System and method for three-dimensional airway reconstruction, assessment and analysis

• US 7,794,399 B2
• Filed: 01/24/2006
• Issued: 09/14/2010
• Est. Priority Date: 01/24/2006
• Status: Active Grant

• Current Assignee: Ran Ben-David, Tamir Cohen
• Original Assignee: Ran Ben-David, Tamir Cohen
• Inventors: Singh, Gurdev Dave
• Primary Examiner(s): Mallari; Patricia C
• Application Number:
  US11/338,554
• Publication Number:
  US 20070173724A1
• Time in Patent Office: 1,694 Days
• Field of Search: 600/529, 600/437, 600/443
• US Class Current: 600/443
• CPC Class Codes: A61B 5/085 Measuring impedance of respiratory organs or lung elasticity
• CPC Class Codes: A61B 5/1075 for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer A61B8/0858 takes precedence
• CPC Class Codes: A61B 5/42 Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence

Abstract

This invention relates to a system and method for three-dimensional airway reconstruction, assessment and analysis. Specifically, the invention relates to a system and method for acquiring one- and two-dimensional data regarding a cavity, such as an esophagus or an airway, and manipulating that data to reconstruct a three-dimensional geometrical object representing that cavity. Suitable data collection methods include, but are not limited to, non-ionizing, non-invasive protocols including acoustic reflectometry, such as that performed by a DOS®- or Windows®-based pharyngometer or rhinometer. The resulting three-dimensional geometric object of the subject cavity can be used to diagnose cavity morphology/obstruction, aid in management and treatment of the obstruction, evaluate efficacy of management and treatment of the obstruction and also provide information for use in outcome analysis and forensic and medico-legal evaluation of diagnosis and treatment of cavity obstruction/stenosis.

Claims

1. A system comprising:

a processor configured to receive

cross-sectional data representative of cross-sectional areas of a cavity of an object being measured by an acoustic reflectometer at a plurality of distances from an origin point of the cavity, and

feature data representative of at least a portion of the anatomical features of the object; and

a storage unit configured to store a plurality of data files, the data files comprising the received cross-sectional data,

wherein the processor is programmed to create a three-dimensional graphical representation of the cavity by calculating a plurality of nodes based on the cross-sectional data, forming a plurality of circles based on the calculated nodes, rotating the plurality of circles in accordance with the feature data, and connecting the nodes following rotation of the plurality of circles to form a triangular mesh, and

the storage unit is configured to store the three-dimensional graphical representation.

2. The system of claim 1, further comprising a display unit to display the three-dimensional representation of the cavity.

3. The system of claim 1, wherein the object comprises a mammal.

4. The system of claim 3, wherein the object comprises a human being.

5. The system of claim 1, wherein the cavity comprises an airway.

6. The system of claim 1, wherein the acoustic reflectometer comprises one of a pharyngometer or a rhinometer.

7. The system of claim 1, wherein the processor is further programmed to manipulate the three-dimensional representation of the cavity to analyze the effect of a new condition of the cavity.

8. The system of claim 7, wherein the processor is further programmed to measure changes in size, changes in shape, and the directionality of changes to the cavity under a new condition.

9. The system of claim 1, wherein the processor is programmed to superimpose the three-dimensional representation of the cavity on a digital radiograph or digital photograph of the cavity.