Method for treating chronic obstructive pulmonary disease

• US 7,811,274 B2
• Filed: 04/27/2004
• Issued: 10/12/2010
• Est. Priority Date: 05/07/2003
• Status: Expired due to Fees

• Current Assignee: Portaero, Inc
• Original Assignee: Portaero, Inc
• Inventors: Tanaka, Don, Russell, Scott M.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Gray; Phillip
• Application Number:
  US10/832,905
• Publication Number:
  US 20040225254A1
• Time in Patent Office: 2,359 Days
• Field of Search: 604/523, 604/53, 604/158, 604/280, 604/656
• US Class Current: 604/502
• CPC Class Codes: A61M 16/10 Preparation of respiratory gases or vapours
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 2202/0007 introduced into the body
• CPC Class Codes: A61M 2202/02 Gases
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/03 Gases in liquid phase, e.g. cryogenic liquids
• CPC Class Codes: A61M 2210/101 Pleural cavity
• CPC Class Codes: A61M 25/0041 pre-formed, e.g. specially adapted to fit with the anatomy of body channels urethral catheters A61F2/04

Abstract

A ventilation bypass system which alleviates symptoms of chronic obstructive pulmonary disease by allowing air to exit the lung of a patient through the thoracic wall bypassing the natural airways. A pleurodesis is formed between the visceral and parietal membranes surrounding a lung and an opening is made through the thoracic wall into the lung via the pleurodesis. The ventilation bypass system includes a conduit placed through the opening in the thoracic wall into the lung, a flange for securing the conduit to the thoracic wall and preventing over-insertion of the conduit, and a flow control device for controlling flow of material out of the lung.

Claims

1. A method for treating chronic obstructive pulmonary disease in a lung of a person, the person having a thoracic wall, a parietal membrane, a visceral membrane and a passage which passes through the thoracic wall, the parietal membrane and the visceral membrane into the lung, the parietal membrane being sealed to the visceral membrane surrounding the passage, wherein the method comprises:

(a) obtaining a ventilation bypass device having a conduit, a flange and a flow-control device, the conduit having an aperture at a distal end to admit gasses from the lung, the flow-control device being connected to a proximal end of the conduit to vent gasses from the conduit, and the flange extending from the conduit spaced from the distal end of the conduit;

(b) positioning the distal end of the conduit through the passage into the lung of the person;

(c) securing the flange to the thoracic wall of the person; and

(d) permitting gasses within the lung of the person to escape through the thoracic wall of the person by entering the aperture, passing through the conduit, and venting through the flow-control device external to the thoracic wall of the person.

2. The method of claim 1, wherein:

step (a) comprises obtaining a ventilation bypass device having a conduit, a flange and a flow-control device, the conduit having an aperture at a distal end to admit gasses from the lung, the flow-control device being connected to a proximal end of the conduit to vent gasses from the conduit, the flange extending from the conduit spaced from the distal end of the conduit, and a coupling plate having an adhesive coating; and

step (c) comprises securing the flange to the thoracic wall of the person with the adhesive coating of the coupling plate.

3. The method of claim 1, wherein:

step (a) comprises obtaining a ventilation bypass device having a conduit, a flange and a flow-control device, the conduit having an aperture at a distal end to admit gasses from the lung, the flow-control device comprising a filter connected to a proximal end of the conduit to vent gasses from the conduit, and the flange extending from the conduit spaced from the distal end of the conduit; and

step (d) comprises permitting gasses within the lung of the person to escape through the thoracic wall of the person by entering the aperture, passing through the conduit, and venting through the filter external to the thoracic wall of the person.

4. The method of claim 1, wherein:

step (a) comprises obtaining a ventilation bypass device having a conduit, a flange and a flow-control device, the conduit having an aperture at a distal end to admit gasses from the lung, the flow-control device comprising a valve connected to a proximal end of the conduit to vent gasses from the conduit, and the flange extending from the conduit spaced from the distal end of the conduit; and

step (d) comprises permitting gasses within the lung of the person to escape through the thoracic wall of the person by entering the aperture in the distal end of the conduit, passing through the conduit, and venting through the valve external to the thoracic wall of the person.

5. The method of claim 1, wherein:

step (a) comprises obtaining a ventilation bypass device having a conduit, a flange, a trap and a flow-control device, the conduit having an aperture at a distal end to admit gasses from the lung, the flow-control device being connected to a proximal end of the conduit by the trap; and

wherein the method further comprises (e) storing a discharge from the lung in the trap.

6. The method of claim 1, wherein step (c) comprises:

(c1) securing a coupling plate to the thoracic wall of the person adjacent the passage; and

(c2) securing the flange to the coupling plate.

7. The method of claim 1, wherein step (c) comprises:

(c1) securing a coupling plate to the thoracic wall of the person adjacent the passage with a biocompatible adhesive; and

(c2) securing the flange to the coupling plate.

8. The method of claim 1, further comprising:

(e) surgically creating said passage which passes through the thoracic wall, the parietal membrane and the visceral membrane into the lung; and

(f) sealing the parietal membrane and visceral membrane to one another surrounding the passage.

9. A method for increasing expiratory flow of gasses from a lung of a person, the person having a chest wall, a parietal membrane, a visceral membrane, and a pleural cavity and a passage which passes through the chest wall, the parietal membrane and the visceral membrane into the lung, the passage being sealed from the pleural cavity, wherein the method comprises:

(a) obtaining a ventilation device having a conduit, a shoulder and a gas-control device, the conduit having a distal aperture to admit gasses from the lung, the gas-control device being attached to a proximal end of the conduit, and the shoulder extending from the conduit spaced from the distal aperture;

(b) positioning the distal aperture of the conduit through the passage into the lung of the person;

(c) attaching the shoulder to the chest wall of the person; and

(d) permitting gasses to escape from the lung through the chest wall of the person by entering the distal aperture, passing through the conduit, and venting through the gas-control device external to the person.

10. The method of claim 9, wherein:

step (a) comprises obtaining a ventilation device having a conduit, a shoulder and a gas-control device, the conduit having a distal aperture to admit gasses from the lung, the shoulder having an adhesive, the gas-control device being attached to a proximal end of the conduit, the shoulder extending from the conduit spaced from the distal aperture, and a coupling plate having an adhesive coating; and

step (c) comprises attaching the conduit to the person with the adhesive coating of the coupling plate.

11. The method of claim 9, wherein:

(a) obtaining a ventilation device having a conduit, a shoulder and a gas-control device, the conduit having a distal aperture to admit gasses from the lung, the gas-control device comprising a filter connected to a proximal end of the conduit, and the shoulder extending from the conduit spaced from the distal aperture;

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal aperture, passing through the conduit, and venting through the filter external to the person.

12. The method of claim 9, wherein:

step (a) comprises obtaining a ventilation device having a conduit, a shoulder and a gas-control device, the conduit having a distal aperture to admit gasses from the lung, the gas-control device comprising a valve connected to a proximal end of the conduit, and the shoulder extending from the conduit spaced from the distal aperture; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal aperture, passing through the conduit, and venting through the valve external to the person.

13. The method of claim 9, wherein:

step (a) comprises obtaining a ventilation device having a conduit, a shoulder and a gas-control device, the conduit having a distal aperture to admit gasses from the lung, the gas-control device being attached to a proximal end of the conduit, and the shoulder extending from the conduit spaced from the distal aperture; and

wherein the method further comprises (e) storing a discharge from the lung in a trap.

14. The method of claim 9, wherein step (c) comprises:

(c1) attaching a coupling plate to the chest wall of the person adjacent the passage; and

(c2) attaching the shoulder to the coupling plate.

15. The method of claim 9, wherein step (c) comprises:

(c1) attaching a coupling plate to the chest wall of the person adjacent the passage with a biocompatible adhesive; and

(c2) attaching the shoulder to the coupling plate.

16. The method of claim 9, further comprising:

(e) surgically creating said passage which passes through the chest wall, the parietal membrane and the visceral membrane into the lung; and

(f) sealing the passage from the pleural cavity by causing pleurodesis between the parietal membrane and visceral membrane surrounding the passage.

17. A method for reducing hyperinflation of a lung of a person, the person having a chest wall, a parietal membrane, a visceral membrane, and a pleural cavity and a passage which passes through the chest wall, the parietal membrane and the visceral membrane into the lung, the passage being sealed from the pleural cavity, wherein the method comprises:

(a) receiving a gas venting device having a conduit, and a gas-control device, the conduit having a distal opening to admit gasses from the lung, the conduit having a projection extending from the conduit and spaced from the distal opening, the conduit being received through an aperture in a coupling plate such that the coupling plate is positioned between the projection and the distal opening, the gas-control device being connected to a proximal end of the conduit;

(b) inserting the conduit into the passage to position the distal opening within the lung of the person;

(c) contacting the chest wall of the person with the coupling plate;

(d) securing the coupling plate to the chest wall of the person;

(e) permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the conduit, and escaping through the gas-control device.

18. The method of claim 17, wherein:

step (a) comprises receiving a gas venting device having a conduit, and a gas-control device, the conduit having a distal opening to admit gasses from the lung, the conduit having a projection extending from the conduit and spaced from the distal opening, the conduit being received through an aperture in a coupling plate such that the coupling plate is positioned between the projection and the distal opening, the gas-control device including a filter connected to a proximal end of the conduit; and

step (e) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the conduit, and escaping through the filter.

19. The method of claim 17, wherein:

step (a) comprises receiving a gas venting device having a conduit, and a gas-control device, the conduit having a distal opening to admit gasses from the lung, the conduit having a projection extending from the conduit and spaced from the distal opening, the conduit being received through an aperture in a coupling plate such that the coupling plate is positioned between the projection and the distal opening, the gas-control device including a valve connected to a proximal end of the conduit; and

step (e) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the conduit, and escaping through the valve.

20. The method of claim 17, wherein:

step (a) comprises receiving a gas venting device having a conduit, and a gas-control device, the conduit having a distal opening to admit gasses from the lung, the conduit having a projection extending from the conduit and spaced from the distal opening, the conduit being received through an aperture in a coupling plate such that the coupling plate is positioned between the projection and the distal opening, the gas-control device including a filter and a valve connected to a proximal end of the conduit; and

step (e) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the conduit, and escaping through the filter and the valve.

21. The method of claim 17, wherein:

step (a) comprises receiving a gas venting device having a conduit, and a gas-control device, the conduit having a distal opening to admit gasses from the lung, the conduit having a projection extending from the conduit and spaced from the distal opening, the conduit being received through an aperture in a coupling plate such that the coupling plate is positioned between the projection and the distal opening, the gas-control device being connected to a proximal end of the conduit, the coupling plate having an adhesive coating; and

step (d) comprises securing the coupling plate to the chest wall of the person with the adhesive coating.

22. The method of claim 17, wherein:

step (a) comprises receiving a gas venting device having a conduit, a projection extending from the conduit and spaced from the distal opening, the conduit being received through an aperture in a coupling plate such that the coupling plate is positioned between the projection and the distal opening, a containment vessel, and a gas-control device, the conduit having a distal opening to admit gasses from the lung, the gas-control device being connected by the containment vessel to a proximal end of the conduit; and

wherein the method further comprises (f) storing a discharge from the lung in the containment vessel.

23. The method of claim 17, further comprising:

(f) creating said passage which passes through the chest wall, the parietal membrane and the visceral membrane into the lung; and

(g) sealing the passage from the pleural cavity by causing pleurodesis between the parietal membrane and visceral membrane surrounding the passage.

24. A method for treating chronic obstructive pulmonary disease of a lung of a person, the person having a thoracic wall, a parietal membrane, a visceral membrane and a passage which passes through the thoracic wall, the parietal membrane and the visceral membrane into the lung, there being pleurodesis between the parietal membrane and visceral membrane surrounding the passage, wherein the method comprises:

(a) receiving a medical device having a tube, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device being connected to a proximal end of the tube, and the projection extending from the tube spaced from the distal opening;

(b) inserting the tube through the passage;

(c) positioning the distal opening within the lung of the person;

(d) securing the projection of the tube to the chest wall of the person; and

(e) venting gasses from the lung of the person external to the person through the chest wall via the distal opening, the tube, and the gas-control device.

25. The method of claim 24, wherein:

step (a) comprises receiving a medical device having a tube, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device being connected to a proximal end of the tube, and the projection extending from the tube spaced from the distal opening, and a coupling plate having an adhesive coating; and

step (d) comprises securing the conduit to the chest wall of the person by using the adhesive coating to create a temporary seal between the coupling plate and the chest wall.

26. The method of claim 24, wherein:

step (a) comprises receiving a medical device having a tube, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device connected to a proximal end of the tube, the gas-control device including a filter, and the projection extending from the tube spaced from the distal opening;

step (e) comprises venting gasses from the lung of the person external to the person through the chest wall via the distal opening, the tube, and the filter;

while

(f) filtering said gasses with the filter to capture particulate matter.

27. The method of claim 24, wherein:

step (a) comprises receiving a medical device having a tube, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device connected to a proximal end of the tube, the gas-control device including a valve, and the projection extending from the tube spaced from the distal opening;

step (e) comprises venting gasses from the lung of the person external to the person through the chest wall via the distal opening, the tube, and the valve;

while

(f) maintaining flow of said gases through the tube in one direction with the valve.

28. The method of claim 24, wherein:

step (a) comprises receiving a medical device having a tube, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device connected to a proximal end of the tube, the gas-control device including a filter and a valve, and the projection extending from the tube spaced from the distal opening;

step (e) comprises venting gasses from the lung of the person external to the person through the chest wall via the distal opening, the tube, the valve and the filter;

while

(f) filtering said gasses with the filter to capture particulate matter and maintaining flow of said gases through the tube in one direction with the valve.

29. The method of claim 24, wherein:

step (a) comprises receiving a medical device having a tube, a vessel, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device connected by the vessel to a proximal end of the tube, the gas-control device including a filter, and the projection extending from the tube spaced from the distal opening;

step (e) comprises venting gasses from the lung of the person external to the person through the chest wall via the distal opening, the tube, the vessel, and the filter;

while

(f) filtering the gasses with the filter to capture particulate matter and trapping discharge in the vessel.

30. The method of claim 24, wherein:

step (a) comprises receiving a medical device having a tube, a projection and a gas-control device, the tube having a distal opening to admit gasses from the lung, the gas-control device connected by the vessel to a proximal end of the tube, the gas-control device including a discharge trap, and the projection extending from the tube spaced from the distal opening;

step (e) comprises venting gasses from the lung of the person external to the person through the chest wall via the distal opening, the tube, and the discharge trap;

while

(f) trapping discharge in the discharge trap.

31. The method of claim 24, wherein step (d) comprises:

(d1) securing a coupling plate to the chest wall of the person adjacent the passage; and

(d2) securing the projection to the coupling plate.

32. The method of claim 24, wherein step (d) comprises:

(d1) adhering a coupling plate to the chest wall of the person adjacent the passage with a biocompatible adhesive; and

(d2) securing the projection to the coupling plate.

33. The method of claim 24, further comprising:

(f) creating said passage which passes through the thoracic wall, the parietal membrane and the visceral membrane into the lung; and

(g) causing pleurodesis between the parietal membrane and visceral membrane surrounding the passage.

34. A method for treating chronic obstructive pulmonary disease by reducing lung volume of a person, the person having a chest wall, a parietal membrane, and a visceral membrane and a passage which passes through the chest wall, the parietal membrane and the visceral membrane into the lung, there being pleurodesis of the visceral membrane and parietal membrane surrounding the passage, wherein the method comprises:

(a) receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, and the flange extending from the tube spaced from the distal opening;

(b) inserting the distal opening of the tube through the passage into the lung of the person;

(c) securing the flange to the chest wall of the person; and

(d) permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the gas vent external to the person.

35. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the flange extending from the tube spaced from the distal opening, and a coupling plate having an adhesive coating; and

step (c) comprises securing the medical device to the chest wall of the person by using the adhesive coating to create a temporary seal between the coupling plate and the chest wall.

36. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a filter, and the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the filter external to the person;

while

(e) filtering said gasses with the filter to capture particulate matter.

37. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a valve, and the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through a valve external to the person;

while

(f) maintaining flow of said gases through the tube in one direction with the valve.

38. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a filter and a valve, and the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the filter and the valve external to the person;

while

(e) filtering said gasses with the filter to capture particulate matter and maintaining flow of said gases through the tube in one direction with the valve.

39. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a filter and a container, and the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the container and filter external to the person;

while

(e) filtering said gasses with the filter to capture particulate matter and trapping discharge in the container.

40. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a discharge trap, and the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the discharge trap external to the person;

while

(e) trapping discharge in the discharge trap.

41. The method of claim 34, wherein step (c) comprises:

(c1) securing a coupling plate to the chest wall of the person adjacent the passage; and

(c2) securing the flange to the coupling plate.

42. The method of claim 34, wherein step (c) comprises:

(c1) securing a coupling plate to the chest wall of the person adjacent the passage with a biocompatible adhesive; and

(c2) securing the flange to the coupling plate.

43. The method of claim 34, further comprising:

(e) surgically creating said passage which passes through the chest wall, the parietal membrane and the visceral membrane into the lung; and

(f) creating pleurodesis between the parietal membrane and visceral membrane surrounding the passage.

44. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a discharge trap, and the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the discharge trap external to the person;

while

(e) trapping discharge in the discharge trap; and

(f) removing at lease part of the discharge trap after accumulation of discharge.

45. The method of claim 34, wherein:

step (a) comprises receiving a medical device having a tube, a flange and a gas vent, the tube having a distal opening to admit gasses from the lung, the gas vent being positioned at a proximal end of the tube, the gas vent including a discharge trap, the flange extending from the tube spaced from the distal opening; and

step (d) comprises permitting gasses to escape from the lung through the chest wall of the person by entering the distal opening, passing through the tube, and escaping through the discharge trap external to the person;

while

(e) trapping discharge in the discharge trap; and

(f) cleaning the discharge trap.