System and method for intraparenchymal drug infusion
First Claim
1. A method of performing an intraparenchymal drug infusion procedure, the method comprising:
- positioning an infusate exit port of a delivery tube at a target site;
infusing the target site with the drug by pumping the drug through an infusate pathway formed by the delivery tube;
monitoring pressure information indicative of an internal pressure of the infusate pathway while infusing the target site;
reviewing the monitored pressure for possible existence of a rising pressure period, a declining pressure period, and a substantially constant pressure period; and
evaluating infusate delivery effectiveness, including whether infusate was delivered to the target site and whether a therapeutically effective volume of distribution remains at the target site, based upon the monitored pressure and the review.
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Accused Products
Abstract
A system for performing an intraparenchymal drug infusion including a pump device, a delivery tube, a sensor, and a processor. The tube is fluidly coupled to the pump device, establishing an infusate pathway from the pump to an infusate exit port of the delivery tube. The sensor is positioned to sense a parameter indicative of pressure in the infusate pathway. Finally, the processor is programmed to generate information indicative of infusate delivery effectiveness of a drug infusion procedure based upon information from the sensor. In some embodiments, the processor generates a net infusion pressure profile, such as a pressure-time curve, and prompts display of the pressure profile to a neurosurgeon for subsequent evaluation of infusate delivery effectiveness.
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Citations
18 Claims
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1. A method of performing an intraparenchymal drug infusion procedure, the method comprising:
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positioning an infusate exit port of a delivery tube at a target site; infusing the target site with the drug by pumping the drug through an infusate pathway formed by the delivery tube; monitoring pressure information indicative of an internal pressure of the infusate pathway while infusing the target site; reviewing the monitored pressure for possible existence of a rising pressure period, a declining pressure period, and a substantially constant pressure period; and evaluating infusate delivery effectiveness, including whether infusate was delivered to the target site and whether a therapeutically effective volume of distribution remains at the target site, based upon the monitored pressure and the review. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification