Optical-based sensing devices
First Claim
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1. An electro-optical sensing device for detecting the presence or concentration of an analyte, comprising:
- a housing having an outer surface;
a plurality of indicator molecules located on at least a portion of the outer surface of the housing;
a circuit board housed within the housing;
a first photodetector connected to the circuit board for detecting a response of the indicator molecules;
a second photodetector connected to the circuit board for detecting the response of a reference fluorescent element;
a radiation source positioned a distance above the photosensitive sides of the first and second photodetectors; and
a reflector spaced apart from said radiation source and attached to said circuit board.
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Abstract
The present invention provides an electro-optical sensing device for detecting the presence or concentration of an analyte. More particularly, the invention relates to (but is not in all cases necessarily limited to) optical-based sensing devices which are characterized by being totally self-contained, with a smooth and rounded oblong, oval, or elliptical shape (e.g., a bean- or pharmaceutical capsule-shape) and a size which permits the device to be implanted in humans for in-situ detection of various analytes.
165 Citations
18 Claims
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1. An electro-optical sensing device for detecting the presence or concentration of an analyte, comprising:
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a housing having an outer surface; a plurality of indicator molecules located on at least a portion of the outer surface of the housing; a circuit board housed within the housing; a first photodetector connected to the circuit board for detecting a response of the indicator molecules; a second photodetector connected to the circuit board for detecting the response of a reference fluorescent element; a radiation source positioned a distance above the photosensitive sides of the first and second photodetectors; and a reflector spaced apart from said radiation source and attached to said circuit board. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. An electro-optical sensing device for detecting the presence or concentration of an analyte, comprising:
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a housing having an outer surface; a plurality of indicator molecules located on at least a portion of the outer surface of the housing; a circuit board housed within the housing; a first photodetector connected to the circuit board for detecting a response of the indicator molecules; a second photodetector connected to the circuit board for detecting the response of a reference fluorescent element; a radiation source positioned a distance above the photosensitive sides of the first and second photodetectors; and a reflector spaced apart from the radiation source and having a reflective side that faces the radiation source; wherein said circuit board has a groove in the top side thereof and said reflector has an end inserted into said groove.
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Specification