Hybrid contact lenses prepared with expansion controlled polymeric materials
First Claim
1. A hybrid contact lens blank, comprising:
- a rigid center portion;
a skirt portion disposed about the center portion; and
a diluent dispersed within the skirt portion, wherein the diluent comprises at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide.
1 Assignment
0 Petitions
Accused Products
Abstract
A hybrid contact lens includes a substantially rigid center portion and a substantially flexible skirt portion connected to the center portion. The skirt portion is formed using xerogels compatible with diluents comprising at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide. These diluents are formulated to function as a stand-in for water in the xerogel polymer, allowing the xerogel to form and bond to the rigid center portion in its fully expanded state. Upon hydration of the hybrid lens, substantially little dimensional change, and thus substantially little distortion, is obtained in the skirt portion. The diluents of the present invention further preserve the mechanical integrity of the xerogel, allowing the xerogel to be machined to final shape, improving the dimensional tolerances which can be achieved in the hybrid lens.
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Citations
48 Claims
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1. A hybrid contact lens blank, comprising:
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a rigid center portion; a skirt portion disposed about the center portion; and a diluent dispersed within the skirt portion, wherein the diluent comprises at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A xerogel polymer composition, comprising:
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a vinyl amide recurring unit; a polysiloxanylalkyl acrylate or methacrylate recurring unit; a fluorine containing recurring unit; a styrene containing recurring unit; a crosslinking unit; and a diluent comprising at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22)
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23. A xerogel polymer composition, comprising:
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a polymer; and a diluent dispersed within the polymer, wherein the diluent comprises at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide, wherein the amount of diluent is selected so that upon substantially full hydration, the xerogel composition undergoes a linear expansion of less than approximately 8%. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A hybrid contact lens, comprising:
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a rigid center portion, comprising; an acrylate recurring unit; a styrene containing recurring unit; a silicon containing recurring unit; a fluorine containing recurring unit; a cross-linking unit; and an annular skirt portion coupled to the center portion at a junction between an outer peripheral edge of the center portion and an inner edge of the annular skirt portion, wherein the skirt portion comprises; a vinyl amide recurring unit; a polysiloxanylalkyl acrylate or methacrylate recurring unit; a fluorine containing recurring unit; a styrene containing recurring unit; a cross-linking unit; and a diluent dispersed within the skirt portion, wherein the diluent comprises at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42)
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43. A method for preparing a hybrid contact lens, the method comprising:
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providing a substantially rigid center portion; forming a peripheral skirt portion in the presence of the center portion, the skirt portion comprising a xerogel polymer and a diluent comprising at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide; and machining at least the skirt portion to a selected shape while the diluent is present in the skirt portion. - View Dependent Claims (44, 45, 46, 47, 48)
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Specification