Dispenser and method for storing and dispensing sterile food product

• US 7,798,185 B2
• Filed: 11/05/2007
• Issued: 09/21/2010
• Est. Priority Date: 08/01/2005
• Status: Expired due to Fees

• Current Assignee: Medical Instill Technologies Inc.
• Original Assignee: Medical Instill Technologies Inc.
• Inventors: Chan, Julian V., Py, Daniel, Assion, Norbert M.
• Primary Examiner(s): Douglas; Steven O
• Application Number:
  US11/935,194
• Publication Number:
  US 20080135130A1
• Time in Patent Office: 1,051 Days
• Field of Search: 141/2, 141/18, 141/21, 141/27, 141/85, 141/329, 222/386, 222/390, 222/494, 222/563, 604/256, 604/415
• US Class Current: 141/329
• CPC Class Codes: A45D 2200/055 Piston or plunger for supplying the liquid to the applicator
• CPC Class Codes: A45D 34/04 Appliances specially adapted for applying liquid, e.g. using roller or ball
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 7/0053 Syringes, pipettes or oral dispensers
• CPC Class Codes: B05B 11/02 Membranes or pistons acting on the contents inside the container, e.g. follower pistons
• CPC Class Codes: B65D 51/002 Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
• CPC Class Codes: B67D 99/00 Subject matter not provided for in other groups of this subclass
• CPC Class Codes: G01F 11/027 of the syringe type

Abstract

A syringe is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials which may react upon exposure to air, such as glue. The syringes include a body and a plunger. Means are provided in the syringe body and the plunger to effect controlled movement of the plunger into the syringe to permit delivery of a pre-determined amount of the substance contained in the syringe. A one-way valve is provided at the dispensing tip of the syringe to hermetically seal the portion of the syringe containing the substance to be dispensed.

Claims

1. A method for aseptically storing and dispensing a sterile food product, comprising the following steps:

(i) maintaining a sterile food product hermetically sealed within a variable-volume storage chamber of a dispenser including a one-way valve coupled in fluid communication with the variable-volume storage chamber, wherein the one-way valve includes an elastic valve member forming a normally closed valve opening;

(ii) dispensing a plurality of different portions of the sterile food product at different points in time from the variable-volume storage chamber through the one-way valve by pressurizing sterile food at an inlet to the normally closed valve opening and in turn moving the elastic valve member between a normally closed position and an open position with at least a segment of the valve member spaced away from the closed position to allow the passage of sterile food product from the variable-volume storage chamber through the valve opening; and

(iii) maintaining the sterile food product within the variable-volume storage chamber sterile and hermetically sealed with respect to ambient atmosphere throughout steps (i) and (ii).

2. A method as defined in claim 1, further comprising the following steps:

(iv) sterile filling the variable-volume storage chamber with the sterile food product; and

(v) hermetically sealing the sterile food product within the variable-volume storage chamber.

3. A method as defined in claim 2, further comprising the step of substantially preventing the ingress of air or other contaminants through the one-way valve and into the variable-volume storage chamber during steps (iv) and (v).

4. A method as defined in claim 2, further comprising the step of sterilizing the food product prior to the step of sterile filling the variable-volume storage chamber with the food product.

5. A method as defined in claim 1, further comprising the step of manually manipulating a device that exerts pressure on the food product contained within a chamber of the dispenser and, in turn, dispensing a portion of the food product from the variable-volume storage chamber through the one-way valve.

6. A method as defined in claim 1, wherein the dispenser includes a penetrable and thermally resealable portion in fluid communication with the variable-volume storage chamber, and the method further comprises the steps of:

sterilizing an exposed surface of the penetrable and thermally resealable portion;

penetrating the penetrable and thermally resealable portion with a filling member coupled in fluid communication with a source of the sterile food product;

introducing the sterile food product through the filling member and into the variable-volume storage chamber;

withdrawing the filling member from the penetrable and thermally resealable portion; and

applying sufficient thermal energy to the penetrated region of the penetrable and thermally resealable portion to fuse the penetrated region and form a substantially gas-tight seal between the penetrated region and the variable-volume storage chamber.

7. A dispenser for storing and dispensing a sterile food product, comprising:

a variable-volume storage chamber, and a one-way valve coupled in fluid communication with sterile food product from the variable-volume storage chamber and including an elastic valve member forming a normally closed, axially-extending valve opening, wherein the valve member is movable between a normally closed position, and an open position with at least a segment of the elastic valve member spaced away from the closed position to allow the passage of the sterile food product through the valve opening, the variable-volume storage chamber is sterile filled with the rood product, the sterile food product is hermetically sealed in the variable-volume storage chamber, and the dispenser maintains the sterile food product within the variable-volume storage chamber sterile and hermetically sealed with respect to ambient atmosphere throughout dispensing a plurality of different portions of the sterile food product from the storage chamber through the one-way valve.

8. A dispenser as defined in claim 7, further comprising a housing defining the variable-volume storage chamber.

9. A dispenser as defined in claim 7, further comprising a device that exerts pressure on the food product contained within a chamber of the dispenser in order to dispense a plurality of different portions of the food product from the variable-volume storage chamber through the one-way valve.

10. A dispenser as defined in claim 9, further comprising a mechanism coupled to the device to move the device, exert pressure on the food product, and dispense a portion of the food product through the one-way valve.

11. A dispenser for storing sterile food and dispensing multiple portions of the sterile food therefrom, comprising:

a hermetically sealed, variable-volume storage chamber containing therein multiple portions of the sterile food hermetically sealed with respect to ambient atmosphere;

a one-way valve comprising a valve member formed of an elastic material and forming a normally closed valve opening and an inlet to the valve opening in fluid communication with the variable-volume storage chamber, wherein the valve member is movable radially in response to sterile food at the inlet to the valve opening exceeding a valve opening pressure between (i) a normally closed position and (ii) an open position with at least a segment of the valve member spaced radially away from the closed position to allow sterile food to be dispensed through the valve opening; and

a device in fluid communication with the variable-volume storage chamber and one-way valve and configured to exert pressure on sterile food at the inlet of the valve opening to exceed the valve opening pressure and dispense a portion of the sterile food through the one-way valve, wherein during dispensing of sterile food through the one-way valve, the one-way valve and the variable volume storage chamber maintain the sterile food remaining in the variable volume storage chamber sterile and sealed with respect to ambient atmosphere.

12. A dispenser as defined in claim 11, further comprising a manually-engageable mechanism coupled to the device to move the device, exert pressure on the food, and dispense a portion of the food through the one-way valve.

13. A dispenser for storing and dispensing multiple portions of a sterile food, comprising:

a variable-volume storage chamber including a plurality of portions of sterile food hermetically sealed therein;

means coupled in fluid communication with the variable-volume storage chamber for forming a normally closed opening, for moving between a normally closed position, and an open position with at least a segment of said means spaced away from the closed position to allow the passage of sterile food through the opening, and for maintaining the sterile food within the variable-volume storage chamber sterile and hermetically sealed with respect to ambient atmosphere throughout dispensing a plurality of different portions of the sterile food from the storage chamber therethrough; and

a device in fluid communication with the variable-volume storage chamber and said means and configured to exert pressure on sterile food at the opening and dispense a portion of the sterile food through said means.

14. A dispenser as defined in claim 13, wherein said means is a one-way valve comprising a valve member formed of an elastic material and forming a normally closed valve opening and an inlet to the valve opening in fluid communication with the variable-volume storage chamber, wherein the valve member is movable radially in response to sterile food at the inlet to the valve opening exceeding a valve opening pressure between (i) a normally closed position and (ii) an open position with at least a segment of the valve member spaced radially away from the closed position to allow sterile food to be dispensed through the valve opening.