Porous membranes for medical implants and methods of manufacture
First Claim
1. A method of making a single-layer porous membrane for use in medical implants comprising:
- extruding a continuous fiber-forming biocompatible polymeric material through a reciprocating extrusion head to form an elongated fiber;
depositing the fiber with a width of 5 to 500 micrometers onto a substrate in a predetermined pattern of non-crossing traces, the traces extending adjacently from a first end to a second end of the substrate, each trace contacting its adjacent traces in an alternating manner, the traces defining a plurality of pores of predetermined sizes, the fiber having a predetermined viscous characteristic that enables adjacent traces to bond to each other; and
thermally drying the biocompatible material on the substrate to provide a stable, single-layer porous membrane.
3 Assignments
0 Petitions
Accused Products
Abstract
The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.
308 Citations
9 Claims
-
1. A method of making a single-layer porous membrane for use in medical implants comprising:
-
extruding a continuous fiber-forming biocompatible polymeric material through a reciprocating extrusion head to form an elongated fiber; depositing the fiber with a width of 5 to 500 micrometers onto a substrate in a predetermined pattern of non-crossing traces, the traces extending adjacently from a first end to a second end of the substrate, each trace contacting its adjacent traces in an alternating manner, the traces defining a plurality of pores of predetermined sizes, the fiber having a predetermined viscous characteristic that enables adjacent traces to bond to each other; and thermally drying the biocompatible material on the substrate to provide a stable, single-layer porous membrane. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
Specification