Multiple biopsy device

• US 7,794,409 B2
• Filed: 01/14/2005
• Issued: 09/14/2010
• Est. Priority Date: 04/05/2002
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Damarati, John Jairo
• Primary Examiner(s): Hindenburg; Max
• Assistant Examiner(s): Foreman; Jonathan M
• Application Number:
  US11/036,927
• Publication Number:
  US 20050124913A1
• Time in Patent Office: 2,069 Days
• Field of Search: 600104-107, 600/121, 600/123, 600/127, 600/129, 600/562, 600564-568, 604/22, 606/167, 606/170, 606/171
• US Class Current: 600/565
• CPC Class Codes: A61B 10/0266 means for severing sample
• CPC Class Codes: A61B 10/0275 with sample notch, e.g. on the side of inner stylet
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 2010/0225 for taking multiple samples
• CPC Class Codes: A61B 2017/00296 mounted on an endoscope
• CPC Class Codes: A61B 2017/306 holding by means of suction
• CPC Class Codes: A61B 2017/32004 having a laterally movable cutting member at its most distal end which remains within the contours of said end
• CPC Class Codes: A61B 90/92 coded with colour

Abstract

A multiple biopsy device has a number of chambers into which tissue samples are received. A cutting mechanism, such as a blade, moves relative to the chambers to cut a tissue sample that is within a chamber. In one embodiment of the invention, the multiple biopsy device is removably secured to the distal end of an endoscope/bronchoscope.

Claims

1. A device for obtaining multiple biopsy samples from a patient, comprising:

a cap including a step to engage the distal end face of an endoscope, the cap having first and second isolated biopsy chambers formed therein, each isolated biopsy chamber having an opening through which tissue can enter the biopsy chamber;

a tissue cutter associated with the cap such that relative movement between the cutter and the first biopsy chamber and subsequent relative movement between the cutter and the second biopsy chamber sequentially cuts tissue that has entered the first and second biopsy chambers.

2. The device of claim 1, wherein each biopsy chamber includes a port in fluid communication with a vacuum lumen of the endoscope such that when vacuum is applied to the vacuum lumen, tissue is drawn into the first and/or second biopsy chamber.

3. The device of claim 1, wherein each of the biopsy chambers is marked with a code or other identification.

4. The device of claim 1, wherein the biopsy chambers substantially face the same direction as the distal end face of the associated endoscope.

5. The device of claim 1, further comprising means for creating relative movement between the cutter and the first biopsy chamber and subsequent relative movement between the cutter and the second biopsy chamber.

6. The device of claim 5, wherein the means for creating relative movement comprises an actuating thread that moves the cutter relative to the openings of the biopsy chambers.

7. The device of claim 6, wherein the cutter is mounted on a rotating ring that is moved by the actuating thread over the openings of the biopsy chambers.

8. The device of claim 5, wherein the means for creating relative movement moves the chambers with respect to the cutter.

9. The device of claim 5, further comprising a seal for closing the first biopsy chamber once a tissue sample is cut and received therein.

10. The device of claim 9, wherein the seal closes the first biopsy chamber and subsequently opens the second biopsy chamber for subsequent tissue collection.

11. The device of claim 9, wherein the seal and the cutter are integrally formed.

12. The device of claim 1, further comprising an actuator that causes, under control of the user, relative movement between the cutter and the first and second biopsy chambers.

13. The device of claim 1, wherein the first and second biopsy chambers are configured to contain the tissue cut by the tissue cutter until subsequent removal of the device from the patient.

14. The device of claim 13, wherein the first and second biopsy chambers each include a port in fluid communication with a vacuum lumen of the endoscope such that when vacuum is applied to the vacuum lumen, tissue is drawn into the first and/or second biopsy chamber.

15. The device of claim 1, wherein the cap includes a central lumen with at least two different radii.

16. The device of claim 15, wherein the central lumen of the cap has a proximal portion with a first radius configured to mate with the outer diameter of the endoscope.

17. The device of claim 16, wherein the central lumen of the cap has a distal portion with a second radius, the second radius being smaller than the first radius.

18. The device of claim 15, wherein the at least two radii for the step that is configured to engage the distal end face of the endoscope.

19. The device of claim 1, wherein the cap abuts the distal end face of the endoscope.

20. A medical system for obtaining multiple biopsy samples from a patient, comprising:

an endoscope having a proximal end and a distal end;

a biopsy device configured to be removably secured to the distal end face of the endoscope, the biopsy device comprising;

a throughbore configured for interfacing with the distal end of the endoscope;

a plurality of biopsy chambers arranged around and outwardly of the throughbore, each of the biopsy chambers having an opening in which tissue can be received, wherein the openings of the biopsy chambers face outwardly of the distal end face of the endoscope;

a cutter for cutting tissue that enters the biopsy chambers;

an actuator that moves the cutter under control of the user in a sequential manner between the plurality of biopsy chambers; and

a seal for closing a biopsy chamber once tissue has been cut and received in the biopsy chamber.

21. The system of claim 20, wherein the biopsy device further comprises a rotatable ring having an opening that when positioned in front of the openings of the biopsy chambers allows tissue to enter the biopsy chambers, the cutter being fixedly attached to the ring adjacent the ring opening.

22. The system of claim 21, wherein the actuator imparts rotation on the ring.

23. The system of claim 20, wherein the plurality of chambers substantially face the same direction as the distal end face of the endoscope.

24. A method of obtaining multiple biopsy samples from a patient, comprising:

inserting an endoscope into a patient having a cap secured to a distal end face of the endoscope, the cap including two or more biopsy chambers which face outwardly of the distal end face of the endoscope;

obtaining a first tissue sample in a first biopsy chamber by applying vacuum to a first biopsy chamber to draw tissue into the first biopsy chamber;

moving the first biopsy chamber relative to a tissue cutter to cut the tissue from the patient;

sealing the first biopsy chamber;

thereafter obtaining a second tissue sample in a second biopsy chamber;

thereafter removing the endoscope from the patient; and

removing the tissue samples from the first and/or second biopsy chamber.

25. The method of claim 24, wherein the act of moving the first biopsy chamber relative to a tissue cutter comprises one of a group consisting of:

(a) rotating the tissue cutter relative to the first biopsy chamber; and

(b) rotating the first biopsy chamber relative to the tissue cutter.

26. The method of claim 24, wherein obtaining a tissue sample in a second chamber includes

moving the endoscope to a location within the patient different than the position where the first tissue sample was obtained;

applying vacuum to the second chamber to draw tissue into the second biopsy chamber;

moving, under control of the user, the second chamber relative to the tissue cutter to cut tissue from the patient; and

sealing the second chamber.