is a method of regenerating the reticular architecture of tissue, the method including calibrating the energy delivery of a tissue treatment system.

Claims

1. A tissue treatment system comprising:

a radio frequency (r.f.) generator;

a treatment instrument connectible to the generator and to a source of ionisable gas and operable to produce a plasma jet at a nozzle of the instrument when supplied with the ionisable gas and energised by the generator; and

a calibration device that comprises;

a target element having a target surface area;

a transducer arranged to produce an electrical signal indicative of a temperature change of the target element within the target surface area;

a receptacle for locating the nozzle of the instrument in juxtaposition with the target surface area whereby, in operation of the instrument when the nozzle is in the receptacle, the plasma jet is incident upon the target surface area to cause the transducer to generate a calibration signal for adjusting the energy output of the generator; and

an output connected to the generator for coupling the calibration signal to the generator;

wherein the generator includes an energy output adjuster for adjusting the r.f. energy output of the generator, the adjuster being configured to adjust the r.f. energy output in response to the calibration signal.

2. A system according to claim 1, wherein the adjuster forms part of a controller which is configured to perform an automatic calibration process in which the generator is operated to feed a predetermined r.f. energy waveform to the instrument to cause generation of a calibrated plasma jet directed at the target surface area of the calibration device, the calibration signal generated as a result of the calibrated jet heating the target element is processed to produce a calibration value which is then compared with a reference value, and the adjuster is operated automatically in response to a deviation of the calibration value from the reference value to set the r.f. energy output for subsequent operation of the system.

3. A system according to claim 2, wherein the predetermined r.f. energy waveform comprises a plurality of pulses of r.f. energy.

4. A system according to claim 3, wherein the calibration value is a function combining the levels of successive pulses which are generated by the transducer and correspond to the pulses of r.f. energy.

5. A system according to claim 1, wherein the target element is a metallic plate and the transducer is in contact with the plate.

6. A system according to claim 5, wherein the transducer has an area greater than the cross-sectional area of the plasma jet when the instrument is operated in its calibration location.

7. A system according to claim 6, wherein the transducer comprises a plurality of temperature sensitive elements distributed in an array.

8. A system according to claim 1, wherein the transducer is arranged to produce an electrical signal representative of a difference in temperature between first and second elements of the transducer.

9. A system according to claim 1, wherein the transducer has a measurement surface and a reference surface, which surfaces are spaced apart, and wherein the transducer is operable to produce an electrical signal which is substantially linearly related to the difference between a temperature sensed at the measurement surface and a temperature sensed simultaneously at the reference surface.

10. A system according to claim 1, wherein the target element comprises a first transducer element, wherein the calibration device has a second transducer element spaced from the first transducer element, and wherein the system is arranged to perform a calibration process during which the temperature existing at the first transducer element is compared with the temperature existing at the second transducer element to produce the electrical signal.

11. A system according to claim 1, wherein the calibration device comprises a calorimeter having a metallic plate forming the target element, a heat sink portion underlying the metallic plate, and a temperature difference sensor located between the metallic plate and the heat sink portion and arranged to produce an electrical output signal indicative of the difference in temperature between the metallic plate and the heat sink portion.

12. A system according to claim 11, wherein the sensor comprises a Peltier device.

13. A system according to claim 1, wherein the generator is operable in a calibration mode to cause a burst of r.f. energy to be delivered to the instrument with a predetermined waveform and duration so as to cause the instrument, when supplied with the ionisable gas, to generate a calibration plasma jet, and wherein the calibration device is arranged automatically to evaluate the electrical signal produced when the calibration plasma jet is incident on the target surface area to generate an adjustment signal for adjusting the energy output of the generator.

14. A system according to claim 13, wherein the calibration device is arranged to evaluate the level of the electrical signal at a predetermined time after commencement of the burst of r.f. energy.

15. A system according to claim 13, wherein the generator is operable to produce the burst as a plurality of pulses and the calibration device is arranged to evaluate the level of the electrical signal after the application of a predetermined number of pulses.

16. A system according to claim 13, wherein the transducer is a temperature difference sensor and the calibration device is arranged to evaluate the level of the electrical signal when it reaches a maximum level.

17. A system according to claim 13, wherein the generator is operable to produce the burst as a succession of pulses, the transducer is a temperature difference sensor, and the calibration device is arranged to evaluate the level of the electrical signal when it reaches a peak level associated with the nth pulse occurring in the succession of pulses, n being a predetermined integer.

18. A system according to claim 1, wherein:

the generator is contained within a generator housing to which the treatment instrument is coupled by a cable for conveying r.f. energy from the generator to the instrument;

the calibration device is in the generator housing and has an associated instrument holder which opens out on a front section of the housing for receiving the instrument and which is shaped to locate the instrument longitudinally and transversely with respect to the target element.

19. A method of calibrating a tissue treatment system which includes a radio frequency (r.f.) generator, a treatment instrument connected to the generator and to a source of ionisable gas, and a calibration device comprising a target element and a temperature sensing transducer, a receptacle for locating a nozzle of the instrument in juxtaposition with a target surface area of the target element at a pre-defined location with respect thereto, and an output coupled to the generator, wherein the method comprises:

placing the treatment instrument in the receptacle;

causing gas to be supplied to the instrument and simultaneously causing a burst of r.f. energy to be delivered to the instrument with a predetermined waveform and duration so as to generate a plasma jet exiting the nozzle and incident upon the target element;

automatically evaluating a calibration signal generated by the calibration device at the output and representative of an output of the transducer resulting from heating of the target element by the plasma jet; and

setting the r.f. energy output level of the generator according to the evaluation of the calibration signal.