Auditory midbrain implant

• US 7,797,029 B2
• Filed: 10/25/2002
• Issued: 09/14/2010
• Est. Priority Date: 10/26/2001
• Status: Expired due to Fees

• Current Assignee: Cochlear Limited
• Original Assignee: Cochlear Limited
• Inventors: Mackiewicz, Miro, Lenarz, Minoo, Gibson, Peter, Parker, John, Patrick, James Finlay, Lenarz, Thomas
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Patel; Natasha N
• Application Number:
  US10/493,675
• Publication Number:
  US 20050004627A1
• Time in Patent Office: 2,881 Days
• Field of Search: 600372- 3, 600377- 9, 600/393, 607/115, 607/116, 607/137, 607/148
• US Class Current: 600/378
• CPC Class Codes: A61F 11/04 Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense, e.g. through the touch sense electronic stimulation of auditory nerves A61N1/36036
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0541 Cochlear electrodes

Abstract

An electrode array that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array an elongate member having a plurality of electrodes mounted thereon in a longitudinal array. A delivery cannula for delivering the electrode array comprised of two half-pipes is also described.

Claims

1. A brain stimulating electrode array for implantation into the inferior colliculus, the inferior colliculus having a central nucleus surrounded by an outer layer having a thickness and an exterior surface, the electrode array comprising:

a substantially straight elongate member configured to be inserted into an inferior colliculus of an implantee, and having;

a tip at a distal end of said elongate member configured to assist in passage of said member into the inferior colliculus and so as to cause minimal trauma to the inferior colliculus; and

a plurality of electrodes wherein each of said electrodes comprises an operative edge that is substantially perpendicular to said elongate member, and wherein the plurality of electrodes are spaced apart from one another along said elongate member and configured to apply pre-selected tissue stimulation to one or more layers of the different frequency layers of the inferior colliculus; and

a skirt radially extending from the elongate member, the skirt proximally spaced from a most proximal electrode of the plurality of electrodes by a distance approximately equal to the thickness of the outer layer.

2. The brain stimulating electrode array of claim 1, wherein said plurality of electrodes comprises between about 4 and 80 electrodes.

3. The brain stimulating electrode array of claim 2, wherein said plurality of electrodes comprises about 20 electrodes.

4. The brain stimulating electrode array of claim 1, wherein said plurality of electrodes are disposed in a longitudinal array on said elongate member.

5. The brain stimulating electrode array of claim 4, wherein said plurality of electrodes are equally spaced along said elongate member.

6. The brain stimulating electrode array of claim 1, wherein each of said plurality of electrodes comprises at least one single penetrating pin.

7. The brain stimulating electrode array of claim 1, wherein each of said plurality of electrodes is selected from a group comprising a ring, a half ring, a flat pad, and a multiple number of pins or pads around the circumference of said elongate member.

8. The brain stimulating electrode array of claim 7, wherein each of said plurality of electrodes are substantially identical in form.

9. The brain stimulating electrode array of claim 7, wherein at least one of said plurality of electrodes has a first form, and wherein at least one of said other electrodes has a second form.

10. The brain stimulating electrode array of claim 1, wherein each of said plurality of electrodes has a width of between about 50 microns and about 2000 microns.

11. The brain stimulating electrode array of claim 10, wherein each of said plurality of electrodes has a width of about 100 microns.

12. The brain stimulating electrode array of claim 1, wherein the spacing between each of said plurality of electrodes is between about 50 microns and about 2000 microns.

13. The brain stimulating electrode array of claim 12, wherein the spacing between each of said plurality of electrodes is about 100 microns.

14. The brain stimulating electrode array of claim 4, wherein said array has a length of between about 2 mm and about 6 mm.

15. The brain stimulating electrode array of claim 14, wherein said array has a length of about 4 mm.

16. The brain stimulating electrode array of claim 1, wherein the diameter of said elongate member begins to decrease proximate the distal end to said tip.

17. The brain stimulating electrode array of claim 16, wherein said tip is formed of a biocompatible material.

18. The brain stimulating electrode array of claim 1, wherein said elongate member has a body formed from a biocompatible material.

19. The brain stimulating electrode array of claim 18, wherein said elongate body has a diameter of about 0.2 mm to about 2 mm.

20. The brain stimulating electrode array of claim 19, wherein said elongate body has a diameter of about 0.5 mm.

21. The brain stimulating electrode array of claim 1, wherein said skirt is adapted to collapse on insertion of said elongate member through a delivery cannula but expand on exiting a distal end of the cannula.

22. The brain stimulating electrode array of claim 21, wherein said skirt is spaced a distance of between about 6 mm and about 6.5 mm from said distal tip and is adapted to stabilize said elongate member in a portion of the brain and ensure that said elongate member does not migrate further into said portion following correct placement.

23. The brain stimulating electrode array of claim 22, wherein said skirt has a plurality of fold lines and/or ribs formed therein so as to allow said skirt to collapse on insertion through the delivery cannula.

24. The brain stimulating electrode array of claim 23, wherein said skirt is adapted to collapse and/or expand in a spiral fashion.

25. The brain stimulating electrode array of claim 1, wherein said elongate member has a stiffening element extending at least partially therethrough.

26. The brain stimulating electrode array of claim 25, wherein said stiffening element is non-removably positioned in said elongate member.

27. The brain stimulating electrode array of claim 1, further comprising:

a lumen at least partially extending through said elongate member; and

a stiffening element removably positioned in at least a portion of said lumen to assist in implantation of said array.

28. The brain stimulating electrode array of claim 27, wherein said stiffening element comprises:

a removable wire stylet.

29. The brain stimulating electrode array of claim 27, wherein said stiffening element comprises:

a bioresorbable stylet configured to dissolve upon exposure to body fluid.

30. The brain stimulating electrode array of claim 27, wherein said stiffening element comprises:

a first portion positioned in said lumen having a first cross-section, and

a second portion connected to said first portion having a second cross-section that is larger than said first cross-section.

31. The brain stimulating electrode array of claim 1, wherein said elongate member comprises:

a lumen at least partially extending through said elongate member, wherein said lumen is configured for the delivery of bioactive agents to the inferior colliculus.

32. The brain stimulating electrode array of claim 1, wherein the skirt extends completely around a circumference of the electrode array.