Method and apparatus for endoscopic access to the vagus nerve

• US 7,819,883 B2
• Filed: 03/13/2007
• Issued: 10/26/2010
• Est. Priority Date: 03/13/2007
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Smith, David J., Westlund, Randy W., Bly, Mark J., Caparso, Anthony V.
• Primary Examiner(s): Layno; Carl H.
• Assistant Examiner(s): MORALES, JON ERIC C
• Application Number:
  US11/685,476
• Publication Number:
  US 20080228194A1
• Time in Patent Office: 1,323 Days
• Field of Search: 600/104, 600/183, 600/129, 600/101, 606/185, 606/190, 606/189, 607/115
• US Class Current: 606/129
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61N 1/0556 Cuff electrodes

Abstract

An apparatus for performing a minimally-invasive surgical procedure in the vagus nerve region includes a cannula, an endoscopic dissection tool and a cradle assembly slideably disposed in a cannula lumen. The cradle assembly includes a C-ring, an electrode cuff disposed over an exterior surface of the C-ring, and a deployment device. The electrode cuff is adapted to wrap around the target nerve region or nerve branch to be stimulated when deployed from the C-ring using the deployment device. A method of performing a minimally invasive surgical procedure is also described.

Claims

1. A surgical apparatus for gaining access to a nerve region or nerve branch in a minimally invasive manner, the apparatus comprising:

a cannula including an elongated body having a proximal end and a distal end and a cannula lumen extending a length of the body;

a dissection tool adapted to slide within the cannula lumen, the dissection tool including a viewing device, a tissue separating member and an electrode adapted to acutely stimulate the nerve region or nerve branch; and

a cradle assembly adapted to slide within the cannula lumen, the cradle assembly having a first leg and a second leg extending proximally from a C-ring generally adapted to cradle a portion of the nerve region or nerve branch, an electrode cuff adapted to be disposed over an exterior surface of the C-ring, and a deployment device adapted to deploy the electrode cuff from the C-ring.

2. The surgical apparatus of claim 1, wherein the dissection tool further includes an aperture, wherein the at least one electrode is adapted to be extended and retracted through the aperture.

3. The surgical apparatus of claim 1, wherein the cradle has an exterior surface and an interior surface, the cradle comprising at least one electrode located on the interior surface, wherein the electrode is adapted to acutely stimulate the nerve region or nerve branch.

4. The surgical apparatus of claim 1, wherein the electrode cuff comprises a preformed cuff including at least one electrode disposed on an interior surface of the cuff, the electrode cuff adapted to wrap around the nerve or nerve branch when deployed.

5. The surgical apparatus of claim 4, wherein the preformed cuff includes at least one anode and at least one cathode disposed on the interior surface of the cuff, the at least one anode and at least one cathode adapted to chronically stimulate the nerve.

6. The surgical apparatus of claim 4, wherein the electrode cuff comprises a microstimulator.

7. The surgical apparatus of claim 6, wherein the microstimulator is tethered to the electrode cuff assembly.

8. The surgical apparatus of claim 1, wherein the electrode cuff comprises a preformed cuff adapted to wrap around the nerve region or branch and a microstimulator coupled to the electrode cuff.

9. The surgical apparatus of claim 1, further comprising one or more surgical tools adapted to be extended and retracted through a cannula lumen.

10. The surgical apparatus according to claim 1, wherein the nerve region or nerve branch is located along a vagus nerve.

11. A surgical apparatus for use with a cannula including an endoscopic dissection tool to deploy an electrode cuff about a target nerve site, the surgical apparatus comprising:

a cradle assembly including a first leg and a second leg extending proximally from a C-ring generally adapted to cradle a portion of a nerve, wherein the C-ring has an exterior surface and an interior surface, the cradle comprising at least one electrode located on the interior surface, wherein the electrode is adapted to acutely stimulate the nerve region or nerve branch;

an electrode cuff coupled to an exterior of the cradle; and

a deployment device adapted to deploy the electrode cuff from the cradle to the target nerve site.

12. The surgical apparatus according to claim 11, wherein the dissection tool comprises at least one electrode adapted to acutely stimulate the portion of the nerve.

13. The surgical apparatus of claim 11, wherein the electrode cuff comprises a preformed cuff adapted to wrap around the portion of the nerve when deployed and at least one electrode adapted to chronically stimulate the portion of the nerve disposed on an interior surface of the cuff.

14. The surgical apparatus of claim 13, wherein the electrode cuff comprises a microstimulator.

15. A method for gaining access to and stimulating a targeted nerve region or nerve branch, the method comprising:

accessing the targeted nerve region or nerve branch using a surgical apparatus comprising a cannula, a dissection tool including a viewing device and an electrode for acutely stimulating the nerve, and a cradle assembly including a C-ring and an electrode cuff including at least one electrode adapted to chronically stimulate a nerve, the electrode cuff disposed over an exterior surface of the C-ring and adapted to be deployed from the exterior surface of the C-ring to a nerve region or nerve branch to be chronically stimulated;

identifying and isolating potential target nerve regions or nerve branches;

acutely stimulating potential target nerve regions or nerve branches using the dissection tool electrode or the electrode on the interior surface of the C-ring;

selecting the target nerve region or branch to receive chronic stimulation;

deploying the electrode cuff to the target nerve region or nerve branch; and

chronically stimulating the target nerve region or nerve branch.

16. The method according to claim 15, where the targeted nerve region is the vagus nerve.

17. The method according to claim 15, wherein the step of selecting the target nerve branch or region to receive chronic stimulation includes using information gained by acutely stimulating potential nerve regions or nerve branches.

18. The method according to claim 15, further comprising using one or more additional surgical tools to further manipulate the potential target nerve region or nerve branch.