Device for dispensing substances

• US 7,833,192 B2
• Filed: 11/23/2004
• Issued: 11/16/2010
• Est. Priority Date: 03/02/2004
• Status: Active Grant

• Current Assignee: Dragerwerk AG & Company KGaA (FPS Vermögensverwaltung GmbH)
• Original Assignee: Dragerwerk AG
• Inventors: Blumenthal, Tilman von, Koch, Jochim, Kullik, Götz
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): HOLLOWAY, IAN KNOBEL
• Application Number:
  US10/995,910
• Publication Number:
  US 20050197622A1
• Time in Patent Office: 2,184 Days
• Field of Search: 604/82, 604/89, 604/151, 424/402, 424/427, 424/405, 424/400, 424/424, 424/426, 424/440, 424/473, 222/212, 222/83, 222/94, 428/144, 428/147, 428/402, 422/65, 422/100
• US Class Current: 604/96.01
• CPC Class Codes: A61J 3/002 Compounding apparatus specially for enteral or parenteral nutritive solutions bottling liquids B67C
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/141 with capillaries for restricting fluid flow
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: B01F 33/84 Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
• CPC Class Codes: B01F 35/8311 with means for controlling the motor driving the pumps or the other dispensing mechanisms

Abstract

A drug dispensing system is provided that may be used universally and in which medical substances can be mixed with a carrier solution (13) in a simple manner. The device and system have a dispensing module (6) for medical substances and a hydrophilic nonwoven (14) with a carrier solution (13). The emission area of substance discharge openings (21, 22, 23, 24) of the dispensing module (6) are directed toward the nonwoven (14).

Claims

1. A drug dispensing system, comprising:

a dispensing module for dispensing medical substances, the dispensing module having a discharge opening;

a mixing channel comprising a hydrophilic nonwoven extending along a length thereof, said hydrophilic nonwoven having capillaries defining a fluid exchange interface, said mixing channel receiving a carrier solution via said hydrophilic nonwoven, wherein an area of emission of the medical substance from said discharge opening of said dispensing module is directed toward the nonwoven such that said hydrophilic nonwoven receives medical substances from said dispensing module, said capillaries of said hydrophilic nonwoven delivering medical substances to said carrier solution at said fluid exchange interface in said mixing channel such that said carrier solution mixes with said medical substances to form a medical fluid.

2. A drug dispensing system in accordance with claim 1, wherein said dispensing module comprises a particle dispensing means.

3. A drug dispensing system in accordance with claim 1, wherein said dispensing module comprises a drop dispenser means.

4. A drug dispensing system in accordance with claim 1, wherein said dispensing module comprises a parallel dispenser with a plurality of discharge openings located in an area of emission directed toward the nonwoven for dispensing different medical substances.

5. A drug dispensing system in accordance with claim 4, wherein said parallel dispenser is designed for the simultaneous and independent dispensing of drops of different substances and particles of different substances.

6. A drug dispensing system in accordance with claim 1, wherein said carrier solution is one of a sodium chloride solution, a glucose solution, a Ringer'"'"'s solution, a fat emulsion or a nutrient solution.

7. A drug dispensing system in accordance with claim 1, said nonwoven comprises glass fibers, polyethylene with hydrophilic plasma coating, cellulose, polyolefin or polyester.

8. A drug dispensing system in accordance with claim 1, further comprising a delivery means for pumping the carrier solution into an infusion line and for setting a pressure such that a pressure difference between a barometric pressure in the emission area of the substance discharge and a hydrostatic pressure in said nonwoven is less than a maximum capillary pressure, said delivery means being provided on the outflow side of the nonwoven.

20. A drug dispensing system in accordance with claim 1, further comprising:

a carrier solution container having a reservoir of said carrier solution, said carrier solution container being located upstream of said mixing channel, said mixing channel having a hydrophilic wick integrally connected thereto, said hydrophilic wick extending into said reservoir of said carrier solution;

a mixing chamber comprising said dispensing module and said mixing channel;

a delivery means for transferring said carrier solution from said carrier solution container through said mixing channel via said hydrophilic wick and said hydrophilic nonwoven to an infusion line such that air does not enter said mixing channel from said mixing chamber via said capillaries of said nonwoven.

9. A process for dispensing liquid or particulate substances with a dispensing module, the process comprising the steps of:

providing a mixing channel having a hydrophilic nonwoven extending along a length thereof, said hydrophilic nonwoven having a capillary structure defining a fluid exchange interface of said mixing channel;

providing a reservoir of carrier solution upstream of said mixing channel;

directing an emission area of substance discharge openings of a dispensing module toward the nonwoven such that said capillary structure of said nonwoven receives substances from said dispensing module;

passing carrier solution from said reservoir of carrier solution to said mixing channel via said hydrophilic nonwoven such that said carrier solution receives said substances at said fluid exchange interface to form a medical fluid;

delivering said medical fluid intravenously to a patient.

10. A process in accordance with claim 9, wherein a delivery means for delivering the carrier solution is arranged downstream of the nonwoven.

11. A process in accordance with claim 9, wherein a pressure difference between the barometric pressure in the emission area of the substance discharge openings and the hydrostatic pressure in the nonwoven is set such that such pressure is lower than the maximum capillary pressure, the maximum capillary pressure being obtained from the pairing of the nonwoven and the carrier solution.

12. A drug dispensing system, comprising:

a dispensing module for dispensing medical substances, the dispensing module having a plurality of discharge openings;

a mixing channel having a hydrophilic nonwoven extending along a length thereof, said hydrophilic nonwoven having a capillary structure, said capillary structure defining a fluid exchange surface of said mixing channel;

a carrier solution container with carrier solution in said container and taken up by said nonwoven, said carrier solution container being located upstream of said mixing channel, said substance discharge openings of said dispensing module each having an area of emission directed toward said nonwoven in a region in which said carrier solution is taken up;

a pump transferring carrier solution from said carrier solution container through said mixing channel via said hydrophilic nonwoven such that said carrier solution mixes with said medical substances at said fluid exchange interface to form a medical fluid mixture, said pump transferring said medical fluid mixture from said mixing channel to a patient.

13. A drug dispensing system in accordance with claim 12, wherein said dispensing module comprises a particle dispensing means for dispensing substance particles at least at one of said substance discharge openings.

14. A drug dispensing system in accordance with claim 12, wherein said dispensing module comprises a drop dispenser means for dispensing liquid substance at least at one of said substance discharge openings.

15. A drug dispensing system in accordance with claim 12, wherein said dispensing module comprises a parallel dispenser means corresponding with said plurality of discharge openings for dispensing different medical substances.

16. A drug dispensing system in accordance with claim 15, wherein said parallel dispenser means is for the simultaneous and independent dispensing of drops of different substances and/or particles of different substances.

17. A drug dispensing system in accordance with claim 12, wherein said carrier solution is one of a sodium chloride solution, a glucose solution, a Ringer'"'"'s solution, a fat emulsion or a nutrient solution.

18. A drug dispensing system in accordance with claim 12, wherein said nonwoven comprises glass fibers, polyethylene with hydrophilic plasma coating, cellulose, polyolefin or polyester.

19. A drug dispensing system in accordance with claim 12, wherein said pump transfers said medical fluid mixture to the patient through an infusion line, said pump transferring said carrier solutions from said carrier solution container through said mixing channel to said infusion line such that air does not enter said mixing channel via said capillary structure of said nonwoven, said pump maintaining a pressure in said mixing channel such that a pressure difference between a barometric pressure in the emission area of the substance discharge and a hydrostatic pressure in said nonwoven is less than a maximum capillary pressure.