Polyviologen boronic acid quenchers for use in analyte sensors
First Claim
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1. A polyviologen compound comprising two or more viologen moieties, wherein each viologen moiety includes at least two boronic acid functional groups, and wherein the polyviologen compound comprises a coupling group.
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Abstract
The invention relates to a class of glucose-responsive, polyviologen boronic acid quenchers that may be used in combination with fluophores to achieve real-time measurement of glucose levels in vivo.
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Citations
28 Claims
- 1. A polyviologen compound comprising two or more viologen moieties, wherein each viologen moiety includes at least two boronic acid functional groups, and wherein the polyviologen compound comprises a coupling group.
- 19. The compound:
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27. A composition of matter, comprising a fluorophore that is susceptible to quenching by a viologen, a polyviologen derived from a 3,3′
- dipyridyl intermediate comprising two or more viologen moieties, wherein each viologen moiety includes at least two boronic acid functional groups, and a glucose permeable polymer matrix.
- View Dependent Claims (28)
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