Biosensor coding system

• US 7,809,512 B2
• Filed: 11/11/2007
• Issued: 10/05/2010
• Est. Priority Date: 11/11/2007
• Status: Active Grant

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Perry, Joseph E.
• Primary Examiner(s): Bui, Bryan
• Application Number:
  US11/938,288
• Publication Number:
  US 20090125268A1
• Time in Patent Office: 1,059 Days
• Field of Search: 702/23, 702/85, 702/100, 204/403.01
• US Class Current: 702/23
• CPC Class Codes: G01N 33/48771 Coding of information, e.g. calibration data, lot number

Abstract

A biosensor system determines an analyte concentration using one or more calibrated correlation equations for an optical and/or electrochemical analysis of a biological fluid. The biosensor system may be implemented using a measurement device and a sensor strip. The measurement device applies test signals to a sequential conductive pattern on a sensor strip. The measurement device selectively and sequentially connects test contacts with conductive and non-conductive areas on the sequential conductive pattern, which generates code signals in response to the test signals. The measurement device uses the code signals to calibrate one or more of the correlation equations. The measurement device uses the calibrated correlation equations to determine the analyte concentration.

Claims

1. A biosensor for determining an analyte concentration in a biological fluid, comprising:

a measurement device having a processor connected to a pattern read device;

a sensor strip having a sequential conductive pattern, the sequential conductive pattern including conductive and non-conductive areas;

where the measurement device and sensor strip implement an analyte analysis, where the analyte analysis has at least one correlation equation;

where the pattern read device applies test signals to the sequential conductive pattern and includes test contacts, the pattern read device selectively and sequentially connecting the test contacts with conductive and non-conductive areas on the sequential conductive pattern;

where the sequential conductive pattern generates at least two code signals in response to the test signals;

where the processor calibrates at least one correlation equation responsive to the code signals; and

where the processor determines an analyte concentration responsive to at least one calibrated correlation equation.

2. The biosensor of claim 1, where the pattern read device applies test signals to at least two test contacts, and where the pattern read device drives at least one test contact to ground.

3. The biosensor of claim 1, where the processor generates a check signal in response to the code signals.

4. The biosensor of claim 1, where the pattern read device drives at least one test contact partially to ground.

5. The biosensor of claim 1, where the processor determines coding information in response to the code signals.

6. The biosensor of claim 1, where the analyte analysis is an electrochemical analysis.

7. The biosensor of claim 1, where the processor checks for errors in the code signals.

8. The biosensor of claim 7, where the processor enforces at least one rule regarding simultaneously electrically connected signals.

9. A biosensor for determining an analyte concentration in a biological fluid, comprising:

a measurement device having a processor connected to a pattern read device, where the pattern read device has at least three test contacts;

a sensor strip having a sequential conductive pattern, where the sequential conductive pattern has at least one conductive area and at least one non-conductive area;

where the pattern read device applies test signals to at least two test contacts;

where the pattern read device drives at least one test contact to ground;

where the pattern read device selectively and sequentially connects the test contacts with the conductive and non-conductive areas on the sequential conductive pattern;

where the sequential conductive pattern generates at least two code signals in response to the test signals;

where the measurement device and sensor strip implement an analyte analysis, where the analyte analysis has at least one correlation equation;

where the processor calibrates at least one correlation equation responsive to the code signals; and

where the processor determines an analyte concentration responsive to at least one calibrated correlation equation.

10. The biosensor of claim 9, comprising at least one conductive area with a higher resistance than another conductive area.

11. The biosensor of claim 9, where the processor generates a check signal in response to the code signals.

12. The biosensor of claim 9, where the pattern read device drives at least one test contact partially to ground.

13. The biosensor of claim 9, where the processor determines coding information in response to the code signals.

14. The biosensor of claim 9, further comprising electrical detection circuitry.

15. The biosensor of claim 9, where the processor checks for errors in the code signals.

16. The biosensor of claim 15, where the processor enforces at least one rule regarding simultaneously electrically connected signals.

17. A method for calibrating an analysis of an analyte in a biological fluid, comprising:

applying test signals to a sequential conductive pattern, the sequential conductive pattern including conductive and non-conductive areas;

selectively and sequentially connecting test contacts with conductive and non-conductive areas on the sequential conductive pattern;

generating at least two code signals in response to the test signals;

calibrating at least one correlation equation in response to the code signals; and

determining an analyte concentration in response to at least one calibrated correlation equation;

where the analyte concentration is determined by

reacting the analyte through a chemical reaction selected from the group consisting of a reaction with a chemical indicator and a redox reaction, where the chemical reaction produces an output signal,

measuring the output signal, and

calculating the analyte concentration using the at least one calibrated correlation equation and the measured output signal.

18. The method of claim 17, further comprising applying test signals to at least two test contacts on the sequential conductive pattern, and driving at least one test contact to ground.

19. The method of claim 17, further comprising generating a check signal in response to the code signals.

20. The method of claim 17, further comprising driving at least one test contact partially to ground.

21. The method of claim 17, further comprising determining coding information in response to the code signals.

22. The method of claim 17, further comprising checking for errors in the code signals.

23. The method of claim 22, further comprising enforcing at least one rule regarding simultaneously electrically connected signals.