Plaque characterization using multiple intravascular ultrasound datasets having distinct filter bands

• US 7,789,834 B2
• Filed: 03/21/2007
• Issued: 09/07/2010
• Est. Priority Date: 03/21/2007
• Status: Active Grant

• Current Assignee: Volcano Corporation (Koninklijke Philips N.V.)
• Original Assignee: Volcano Corporation (Koninklijke Philips N.V.)
• Inventors: Margolis, Marja Paulina, Vince, David Geoffrey, Waters, Kendall Rand, Nair, Anuja
• Primary Examiner(s): Le; Long V
• Assistant Examiner(s): HOFFA, ANGELA MARIE
• Application Number:
  US11/689,327
• Publication Number:
  US 20080234582A1
• Time in Patent Office: 1,266 Days
• Field of Search: None
• US Class Current: 600/443
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 8/085 for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4488 the transducer being a phased array
• CPC Class Codes: A61B 8/461 Displaying means of special interest
• CPC Class Codes: A61B 8/5207 involving processing of raw data to produce diagnostic data, e.g. for generating an image reconstruction G06T11/00
• CPC Class Codes: G01S 15/8956 using frequencies at or above 20 MHz
• CPC Class Codes: G01S 7/52036 using analysis of echo signal for target characterisation

Abstract

A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.

Claims

1. A method of characterizing tissue, comprising:

collecting ultrasound echo information from a portion of an imaged body;

applying a first filter, having a relatively narrow first filter band, to a near range portion of the ultrasound echo information to render near range filtered echo information;

applying a first characterization criterion to the near range filtered echo information to render a near range tissue characterization image;

applying a second filter, having a relatively broad second filter band such that the second filter band is broader than and completely covers a frequency range of the first filter band, to a far range portion of the ultrasound echo information to render far range filtered echo information; and

applying a second characterization criterion to the far range filtered echo information to render a far range tissue characterization image.

2. The method of claim 1 wherein the first and second characterization criteria include frequency and power response characteristics of the near and far range filtered echo information.

3. The method of claim 1 wherein the tissue is vascular tissue.

4. The method of claim 3 wherein the tissue comprises plaque.

5. The method of claim 1 wherein the first filter band is about 12 to 26 MHz.

6. The method of claim 1 wherein the ultrasound echo information is rendered from a 20 MHz transducer.

7. The method of claim 1 wherein the ultrasound echo information is rendered from a 45 MHz transducer.

8. The method of claim 1 further comprising combining the near range and the far range tissue characterization image information to render a single displayable image.

9. The method of claim 1 further comprising applying a third filter and applying a third characterization criterion to at least a third range of echo information to render a third range tissue characterization image.

10. The method of claim 1 wherein the first and second filters are implemented by a single filter capable of applying multiple/variable filter bands.

11. A non-transitory computer-readable medium including computer-executable instructions facilitating characterizing tissue, the computer-executable instructions facilitating performing a set of steps comprising:

receiving ultrasound echo information associated with a portion of an imaged body;

applying a first filter, having a relatively narrow first filter band, to a near range portion of the ultrasound echo information to render near range filtered echo information;

applying a first characterization criterion to the near range filtered echo information to render a near range tissue characterization image;

applying a second filter, having a relatively broad second filter band such that the second filter band is broader than and completely covers a frequency range of the first filter band, to a far range portion of the ultrasound echo information to render far range filtered echo information; and

applying a second characterization criterion to the far range filtered echo information to render a far range tissue characterization image.

12. The computer-readable medium of claim 11 wherein the first and second characterization criteria include frequency and power response characteristics of the near and far range filtered echo information.

13. The computer-readable medium of claim 11 wherein the tissue is vascular tissue.

14. The computer-readable medium of claim 13 wherein the tissue comprises plaque.

15. The computer-readable medium of claim 11 further comprising combining the near range and the far range tissue characterization image information to render a single displayable image.

16. The computer-readable medium of claim 11 wherein the first and second filters are implemented by a single filter capable of applying multiple/variable filter bands.

17. A system for generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body, comprising:

a first filter, having a first filter band, configured to render near range filtered echo information from a near range portion of the ultrasound echo information;

a second filter, having a second filter band that completely covers and is broader than a frequency range of the first filter band, configured to render far range filtered echo information from a far range portion of the ultrasound echo information; and

a set of characterization criteria including;

a first characterization criterion configured to render a near range tissue characterization image from the near range filtered echo information, and

a second characterization criterion configured to render a far range tissue characterization image from the far range filtered echo information.

18. The system of claim 17 wherein the first and second characterization criteria include frequency and power response characteristics of the near and far range filtered echo information.

19. The system of claim 17 wherein the tissue is vascular tissue.

20. The system of claim 17 wherein the first filter band is about 12 to 26 MHz.

21. The system of claim 17 wherein the ultrasound echo information is rendered from a 20 MHz transducer.

22. The system of claim 17 wherein the ultrasound echo information is rendered from a 45 MHz transducer.

23. The system of claim 17 wherein the system further combines the near range and the far range tissue characterization image information to render a single displayable image.

24. The system of claim 17 further comprising at least one additional filter and characterization criterion that are applied to at least a third range of echo information to render a tissue characterization image corresponding to the third range.

25. The system of claim 17 wherein the first and second filters are implemented by a single filter capable of applying multiple/variable filter bands.