Reduction of constituents in tobacco

• US 7,798,151 B2
• Filed: 07/18/2003
• Issued: 09/21/2010
• Est. Priority Date: 07/18/2002
• Status: Active Grant

• Current Assignee: Phasex Corporation, US Smokeless Tobacco Company LLC
• Original Assignee: Phasex Corporation, US Smokeless Tobacco Company LLC
• Inventors: Gudinas, Anthony, Schonemann, Hans, Wetmore, Paula M., Bennett, Clifford Brown, Krukonis, Val, Williams, Kara, Zheng, Harry Y., Johnston, Kathleen S., Midgett, Carl H.
• Primary Examiner(s): LOPEZ, CARLOS N
• Application Number:
  US10/623,006
• Publication Number:
  US 20040112394A1
• Time in Patent Office: 2,622 Days
• Field of Search: 131/291, 131/296, 131/298, 131/900
• US Class Current: 131/296
• CPC Class Codes: A24B 15/24 by extraction; Tobacco extracts
• CPC Class Codes: A24B 15/246 Polycyclic aromatic compounds
• CPC Class Codes: A24B 15/26 Use of organic solvents for extraction
• CPC Class Codes: A24B 15/287 by inorganic substances only
• CPC Class Codes: A24B 15/32 by acyclic compounds

Abstract

Methods of selectively reducing constituents in tobacco as well as the tobacco obtained by such methods are disclosed. Subcritical fluids, e.g., liquid carbon dioxide, serve as the reduction media.

Claims

1. A method of reducing an amount of a constituent in tobacco, said method comprising the steps of:

(a) providing a vessel containing said tobacco comprising said constituent;

(b) contacting said tobacco with a subcritical fluid consisting of carbon dioxide or a hydrocarbon under conditions so that said amount of said constituent dissolves in said subcritical fluid, wherein said subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is ethane at 0-30°

C. and 500-2000 psi;

said subcritical fluid is propane at 0-50°

C. and 100-2000 psi and the tobacco of step (a) has a moisture content of at least 30%;

or said subcritical fluid is Freon 22 at 0-50°

C. and 100-2000 psi;

or said subcritical fluid is butane and the tobacco of step (a) has a moisture content of at least 30%; and

(c) removing said subcritical fluid from said vessel;

thereby reducing the amount of said constituent in said tobacco.

8. The method of any of claims 1-5, wherein in step (b), said subcritical fluid is a liquid.

9. The method of claim 8, wherein said liquid is a compressed gas.

10. The method of any of claims 1-5, wherein in step (b), said subcritical fluid is a compressible gas.

11. The method of claim 1, further comprising, after step (c), the step of separating said constituent from said subcritical fluid.

14. The method of claim 11, wherein said separating comprises flowing said fluid containing said constituent from step (c) into a separator vessel containing a substance capable of separating said constituent from said subcritical fluid.

15. The method of claim 14, wherein said substance comprises citric acid or magnesium silicate.

19. The method of claim 11, wherein said separating comprises flowing said subcritical fluid containing said constituent from step (c) into a separator vessel, wherein said subcritical fluid undergoes a change in pressure or temperature and said constituent precipitates.

22. The method of claim 11, further comprising, after said separating, the step of recirculating said subcritical fluid to said vessel.

25. The method of claim 22, wherein during said recirculating, flavor or aroma compounds removed in step (b) are deposited in said tobacco after step (c).

28. The method of any of claims 1-5, wherein said subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi, and the tobacco of step (a) has a moisture content of at least 30%.

29. The method of any of claims 1-5, wherein the subcritical fluid is ethane at 0-30°

C. and 500-2000 psi or Freon 22 at 0-50°

C. and 100-2000 psi, and the tobacco of step (a) has a moisture content of at least 20%.

30. The method of claim 1, 3, 4 or 5, wherein the pH of said tobacco in step (a) is between 4 and 9.

31. The method of claim 1 or 5, wherein said constituent is a PAH.

32. The method of claim 1 or 5, wherein said constituent is a secondary alkaloid.

39. The method of claim 1, wherein the subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi, propane at 0-50°

C. and 100-2000 psi, or butane, and the tobacco of step (a) has a moisture content of at least 40%.

40. The method of claim 39, wherein the subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi, propane at 0-50°

C. and 100-2000 psi, or butane, and the tobacco of step (a) has a moisture content of at least 50%.

41. The method of claim 1, wherein the subcritical fluid is ethane at 0-30°

C. and 500-2000 psi or Freon 22 at 0-50°

C. and 100-2000 psi, and the tobacco of step (a) has a moisture content of at least 30%.

42. The method of claim 1, wherein the subcritical fluid is ethane at 0-30°

C. and 500-2000 psi or Freon 22 at 0-50°

C. and 100-2000 psi, and the tobacco of step (a) has a moisture content of at least 40%.

2. A method of selectively reducing an amount of a secondary alkaloid relative to a primary alkaloid in tobacco, said method comprising the steps of:

(a) providing a vessel containing said tobacco comprising said secondary alkaloid and said primary alkaloid;

(b) contacting said tobacco with a subcritical fluid under conditions so that a greater amount of said secondary alkaloid relative to said primary alkaloid dissolves in said subcritical fluid, wherein said subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is ethane at 0-30°

C. and 500-2000 psi;

said subcritical fluid is propane at 0-50°

C. and 100-2000 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is Freon 22 at 0-50°

C. and 100-2000 psi;

or said subcritical fluid is butane and the tobacco of step (a) has a moisture content of at least 30%; and

(c) removing said subcritical fluid from said vessel,

thereby selectively reducing the amount of said secondary alkaloid relative to said primary alkaloid in said tobacco.

12. The method of claim 2, further comprising, after step (c), the step of separating said secondary alkaloid from said subcritical fluid.

16. The method of claim 12, wherein said separating comprises flowing said fluid containing said secondary alkaloid from step (c) into a separator vessel containing a substance capable of separating said secondary alkaloid from said subcritical fluid.

17. The method of claim 16, wherein said substance comprises citric acid or magnesium silicate.

20. The method of claim 12, wherein said separating comprises flowing said subcritical fluid containing said secondary alkaloid from step (c) into a separator vessel, wherein said subcritical fluid undergoes a change in pressure or temperature and said secondary alkaloid precipitates.

23. The method of claim 12, further comprising, after said separating, the step of recirculating said subcritical fluid to said vessel.

26. The method of claim 23, wherein during said recirculating, flavor or aroma compounds removed in step (b) are deposited in said tobacco after step (c).

3. A method of reducing an amount of a polycyclic aromatic hydrocarbon (PAH) in tobacco, said method comprising the steps of:

(a) providing a vessel containing said tobacco comprising said PAH;

(b) contacting said tobacco with a subcritical fluid under conditions so that said amount of said PAH dissolves in said subcritical fluid, wherein said subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is ethane at 0-30°

C. and 500-2000 psi;

said subcritical fluid is propane at 0-50°

C. and 100-2000 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is Freon 22 at 0-50°

C. and 100-2000 psi;

or said subcritical fluid is butane and the tobacco of step (a) has a moisture content of at least 30%; and

(c) removing said subcritical fluid from said vessel;

thereby reducing the amount of said PAH in said tobacco.

13. The method of claim 3 or 4, further comprising, after step (c), the step of separating said PAH from said subcritical fluid.

18. The method of claim 13, wherein said separating comprises flowing said fluid containing said PAH from step (c) into a separator vessel containing a substance capable of separating said PAH from said subcritical fluid.

21. The method of claim 13, wherein said separating comprises flowing said subcritical fluid containing said PAH from step (c) into a separator vessel, wherein said subcritical fluid undergoes a change in pressure or temperature and said PAH precipitates.

24. The method of claim 13, further comprising, after said separating, the step of recirculating said subcritical fluid to said vessel.

27. The method of claim 24, wherein during said recirculating, flavor or aroma compounds removed in step (b) are deposited in said tobacco after step (c).

4. A method of selectively reducing an amount of a PAH relative to a primary alkaloid in tobacco, said method comprising the steps of:

(a) providing a vessel containing said tobacco comprising said PAH and said primary alkaloid;

(b) contacting said tobacco with a subcritical fluid under conditions so that a greater amount of said PAH relative to said primary alkaloid dissolves in said subcritical fluid, wherein said subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is ethane at 0-30°

C. and 500-2000 psi;

said subcritical fluid is propane at 0-50°

C. and 100-2000 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is Freon 22 at 0-50°

C. and 100-2000 psi;

or said subcritical fluid is butane and the tobacco of step (a) has a moisture content of at least 30%; and

(c) removing said subcritical fluid from the vessel,

thereby selectively reducing the amount of said PAH relative to said primary alkaloid in said tobacco.

5. A method of reducing an amount of a constituent in tobacco, said method comprising the steps of:

(a) providing a system comprising a plurality of connected vessels containing said tobacco comprising said constituent;

(b) contacting tobacco in a first vessel with a subcritical fluid under conditions so that said amount of said constituent dissolves in said subcritical fluid, wherein said subcritical fluid is carbon dioxide at 0-24°

C. and 1000-2200 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is ethane at 0-30°

C. and 500-2000 psi;

said subcritical fluid is propane at 0-50°

C. and 100-2000 psi and the tobacco of step (a) has a moisture content of at least 30%;

said subcritical fluid is Freon 22 at 0-50°

C. and 100-2000 psi;

or said subcritical fluid is butane and the tobacco of step (a) has a moisture content of at least 30%;

(c) removing said subcritical fluid from said first vessel; and

(d) directing said subcritical fluid to a second vessel;

thereby reducing the amount of said constituent in said tobacco in said first vessel.

6. The method of claim 5, further comprising the steps, before, during, or after step (c) of:

(i) isolating said first vessel from said system; and

(ii) removing said tobacco from said first vessel.

7. The method of claim 5, wherein in step (d), said subcritical fluid is that of step (c).

33. The method of claim 5, further comprising after step (c), the step of separating said constituent from said subcritical fluid.

34. The method of claim 33, wherein said second vessel in step (d) contains a substance capable of separating said constituent from said subcritical fluid.

35. The method of claim 34, wherein said substance comprises citric acid or magnesium silicate.

36. The method of claim 33, wherein said subcritical fluid in the second vessel undergoes a change in pressure or temperature and said constituent precipitates.

37. The method of claim 33, further comprising, after said separating, the step of recirculating said subcritical fluid to the first vessel.

38. The method of claim 37, wherein during said recirculating, flavor or aroma compounds removed in step (b) are redeposited in said tobacco after step (c).

43. A method of selectively reducing an amount of a secondary alkaloid relative to a primary alkaloid in tobacco, said method comprising the steps of:

(a) providing a vessel containing said tobacco comprising said secondary alkaloid and said primary alkaloid;

(b) contacting said tobacco with a subcritical fluid under conditions so that a greater amount of said secondary alkaloid relative to a said primary alkaloid dissolves in said subcritical fluid;

(c) removing said subcritical fluid from said vessel,

(d) separating said secondary alkaloid from the subcritical fluid in step (c), wherein said separating comprises flowing the subcritical fluid containing said secondary alkaloid from step (c) into a separator vessel containing a substance capable of separating said secondary alkaloid from the subcritical fluid, wherein the substance comprises citric acid or magnesium silicate;

thereby selectively reducing the amount of said secondary alkaloid relative to said primary alkaloid in said tobacco.