Cosmetic compositions

• US 7,812,057 B2
• Filed: 08/25/2004
• Issued: 10/12/2010
• Est. Priority Date: 08/25/2004
• Status: Active Grant

• Current Assignee: Molecular Research Center Incorporated
• Original Assignee: Molecular Research Center Incorporated
• Inventors: Chomczynski, Piotr
• Primary Examiner(s): Azpuru; Carlos A
• Assistant Examiner(s): Mercier; Melissa S
• Application Number:
  US10/925,851
• Publication Number:
  US 20060045892A1
• Time in Patent Office: 2,239 Days
• Field of Search: 424/401
• US Class Current: 514/729
• CPC Class Codes: A61K 2800/75 Anti-irritant
• CPC Class Codes: A61K 8/345 containing more than one hydroxy group
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 7/00 Preparations for affecting hair growth

Abstract

A composition and method for improving skin appearance by reducing skin redness and symptoms associated with skin inflammation, irritation and skin aging by topically treating skin is disclosed. In this composition and method, an active material having the formula given below is applied to the patient at the site of said condition:

wherein R¹ is selected from —OH and C₁-C₃ alkyl OH; and R², R³, R⁴, R⁵ and R⁶ are independently selected from —H, —OH, C₁-C₆ alkyl, and C₃-C₆ cycloalkyl. The active material should contain no more than five —OH groups. Preferred active materials include 1,2-cyclohexanediol, 1,3-cyclohexanediol, 1,4-cyclohexanediol, 1,2,3-cyclohexanetriol, 1,3,5-cyclohexanetriol, and mixtures of those materials. A method of maintaining healthy hair and reducing hair loss using these actives is also disclosed.

Claims

1. A method of maintaining healthy skin and skin appearance in humans by achieving effects selected from reducing skin spots and blemishes;

soothing irritated skin;

reducing redness, swelling and skin scars;

maintaining skin texture;

unplugging clogged and inflamed pores; and

combinations thereof, comprising topically applying to a person in need of such treatment a composition consisting essentially of a safe and effective amount of an active material in the form of a cis/trans isomer mixture, selected from 1,4-cyclohexanediol, 1,3 cyclohexanediol, 1,2-cyclohexanediol, 1,2,3-cyclohexanetriol, 1,3,5-cyclohexanetriol, and mixtures thereof.

2. The method according to claim 1 wherein the active material is applied to the skin in an amount of from about 0.001 to about 10 mg/cm².

3. The method according to claim 2 wherein the composition additionally includes a topical cosmetic carrier.

4. The method according to claim 3 wherein the cosmetic carrier comprises a material selected from propylene glycol, glycerin, water, dimethylisosorbide, and mixtures thereof.

5. The method according to claim 3 wherein the carrier is formulated in a composition selected from solutions, suspensions, gels, pastes, solids and soaps.

6. The method according to claim 1 wherein the active material is selected from 1,2-cyclohexanediol, 1,3-cyclohexanediol, 1,4-cyclohexanediol, and mixtures thereof.

7. A method of maintaining healthy skin and skin appearance in humans by achieving effects selected from reducing skin spots and blemishes;

soothing irritated skin;

reducing redness, swelling and skin scars;

maintaining skin texture;

unplugging clogged and inflamed pores; and

combinations thereof, comprising (a) topically applying to a person in need of such treatment a composition consisting essentially of a safe and effective amount of an active material in the form of a cis/trans isomer mixture, selected from 1,4-cyclohexanediol, 1,3-cyclohexanediol, 1,2-cyclohexanediol, 1,2,3-cyclohexanetriol, 1,3,5-cyclohexanetriol, and mixtures thereof, and (b) orally administering to said person a medically active oral supplement.

8. The method of claim 7 where the oral supplement is a tomato product selected from juice, homogenate, condensate, paste, extracts, extracted products, and mixtures thereof.