Bioabsorbable polymeric medical device

• US 7,833,260 B2
• Filed: 07/20/2007
• Issued: 11/16/2010
• Est. Priority Date: 07/20/2006
• Status: Expired due to Fees

• Current Assignee: OrbusNeich Medical Pte Ltd
• Original Assignee: Orbusneich Medical Incorporated (Orbusneich Medical)
• Inventors: Cottone, Robert J., Ye, Shusheng, Pazienza, John
• Primary Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US11/781,229
• Publication Number:
  US 20080051873A1
• Time in Patent Office: 1,215 Days
• Field of Search: 623/1.12, 623/1.15, 623/1.1, 623/1.17, 623/1.18, 623/1.19, 623/1.2, D25/155
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91566 connected trough to trough
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/91583 by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0057 stretchable
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0039 H-shaped
• CPC Class Codes: A61F 2230/0054 : V-shaped
• CPC Class Codes: A61F 2230/0058 : X-shaped
• CPC Class Codes: A61F 2250/0098 : radio-opaque, e.g. radio-opaque markers

Abstract

In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.

Claims

1. An expandable biodegradable tubular scaffold comprising:

a plurality of biodegradable first meanders forming an interconnected mesh, said mesh extending circumferentially about a longitudinal axis;

wherein each of said biodegradable first meanders are manufactured from a racemic polymer which crystallizes under the strain of expansion of said tubular scaffold;

a plurality of biodegradable second meanders, each of said second meanders being separate from another, and each extending circumferentially about said longitudinal axis in a single plane, said second meanders being nest in, and interconnected to, said first meanders,

and a locking means, wherein the locking means is a two-part portion of one or different meandering strut elements located at proximal and distal ends of the scaffold and wherein the locking means comprises a cantilever arm hooking an oppositely shaped end piece of the scaffold.

2. The scaffold of claim 1 wherein said first meanders are generally parallel to said longitudinal axis.

3. The scaffold of claim 1 wherein said first meanders are generally diagonal to said longitudinal axis.

4. The scaffold of claim 1 wherein said first meanders are generally orthogonal to said longitudinal axis.

5. The scaffold of claim 1 wherein said first meanders are concentric about said longitudinal axis.

6. The scaffold of claim 1 wherein said second meanders are made of a material which crystallizes when said tube is in its expanded state, but does not substantially crystallize in its unexpanded state.

7. The scaffold of claim 1 wherein said first meanders form a strut pattern that is sinusoidal when said tube is in an expanded form.

8. The scaffold of claim 7 wherein said second meanders form a strut pattern that is substantially non-sinusoidal when said tube is in an expanded form.

9. The scaffold of claim 1 wherein said first meanders form a strut pattern that extends from said proximal open end to said distal open end of said tube.

10. The scaffold of claim 9 wherein said second meanders form a strut pattern that is found at said proximal open end and said distal open end.

11. The scaffold of claim 10 wherein said second meanders form a strut pattern that is further found between said proximal open end and said distal open end.

12. The scaffold of claim 9 wherein said second meanders form a pattern that is found between said proximal open end and said distal open end but not at the proximal open end or said distal open end.