Reinforced small intestinal submucosa

• US 7,799,089 B2
• Filed: 10/10/2006
• Issued: 09/21/2010
• Est. Priority Date: 08/04/2000
• Status: Expired due to Fees

• Current Assignee: DePuy Synthes Products LLC (Johnson & Johnson)
• Original Assignee: DePuy Orthopaedics Incorporated (Johnson & Johnson)
• Inventors: Ferguson, Joe W., Plouhar, Pamela Lynn, Malaviya, Prasanna, Melican, Mora Carolynne
• Primary Examiner(s): Stewart; Alvin J
• Application Number:
  US11/548,071
• Publication Number:
  US 20070129811A1
• Time in Patent Office: 1,442 Days
• Field of Search: 623 2372- 2376, 623/23.61, 623/16.11, 606/151, 606/154
• US Class Current: 623/23.72
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/08 Muscles; Tendons; Ligaments sutures A61B17/04
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/3629 Intestinal tissue, e.g. small intestinal submucosa
• CPC Class Codes: A61L 27/3633 Extracellular matrix [ECM]
• CPC Class Codes: A61L 27/3641 characterised by the site of application in the body materials for artificial blood vessels A61L27/507; materials for use in artificial skin A61L27/60
• CPC Class Codes: A61L 27/3683 subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
• CPC Class Codes: A61L 27/40 Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence

Abstract

Bioprosthetic devices for soft tissue attachment, reinforcement, or construction are provided. The devices comprise a sheet of naturally occurring extracellular matrix and a sheet of synthetic mesh coupled to the naturally occurring extracellular matrix portion.

Claims

1. A bioprosthetic device comprising:

a sheet of naturally occurring extracellular matrix; and

a sheet of bioabsorbable synthetic mesh coupled to the sheet of naturally occurring extracellular matrix, wherein the sheet of synthetic mesh has a rate of absorption that is slower than a rate of absorption of the sheet of naturally occurring extracellular matrix.

2. The bioprosthetic device of claim 1, wherein the naturally occurring extracellular matrix is selected from the group consisting of intestine submucosa, stomach submusoca, bladder submucosa, alimentary submucosa, respiratory sumucosa and genital submucosa.