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Methods and devices for orthovoltage ocular radiotherapy and treatment planning

  • US 7,801,271 B2
  • Filed: 10/30/2008
  • Issued: 09/21/2010
  • Est. Priority Date: 12/23/2007
  • Status: Active Grant
First Claim
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1. A treatment planning method for treating a lesion on or adjacent to the retina of an eye of a patient (retinal lesion), by directing collimated X-radiation at the lesion in a patient'"'"'s eye, comprising(a) based on an aligned patient-eye position, establishing at least two treatment beam paths directed from a source of a collimated x-radiation beam through the patient'"'"'s sclera beyond the limbus and directed at the retinal lesion,(b) determining, based on the known spectral and intensity characteristics of the source beam along the established beam paths and from the coordinates of the lesion in the aligned patient-eye position, a total treatment time for irradiation along the beam paths that is effective to produce a desired radiation dose at the lesion of the patient'"'"'s eye, and(c) determining, based on the known spectral and intensity characteristics of the source beam along the established beam paths, and from the coordinates of the optic nerve in the aligned eye position, the extent and duration of eye movement away from the aligned patient-eye position in a direction that moves the patient'"'"'s optic nerve toward the irradiation beam that will be allowed during treatment, while still maintaining the radiation dose at the patient optic nerve below a predetermined dose level.

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