Oleaginous pharmaceutical and cosmetic foam
First Claim
1. An oleaginous foamable therapeutic composition, comprising:
- a. about 70% to about 96.5% of a solvent phase, wherein the solvent phase comprises;
i) a hydrophobic solvent, a silicone oil, or a mixture thereof andii) optionally an emollient, a co-solvent, or a mixture thereofb. at least a non-ionic surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition;
c. at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition;
d. a therapeutically effective amount of at least one active agent; and
f. at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition,wherein the composition forms a breakable foam upon dispensing that collapses upon application of shear force; and
wherein the specific gravity of the foam is less than about 0.5 g/mL; and
wherein the water content of the composition is less than about 30% by weight.
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Accused Products
Abstract
The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes at least one solvent selected from a hydrophobic solvent, a silicone oil, an emollient, a co-solvent, and mixtures thereof, wherein the solvent is present at a concentration of about 70% to about 96.5% by weight of the total composition, at least a non-ionic surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition; at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition; a therapeutically effective amount of at least one active agent; and at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition.
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Citations
67 Claims
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1. An oleaginous foamable therapeutic composition, comprising:
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a. about 70% to about 96.5% of a solvent phase, wherein the solvent phase comprises; i) a hydrophobic solvent, a silicone oil, or a mixture thereof and ii) optionally an emollient, a co-solvent, or a mixture thereof b. at least a non-ionic surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition; c. at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition; d. a therapeutically effective amount of at least one active agent; and f. at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition, wherein the composition forms a breakable foam upon dispensing that collapses upon application of shear force; and wherein the specific gravity of the foam is less than about 0.5 g/mL; and wherein the water content of the composition is less than about 30% by weight. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67)
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Specification