×

Microarray and uses therefor

  • US 7,794,946 B1
  • Filed: 02/04/1999
  • Issued: 09/14/2010
  • Est. Priority Date: 02/04/1998
  • Status: Expired due to Fees
First Claim
Patent Images

1. A kit comprising:

  • at least one antibody array, said antibody array comprising a plurality of discrete locations arrayed in a spatially addressable ordered matrix on a solid surface, wherein each of the discrete locations comprises one or more spots of an antibody bound to the solid surface, wherein a plurality of the discrete locations contain antibodies that are different from the antibodies of the other discrete locations;

    a first detectable label for labeling a first protein sample;

    optionally a second detectable label for detectably labeling a second protein sample, wherein the second detectable label is different from the first detectable label; and

    instructions for using the kit to perform one or more of the following;

    i. identifying antigens in the first or the second protein samples that bind to one or more of the antibodies bound to the solid surface;

    ii. comparing the protein expression profiles of two or more protein samples;

    iii. characterizing the first or the second protein samples based on the protein expression profile thereof; and

    iv. determining the effect of varying binding conditions on the affinity of the bound antibodies to antigens present in first or second protein samples.

View all claims
  • 4 Assignments
Timeline View
Assignment View
    ×
    ×