System for plasma-mediated thermo-electrical surgery

• US 7,789,879 B2
• Filed: 03/22/2007
• Issued: 09/07/2010
• Est. Priority Date: 05/03/2002
• Status: Expired due to Fees

• Current Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Original Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Inventors: Palanker, Daniel V., Vankov, Alexander B.
• Primary Examiner(s): Dvorak; Linda C
• Assistant Examiner(s): Scott; Amanda
• Application Number:
  US11/726,782
• Publication Number:
  US 20070239156A1
• Time in Patent Office: 1,265 Days
• Field of Search: 606/34, 606/37, 606 38- 42, 606 45- 50
• US Class Current: 606/42
• CPC Class Codes: A61B 18/042 using additional gas becoming plasma
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00601 Cutting
• CPC Class Codes: A61B 2018/00625 Vaporization
• CPC Class Codes: A61B 2018/1213 creating an arc
• CPC Class Codes: A61B 2018/122 ionizing, with corona
• CPC Class Codes: A61B 2018/1472 for use with liquid electrolyte, e.g. virtual electrodes
• CPC Class Codes: H05H 1/48 using an arc H05H1/26 takes precedence
• CPC Class Codes: H05H 2245/32 Surgery, e.g. scalpels, blades or bistoury; Treatments inside the body

Abstract

An apparatus and method for cutting a material including conducting and non-conducting materials such as biological tissue, cellulose or plastic while the material is submerged in a conductive liquid medium. The apparatus has a cutting electrode with an elongate cutting portion having an aspect ratio (length to width) of 1 or more and a return electrode. The two electrodes are immersed in the conductive medium and a voltage is applied between them to heat the medium, thus producing a vapor cavity around the elongate cutting portion and ionizing a gas inside the vapor cavity to produce a plasma. The voltage applied between the electrodes is modulated in pulses having a modulation format selected to minimize the size of the vapor cavity, its rate of formation and heat diffusion into the material while the latter is cut with an edge of the elongate cutting portion. The modulation format includes pulses ranging in duration from 10 μs to 10 ms, as well as minipulses and micropulses, as necessary. The apparatus and method of invention allow the user to perform efficient thermal ablation and electrosurgical procedures in particular at power levels as low as 10 mW with minimal thermal and cavitation damage.

Claims

1. A system for plasma-mediated thermo-electrical surgery comprising:

a cutting electrode having an elongate cutting portion having a length greater than its width, wherein the width is less than 250 μ

m;

a return electrode adapted to attach to the body of a patient remote from the cutting electrode; and

a voltage control unit coupled to the cutting electrode and configured to provide a plurality of voltage pulses to the cutting electrode, wherein the voltage control unit comprises;

a voltage source and

a pulse control configured to control the voltage applied to the cutting electrode from the voltage source, so that the voltage applied comprises a plurality of pulses each separated by an interval greater than 1 ms, wherein the duration of each pulse is between about 2 μ

s and 200 μ

s, and each pulse comprises a plurality of minipulses.

2. The system of claim 1, wherein the voltage control unit is further configured so that the minipulses are of alternating positive and negative polarities.

3. The system of claim 1, wherein the voltage control unit is further configured to vary a peak power of the minipulses.

4. The system of claim 1, wherein the voltage control unit is further configured so the duration of each minipulse is less than about 5 μ

sec.

5. The system of claim 1, further comprising a charge transfer prevention device coupled to the voltage control unit.

6. The system of claim 5, wherein the charge transfer prevention device comprises a capacitor.

7. The system of claim 1, further comprising a low impedance line electrically connecting the voltage control unit to the cutting electrode, whereby the low impedance line reflects the pulses.

8. The system of claim 1, further comprising a ballast resistor electrically connected between the cutting electrode and the voltage control unit.

9. The system of claim 1, wherein the elongate cutting portion has a width between about 1 μ

m and about 100 μ

m.

10. The system of claim 1, wherein the elongate cutting portion is circular in cross section.

11. The system of claim 1, wherein the elongate cutting portion defines at least one bend.

12. The system of claim 1, wherein the elongate cutting portion defines a loop.

13. The system of claim 1, wherein the cutting electrode comprises a wire electrode.

14. The system of claim 1, wherein the elongate cutting portion has a diameter between about 10 microns and about 200 microns and extends from an adjacent insulator by about 20 microns to about 1 mm, and wherein the insulator has a diameter between about 0.1 mm and about 1 mm, and wherein the elongate cutting portion has a bent tip.

15. The system of claim 1, wherein a ratio of the length to width of the cutting portion is larger than five.

16. The system of claim 1, wherein the pulse control comprises a peak power control and a duration control configured to adjust the duration of the pulses and the pulse interval.

17. The system of claim 1, wherein the duration of each pulse is about 0.1 ms.

18. A system for plasma-mediated thermo-electrical surgery comprising:

a cutting electrode having an elongate cutting portion having a length greater than its width, wherein the width is less than 250 μ

m;

a return electrode adapted to attach to the body of a patient remote from the cutting electrode; and

a voltage control unit coupled to the cutting electrode and configured to provide the cutting electrode with a plurality of pulses each separated by an interval of greater than 1 ms, and each of the pulses comprises a plurality of minipulses;

wherein the voltage control unit comprises

a voltage source, and

a pulse control having a duration control configured to adjust the duration of the pulses between about 2 μ

s and 200 μ

s, and further configured to adjust the interval between the minipulses.

19. A system for plasma-mediated thermo-electrical surgery comprising:

a cutting electrode having an elongate cutting portion having a length at least five times greater than its width, wherein the width is less than 100 μ

m;

a return electrode adapted to attach to the body of a patient remote from the cutting electrode; and

a voltage control unit coupled to the cutting electrode and configured to provide a plurality of pulses each separated by an interval greater than 1 ms, wherein the duration of each pulse is between about 2 μ

s and 200 μ

s, and each pulse comprises a plurality of minipulses each separated by an interval;

wherein the voltage control unit comprises;

a voltage source, and

a pulse control configured to produce vaporization and ionization at the cutting portion during each pulse, and to terminate plasma discharge between the pulses.