Controlled needle-free transport
First Claim
1. A needle-free transdermal transport device for transferring a substance across a surface of a biological body comprising:
- a reservoir for storing the substance;
a nozzle in fluid communication with the reservoir; and
a controllable Lorentz-force electromagnetic actuator in communication with the reservoir, the actuator comprising;
a stationary magnet assembly providing a magnetic field; and
a coil assembly, slidably disposed with respect to the magnet assembly, the coil assembly receiving an electrical input and generating in response a force corresponding to the received input, the force resulting from interaction of an electrical current within the coil assembly and the magnetic field and causing a needle-free transfer of the substance between the reservoir and the biological body; and
a servo-controller in electrical communication with the controllable electromagnetic actuator, the servo-controller providing the electrical input, the force generated within the coil assembly being dynamically variable during injection of the substance according to variations in the received electrical input.
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Accused Products
Abstract
A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.
61 Citations
16 Claims
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1. A needle-free transdermal transport device for transferring a substance across a surface of a biological body comprising:
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a reservoir for storing the substance; a nozzle in fluid communication with the reservoir; and a controllable Lorentz-force electromagnetic actuator in communication with the reservoir, the actuator comprising; a stationary magnet assembly providing a magnetic field; and a coil assembly, slidably disposed with respect to the magnet assembly, the coil assembly receiving an electrical input and generating in response a force corresponding to the received input, the force resulting from interaction of an electrical current within the coil assembly and the magnetic field and causing a needle-free transfer of the substance between the reservoir and the biological body; and a servo-controller in electrical communication with the controllable electromagnetic actuator, the servo-controller providing the electrical input, the force generated within the coil assembly being dynamically variable during injection of the substance according to variations in the received electrical input. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A needle-free transdermal transport device for transferring a substance across a surface of a biological body comprising:
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Lorentz-force electromagnetic actuator means for applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing transfer of the substance across the surface of the body; means for sensing during transfer of the substance a physical property; means for varying the applied electrical input responsive to the sensed physical property to produce a corresponding variation in the applied mechanical force; and servo-controller means for controlling the electromagnetic actuator, the servo-controller means being in electrical communication with the electromagnetic actuator, the servo-controller providing the electrical input, the force generated with the electromagnetic actuator being dynamically variable during injection of the substance according to variations in the received electrical input.
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Specification