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Method of making self-supporting therapeutic active-containing film

DC CAFC
  • US 7,824,588 B2
  • Filed: 04/14/2008
  • Issued: 11/02/2010
  • Est. Priority Date: 10/12/2001
  • Status: Expired due to Fees
First Claim
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1. A method of making a self-supporting therapeutic active-containing film comprising:

  • (a) Mixing at least one edible polymer component, a therapeutic active composition, and at least one polar solvent to form a matrix;

    (b) Forming a wet film from said matrix;

    (c) Removing said polar solvent from said matrix with heat and/or radiation energy by exposing said matrix to a temperature greater than the degradation temperature of said therapeutic active composition;

    wherein the temperature of the matrix is 100°

    C. or less during said step of removing said polar solvent from said matrix.

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