Enhancement of lens regeneration using materials comprising polysiloxane polymers

• US 7,794,697 B2
• Filed: 04/26/2007
• Issued: 09/14/2010
• Est. Priority Date: 06/30/2004
• Status: Active Grant

• Current Assignee: Johnson & Johnson Surgical Vision, Inc. (Johnson & Johnson)
• Original Assignee: Abbott Medical Optics Incorporated (Johnson & Johnson)
• Inventors: Terwee, Thomas, Koopmans, Steven, Gwon, Arlene, Norrby, Sverker
• Primary Examiner(s): Hartley; Michael G
• Assistant Examiner(s): DICKINSON, PAUL W
• Application Number:
  US11/740,677
• Publication Number:
  US 20070219633A1
• Time in Patent Office: 1,237 Days
• Field of Search: None
• US Class Current: 424/78.08
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61L 2430/16 for reconstruction of eye parts, e.g. intraocular lens, cornea
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: C08L 83/04 Polysiloxanes

Abstract

The present invention addresses the treatment of ocular conditions by the enhancement of lens regeneration. Enhancement of lens regeneration is accomplished by the administration of a composition comprising a polysiloxane polymer having functional acryl groups useful in the preparation of intraocular lenses (IOLs).

Claims

1. A kit for enhancing regeneration of lens cells in a mammal after endocapsular extraction, comprising (i) an injectable polysiloxane polymer lens material having a backbone of general formula:

2. A kit according to claim 1 wherein said polysiloxane polymer is photocurable.

3. A kit according to claim 1 wherein said kit further comprises a collagen patch.

4. A kit according to claim 1 wherein said kit further comprises an intraocular lens.

5. A kit according to claim 1 wherein said kit further comprises a contact lens polymeric material in the form of a permeable or semi-permeable disc shaped lens.