Methods for identification of merle gene
First Claim
Patent Images
1. A method for identifying a merle and/or a cryptic merle allele in a canine animal, the method comprising:
- analyzing a biological sample obtained from the canine animal for mutations in the SILV gene, wherein the presence of at least one insertion mutation at the boundary of intron 10 and exon 11 of the SILV gene indicates the canine animal has a merle or a cryptic merle allele, wherein the insertion comprises a short interspersed nucleotide element (SINE).
1 Assignment
0 Petitions
Accused Products
Abstract
Animals with mutations in SILV present with the merle coat color pattern phenotype. Methods for the identification of animals that harbor a mutation in the SILV gene are described. Mutations in the SILV gene can be identified from any biological sample such as a cell or tissue that contains genomic DNA. A microsatellite marker identified using linkage disequilibrium mapping that segregates with merle is also described.
-
Citations
11 Claims
-
1. A method for identifying a merle and/or a cryptic merle allele in a canine animal, the method comprising:
analyzing a biological sample obtained from the canine animal for mutations in the SILV gene, wherein the presence of at least one insertion mutation at the boundary of intron 10 and exon 11 of the SILV gene indicates the canine animal has a merle or a cryptic merle allele, wherein the insertion comprises a short interspersed nucleotide element (SINE). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
Specification