Profiling tumor specific markers for the diagnosis and treatment of neoplastic disease
First Claim
1. An array for identifying a neoplastic source sample, comprising a plurality of neoplastic molecular markers arranged in an assayable format, said molecular markers being differentially expressed in a sample obtained from a subject afflicted with small cell lung cancer as compared to a comparable sample obtained from a subject not afflicted with small cell lung cancer;
- wherein said neoplastic molecular markers comprise protein markers of NeuroD2, ATH5, Sox1, Sox2, and LMO4; and
wherein said protein markers are used to detect the presence of small cell lung cancer.
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Abstract
A method of diagnosing cancer comprising the identification of neoplastic molecular markers is disclosed. Tumor-related or neoplastic molecular markers are identified from samples taken from a subject and the molecular profile of those markers is determined. Based upon the neoplastic molecular marker profile of the subject, the tumor sub-type is ascertained and an appropriate treatment protocols initiated.
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Citations
3 Claims
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1. An array for identifying a neoplastic source sample, comprising a plurality of neoplastic molecular markers arranged in an assayable format, said molecular markers being differentially expressed in a sample obtained from a subject afflicted with small cell lung cancer as compared to a comparable sample obtained from a subject not afflicted with small cell lung cancer;
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wherein said neoplastic molecular markers comprise protein markers of NeuroD2, ATH5, Sox1, Sox2, and LMO4; and wherein said protein markers are used to detect the presence of small cell lung cancer. - View Dependent Claims (2, 3)
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Specification