Tissue sampling device and method

• US 7,794,410 B2
• Filed: 12/15/2004
• Issued: 09/14/2010
• Est. Priority Date: 12/16/2003
• Status: Active Grant

• Current Assignee: IDEXX Laboratories Incorporated
• Original Assignee: IDEXX Laboratories Incorporated
• Inventors: Libby, Tracy Lynn Hessel, Djuranovic, Nevena Novkovic, Mikulka, Thomas Luke, Barski, Stanislaw Jr.
• Primary Examiner(s): Hindenburg; Max
• Assistant Examiner(s): Lloyd; Emily M
• Application Number:
  US11/012,395
• Publication Number:
  US 20050131313A1
• Time in Patent Office: 2,099 Days
• Field of Search: 600/564, 600/565, 600/566, 600/567, 600/562, 606/167, 606/184
• US Class Current: 600/567
• CPC Class Codes: A61B 10/0266 means for severing sample
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 17/32053 Punch like cutting instruments, e.g. using a cylindrical or oval knife A61B17/326 takes precedence; trepans A61B17/1695; for use on the cornea A61F9/007
• CPC Class Codes: A61B 2090/061 for measuring dimensions, e.g. length
• CPC Class Codes: A61B 2090/063 for measuring volume
• CPC Class Codes: A61B 2090/3937 Visible markers

Abstract

A device for obtaining a sample from inside a body includes a tubular body portion defining a chamber for receiving a sample of material therein; a plunger assembly operatively associated with the tubular body portion, the plunger assembly having a stopper slidably disposed within the chamber of the body portion; feedback elements provided on the tubular body and/or the plunger assembly for providing a user with audible and/or tactile indications regarding an amount of displacement of the plunger assembly relative to the body portion; and a cutting element is provided to facilitate sample removal.

Claims

1. A method of collecting a sample of material from a body, comprising the steps of:

providing a device for obtaining the sample of material, the device comprising;

a tubular body portion having an open distal end and defining a chamber for receiving the sample of material therein;

a plunger assembly operatively associated with the tubular body portion and having a stopper slidably disposed within the chamber of the body portion, the stopper being adapted for fluid tight engagement with the body portion;

feedback elements provided on at least one of the tubular body portion and the plunger assembly for providing a user of the sampling device with at least one of audible and tactile indications regarding an amount of displacement of the plunger assembly relative to the body portion; and

a plurality of cutting elements extending radially inwardly from the open distal end of the tubular body portion and angled into the tubular body portion, each of the cutting elements having an unsupported free end disposed within the tubular body portion, wherein the cutting element includes;

a pair of opposed arms extending toward the longitudinal central axis of the body portion; and

a third arm extending beyond the longitudinal central axis of the body portion, the third arm being disposed at a substantially equi-distant location between the pair of opposed arms;

placing the open distal end of the device against the material from which the sample is to be taken;

driving the body portion into the material an amount sufficient for a sample of the material to enter the chamber of the body portion;

rotating the body portion about a longitudinal axis thereof an amount sufficient for the cutting element to sever the sample of material from the remainder of the material; and

withdrawing the device from the remainder of the material.

2. The method according to claim 1, wherein the stopper of the plunger assembly is positioned proximate the distal end of the body portion when the device is driven into the material.

3. The method according to claim 2, wherein as the body portion is driven into the material the stopper is displaced in an axially proximal direction relative to the body portion.

4. The method according to claim 1, wherein the feedback elements include:

a series of annular grooves formed along the length of the chamber; and

a projection extending radially outward from the stopper of the plunger assembly.

5. The method according to claim 4, wherein as the stopper is displaced in an axially proximal direction relative to the body portion, the projection of the stopper inter-engages with the annular grooves formed in the chamber.

6. The method according to claim 4, wherein the annular grooves are provided at intervals which correspond to 150 μ

L of volume of the chamber of the body portion.

7. The method according to claim 4, wherein the body portion includes a metrical marking for each annular groove.

8. The method according to claim 1, wherein, as the body portion is driven into the material, the feedback elements provide the user with at least one of audible and tactile indications as to the volume of material collected into the chamber of the body portion.

9. The method according to claim 1, further comprising the step of driving the plunger assembly in a distal direction relative to the body portion to expel the sample therefrom.

10. The method according to claim 9, wherein the feedback elements provide the user with at least one of audible and tactile indications as to the quantity of sample expelled from the chamber of the body portion.

11. A device for obtaining a sample from inside a body, comprising:

a tubular body portion defining a chamber for receiving a sample of material therein, the body portion having an open distal end, a proximal end and defining a longitudinal central axis;

a plunger assembly operatively associated with the tubular body portion, the plunger assembly having a stopper slidably disposed within the chamber of the body portion, the stopper being adapted for fluid tight engagement with the body portion;

feedback elements provided on at least one of the tubular body portion and the plunger assembly for providing a user of the sampling device with at least one of audible and tactile indications regarding an amount of displacement of the plunger assembly relative to the body portion; and

a cutting element having a plurality of arms extending radially inwardly from the open distal end of the tubular body portion and angled into the tubular body portion, each of the arms having an unsupported free end disposed within the tubular body portion,

wherein the cutting element includes;

a pair of opposed arms extending toward the longitudinal central axis of the body portion; and

a third arm extending beyond the longitudinal central axis of the body portion, the third arm being disposed at a substantially equi-distant location between the pair of opposed arms.

12. The device according to claim 11, wherein the feedback elements include one of a groove and a projection formed along an inner surface of the chamber of the tubular body portion.

13. The device according to claim 12, wherein the groove and projection are annular.

14. The device according to claim 13, wherein the annular groove corresponds with a metrical marking provided on the tubular body portion.

15. The device according to claim 11, wherein the tubular body portion includes a series of metrical markings formed along the length thereof, and wherein a feedback element is provided in association with each metrical marking.

16. The device according to claim 11, wherein the open distal end of the tubular body portion has a frusto-conical shape over at least one of its outer and inner peripheries.

17. The device according to claim 11, wherein the tubular body portion defines a distal cutting edge.

18. The device according to claim 11, wherein the plunger assembly includes a rod operatively connected to the stopper and extending from the proximal end of the body portion.

19. The device according to claim 18, wherein the feedback elements include at least one of a series of grooves and a series of projections formed along the length of the rod.

20. The device according to claim 18, wherein the feedback elements include one of a groove and a projection provided at the proximal end of the tubular body for inter-engaging the grooves or projections formed on the rod.

21. The device according to claim 11, wherein at least one of the plurality of arms extends into the chamber of the body portion proximal to the end of the body portion.