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Higher fullerenes useful as radical scavengers

  • US 7,825,161 B2
  • Filed: 12/15/2004
  • Issued: 11/02/2010
  • Est. Priority Date: 12/15/2003
  • Status: Active Grant
First Claim
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1. A method of scavenging free radicals, the method comprising:

  • administering one or more free radical scavenging compounds to a dermal substrate, andreducing the levels of free radicals without significantly increasing pro-oxidant activity while the one or more free radical scavenging compounds is on the dermal substrate and is exposed to irradiation,wherein the one or more free radical scavenging compounds are selected from the group consisting of C84 fullerene and C84(Y)m, where C84 is a fullerene, Y is a moiety attached, directly or indirectly, to the C84 fullerene, where m is in the range of 1 to 30, and Y is selected from the group consisting of lipophilic moieties, hydrophilic moieties, amphiphilic moieties, free radical scavenging moieties, or bio-site specific moieties.

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