System for measuring pulsatile vascular resistance
First Claim
1. A system for the analysis of arterial blood flow velocity measurements comprising means for receiving input signals delivered by an arterial blood flow velocity (FV) sensor and by an arterial blood pressure (BP) sensor, wherein said FV and BP signals are recorded simultaneously and continuously, further comprising means for processing and outputting signals, wherein said processing comprises:
- synchronization of both signals at start upstroke,a beat-to-beat analysis of the signals, whereby the pulsatile vascular resistance is calculated from the difference in relationship between FV and BP signals during systole compared to diastole.
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Abstract
The invention relates to acquiring information concerning the hemodynamic status of the brain (or any other organ) by measuring and analysing the pulsatile properties of blood flow (velocities) in the organ'"'"'s feeding vessels in relation to the pulsatile properties of the systemic arterial blood pressure. Provided is a system for the analysis of arterial blood flow velocity measurements, comprising means for receiving input signals delivered by an arterial blood flow velocity (FV) sensor and by an arterial blood pressure (BP) sensor, wherein said FV and BP signals are recorded simulataneously and continuously, further comprising means for processing and outputting signals, wherein said processing comprises calculating the pulsatile apparent resistance (PaR) or the Pulse Flow Velocity Mismatch (PFVM). Plotting PAR or PVFM against mean arterial blood pressure and/or end tidal CO2 levels can serve as an indicator for the effectiveness of imposed therapy.
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Citations
17 Claims
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1. A system for the analysis of arterial blood flow velocity measurements comprising means for receiving input signals delivered by an arterial blood flow velocity (FV) sensor and by an arterial blood pressure (BP) sensor, wherein said FV and BP signals are recorded simultaneously and continuously, further comprising means for processing and outputting signals, wherein said processing comprises:
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synchronization of both signals at start upstroke, a beat-to-beat analysis of the signals, whereby the pulsatile vascular resistance is calculated from the difference in relationship between FV and BP signals during systole compared to diastole. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. Method for determining pulsatile vascular resistance (PVR), preferably pulsatile vascular cerebrovascular resistance, said method comprising the steps of:
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recording an arterial blood flow velocity (FV) signal and an arterial blood pressure (BP) signal, wherein said FV and BP signals are recorded simultaneously and continuously; synchronizing said FV and BP signal at start-upstroke; optionally averaging said signals to avoid respiratory effects; and calculating with a processing device the pulsatile vascular resistance in a beat-to-beat analysis of the signals, from the difference in relationship between FV and BP signals during systole compared to diastole. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17)
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Specification