Needle insertion sensor

• US 7,803,128 B2
• Filed: 06/14/2007
• Issued: 09/28/2010
• Est. Priority Date: 04/30/2002
• Status: Expired due to Fees

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Simonsen, Jan H., Christensen, Lars Hofmann, Poulsen, Jens Ulrik
• Primary Examiner(s): Mendez; Manuel A
• Application Number:
  US11/763,024
• Publication Number:
  US 20070239133A1
• Time in Patent Office: 1,202 Days
• Field of Search: 604 65- 67, 604/890.1, 604/131, 128/DIG.12, 128/DIG.13
• US Class Current: 604/65
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor

Abstract

This invention relates to a doser comprising a syringe (2) with a needle (3) which extends beyond the doser (1), which comprises an engagement face (4) in the vicinity of the needle so that the engagement face rests against the surface of the tissue into which the needle is inserted. Detector means (5) are provided on said engagement face to sample signals on the skin of the patient. The invention further provides means (13) for receiving external information related to health monitoring of a patient. This provides a doser that may record heart rate, EKG, BGM and hypo-alarm administered medicine. The doser may further be arranged to calculate an appropriate dose of medication on the basis of a number of acquired inputs.

Claims

1. A method of determining the quantity of medication delivered from an injection device into biologic tissue comprising:

a) determining whether a needle is inserted into biologic tissue and if the needle is inserted into biologic tissue, measuring and recording the amount of medication injected, wherein when the needle is not inserted into biologic tissue, the amount of medication expelled through the needle is not recorded; and

b) repeating a) before medication is injected through the needle and summing the amount of medication injected through the needle into biologic tissue.

2. The method of claim 1, wherein the determining whether the needle is inserted into biologic tissue comprises recording changes in impedance to a circuit that is electrically connected to the needle.

3. The method of claim 2, wherein the impedance is measured by at least two sensors.

4. The method of claim 3, wherein the impedance is measured by at least one sensor connected to the needle, and at least one other sensor.

5. The method of claim 3, wherein at least one sensor which measures impedance comprises an electrode.

6. The method of claim 4, wherein the at least one sensor connected to the needle which measures impedance comprises an electrode.

7. The method of claim 4, wherein the at least one other sensor which measures impedance comprises an electrode.

8. The method of claim 1, wherein the medication is an insulin.

9. The doser according to claim 8, wherein the doser comprises an emitter for generating and emitting light and detector means for detecting light.

10. The doser according to claim 1, wherein the electrodes are sensitive to electrical signals.

11. The doser according to claim 1, wherein the electrodes are sensitive to optical signals.

12. A doser for determining the quantity of medication delivered from an injection device into biologic tissue, the doser comprising:

an injection device comprising a syringe with a needle, and an electrode, the injection device extending from the doser,

an engagement face in the vicinity of the needle for engaging a surface of a tissue into which the needle is to be inserted, the engagement face comprising at least one additional electrode, wherein the electrodes are capable of detecting a physiological parameter in the tissue by generating electrical signals;

electrical circuits adapted to generate and receive electrical signals and configured to measure the impedance between electrodes, and determine whether a needle is inserted into biologic tissue, such that if the needle is inserted into biologic tissue, measuring and recording the amount of medication injected, and when the needle is not inserted into biologic tissue, the amount of medication expelled through the needle is not recorded, and summing and recording the amount of medication injected through the needle into biologic tissue, wherein the electrical circuits are adapted to determine the quantity of medication delivered from the injection device into biologic tissue.

13. The doser according to claim 12, wherein the signals are modulated.

14. The doser according to claim 12, wherein the electrical circuits comprise a calculating circuit and a storage circuit adapted to process and store the value of said signals.

15. The doser according to claim 12, wherein said engagement faces are positioned at one end of the doser, characterized in that the additional electrode means are arranged at the opposite end of the doser.

16. The doser according to claim 12, wherein said electrodes comprise a pair of mutually closely spaced electrodes.

17. The doser according to claim 16, wherein the doser is adapted to estimate electrocardiogram signals.

18. The doser according to claim 12, wherein the circuits are adapted to recognize specific signal shapes.

19. The doser according to claim 12, wherein the circuits are adapted to determine pulse rates.

20. The doser according to claim 12, wherein the circuits is adapted to calculate the blood glucose level.

21. The doser according to claim 20, wherein the circuits are adapted to calculate doses in dependence on the calculated blood glucose level.

22. The doser according to claim 21, wherein the circuits are adapted to control the generation of control signals to a pump in the doser.

23. The doser according to claim 12, wherein the doser is structured to receive external signals, and that the circuit in the doser is adapted to combine the external signals with signals from the detector.

24. The doser according to claim 23, wherein the doser is structured for wireless communication.