Method and apparatus for providing positive airway pressure to a patient

• US 7,810,496 B2
• Filed: 10/29/2007
• Issued: 10/12/2010
• Est. Priority Date: 06/03/1994
• Status: Expired due to Term

• Current Assignee: RIC INVESTMENTS LLC (Respironics Incorporated)
• Original Assignee: RIC INVESTMENTS LLC (Respironics Incorporated)
• Inventors: Estes, Mark C., Kepler, Jeff, Fiore, John, Mechlenburg, Douglas M., Ressler, Heather
• Primary Examiner(s): Yu; Justine R
• Assistant Examiner(s): MATTER, KRISTEN CLARETTE
• Application Number:
  US11/926,867
• Publication Number:
  US 20080053442A1
• Time in Patent Office: 1,079 Days
• Field of Search: 128/204.18, 12820421-20423, 128/204.26
• US Class Current: 128/204.21
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/204 used for inhalation control
• CPC Class Codes: A61M 16/205 used for exhalation control
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit

Abstract

A system including methods and apparatus for treatment of a medical disorder such as obstructive sleep apnea or congestive heart failure. The system involves applying a gain to flow rate of pressurized gas delivered to a patient during inspiratory and/or expiratory phases of a respiratory cycle to deliver the pressurized gas in proportion to the respective gains during inspiration and/or expiration. A base pressure may be applied in addition to the gain-modified pressures and an elevated pressure profile may be employed to assist or control inspiration. The system may be fully automated responsive to feedback provided by a flow sensor that determines the estimated patient flow rate. A leak computer can be included to instantaneously calculate gas leakage from the system. The system may be utilized in connection with conventional continuous positive airway pressure treatments, such as CPAP or bi-level positive airway pressure equipment to effect various beneficial treatment applications.

Claims

1. A method of delivering pressurized gas to an airway of a patient, comprising the steps of:

providing a gas flow generator and a patient interface adapted to couple the gas flow generator to an airway of a patient;

delivering a flow of gas to such a patient using the gas flow generator and the patient interface;

determining that the patient is experiencing an apnea;

increasing a pressure of the flow of gas for a predetermined amount of time responsive to determining that the patient is experiencing the apnea, and at an end of the predetermined amount of time decreasing the pressure of the flow of gas;

monitoring a change in flow rate for the flow of gas based on the pressure increase;

determining whether the apnea is central or obstructive based on whether the airway of the patient is open or closed based on the monitored change in flow rate; and

increasing the pressure of the flow of gas delivered to the patient by a predetermined amount in response to determining that the airway of the patient is closed based on the monitored change in flow rate.

2. The method of claim 1, wherein the delivering a flow of gas to the patient includes generating a flow of gas using a blower, and wherein the increasing the pressure of the flow of gas includes changing an operating speed of the blower.

3. The method of claim 1, wherein the delivering a flow of gas to the patient includes generating a flow of gas using an blower, and wherein the increasing the pressure of the flow of gas comprises:

(a) controlling a pressure controller valve provided downstream of the blower, (b) changing an operating speed of such a blower, or (c) controlling the valve and changing an operating speed of the blower.

4. The method of claim 1, wherein the delivering the flow of gas to the patient comprises:

differentiating between an expiratory phase and an inspiratory phase of a respiratory cycle of the patient;

establishing a reduced pressure profile for a pressure of the flow of gas provided to the patient, wherein the reduced pressure profile has a contour that is predetermined prior to initiation of the expiratory phase, and wherein the contour defines a changing pressure over a period of time; and

controlling the gas flow delivered to the patient so that (1) the pressure of the flow of gas is provided at a first pressure level during at least a portion of the inspiratory phase, and (2) the pressure of the flow of gas is provided according to the reduced pressure profile during at least a portion of the expiratory phase of the respiratory cycle.

5. The method of claim 1, further comprising selecting a first gain, and wherein delivering the flow of gas to the patient comprises:

monitoring a characteristic associated with the flow of gas; and

controlling the flow of gas such that the flow of gas is delivered to the patient at (1) a therapy pressure during at least a portion of an inspiratory portion of a respiratory cycle, wherein the therapy pressure is a pressure sufficient to counter airway collapsing forces, and (2) based on the first gain and the monitored characteristic during at least a portion of an expiratory phase of a respiratory cycle.

6. An apparatus adapted to deliver a flow of gas to an airway of a patient, the apparatus comprising:

(a) a gas flow generator adapted to generate a flow of gas;

(b) a conduit adapted to carry the flow of gas generated by the gas flow generator to the airway of the patient;

(c) a sensor coupled to the gas flow generator or the conduit and adapted to monitor a characteristic associated with the flow of gas; and

(d) a processor adapted to;

(1) determine that the patient is experiencing an apnea based on an output of the sensor,

(2) control the gas flow generator so as to increase a pressure of the flow of gas for a predetermined amount of time responsive to determining that the patient is experiencing the apnea, and at an end of the predetermined amount of time decrease the pressure of the flow of gas,

(3) monitor a change in flow rate for the flow of gas based on the pressure increase,

(4) determine whether the apnea is central or obstructive based on whether the airway of the patient is open or closed based on the monitored change in flow rate, and

(5) increase the pressure of the flow of gas delivered to the patient by a predetermined amount in response to determining that the airway of the patient is closed based on the monitored change in flow rate.

7. The apparatus of claim 6, wherein the gas flow generator is a blower, and wherein the increasing the pressure of the flow of gas includes changing an operating speed of the blower.

8. The apparatus of claim 6, wherein the gas flow generator is a blower, and wherein the increasing the pressure of the flow of gas comprises:

(a) controlling a pressure controller valve provided downstream of the blower, (b) changing an operating speed of such a blower, or (c) controlling the valve and changing an operating speed of the blower.

9. The apparatus of claim 6, wherein the processor is adapted to:

differentiate between an expiratory phase and an inspiratory phase of a respiratory cycle of the patient;

establish a reduced pressure profile for a pressure of the flow of gas provided to the patient, wherein the reduced pressure profile has a contour that is predetermined prior to initiation of the expiratory phase, and wherein the contour defines a changing pressure over a period of time; and

control the gas flow delivered to the patient so that (1) the pressure of the flow of gas is provided at a first pressure level during at least a portion of the inspiratory phase, and (2) the pressure of the flow of gas is provided according to the reduced pressure profile during at least a portion of the expiratory phase of the respiratory cycle.

10. The apparatus of claim 6, further comprising an input device adapted to select a first gain, and wherein the processor is adapted to:

monitor a characteristic associated with the flow of gas based on an output of the sensor; and

control the gas flow generator so that the flow of gas is delivered to the patient at (1) a therapy pressure during at least a portion of an inspiratory portion of a respiratory cycle, wherein the therapy pressure is a pressure sufficient to counter airway collapsing forces, and (2) based on the first gain and the output of the sensor during at least a portion of an expiratory phase of a respiratory cycle.