Medication delivery system and monitor

• US 7,837,647 B2
• Filed: 03/06/2007
• Issued: 11/23/2010
• Est. Priority Date: 12/19/2001
• Status: Expired due to Term

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: Bowman, Leif N., Talbot, Cary Dean, Estes, Mark C., Malave, Denetta
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): MATNEY, BROOKE MARIE
• Application Number:
  US11/714,552
• Publication Number:
  US 20070287985A1
• Time in Patent Office: 1,358 Days
• Field of Search: 604/65, 604/66, 604/67, 607/60
• US Class Current: 604/65
• CPC Class Codes: A61M 2005/1405 Patient controlled analgesia [PCA]
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2005/14296 Pharmacokinetic models
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2209/01 Remote controllers for specific apparatus
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16
• CPC Class Codes: A61M 5/14 Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Systems and methods for the delivery and monitoring of a medication, such as insulin, to a recipient are provided. An exemplary feature-rich system comprises an infusion pump with a control system for controlling medication delivery by the infusion pump and a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump. Estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile. In other embodiments, the control system comprises a suspend function for temporarily suspending medication delivery by the infusion pump, an alarm profile function for programming a variable alarm volume of the alarm and a simplified menu for controlling the dual wave bolus delivery function.

Claims

1. A system for delivering medication, comprising:

an infusion pump;

a control system for controlling medication delivery by the infusion pump; and

a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump, wherein estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile and wherein;

the setting profile for at least one of the one or more settings includes a value which varies according to a schedule; and

the setting profile is entered with a graphical programming interface that includes a series of discrete divisions, each having a setting value and the setting profile is programmed by adjusting the setting value of selected ones of the discrete divisions in sequence such that any setting value of each prior discrete division is unchanged and any setting value of each subsequent discrete division is automatically adjusted to the value of the selected ones of the discrete divisions.

2. The system of claim 1, wherein the control system controls medication delivery according to one or more medication delivery profiles.

3. The system of claim 2, wherein the one or more medication delivery profiles comprises the appropriate amount of medication estimated by the bolus estimator.

4. The system of claim 1, wherein the one or more settings are selected from the group including target blood glucose, carbohydrate ratio and insulin sensitivity.

5. The system of claim 1, wherein the control system is programmed to control medication delivery from a source selected from the group including an RF programmer, a communication station and direct input.

6. The system of claim 1, wherein the bolus estimator estimates the appropriate amount of medication based upon one or more event markers stored in a memory.

7. The system of claim 6, wherein the one or more event markers track events which affect medication need.

8. The system of claim 6, wherein the one or more event markers are selected from the group comprising a meal marker, a snack marker, a high blood glucose marker, a low blood glucose marker, an exercise marker, an illness marker and a stress marker.

10. The system of claim 1 or claim 9, the system further comprising an alarm to indicate status of infusion pump, and wherein the control system includes an alarm profile function for programming a variable alarm volume of the alarm.

11. The system of claim 10, wherein the alarm profile function varies the variable alarm volume according to a schedule.

12. The system of claim 10, wherein the variable alarm volume is set by the user.

9. A system for delivering medication, comprising:

an infusion pump;

a control system for controlling medication delivery by the infusion pump; and

a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump, wherein the bolus estimator estimates the appropriate amount of medication based upon one or more event markers stored in a memory and further wherein estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile and

the setting profile for at least one of the one or more settings includes a value which varies according to a schedule; and

the setting profile is entered with a graphical programming interface that includes a series of discrete divisions, each having a setting value and the setting profile is programmed by adjusting the setting value of selected ones of the discrete divisions in sequence such that any setting value of each prior discrete division is unchanged and any setting value of each subsequent discrete division is automatically adjusted to the value of the selected ones of the discrete divisions.

13. A method of delivering medication, comprising the steps of:

controlling medication delivery by an infusion pump with a control system;

estimating an appropriate amount of medication for delivery by the control system with the infusion pump, wherein estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile; and

wherein;

the setting profile for at least one of the one or more settings includes a value which varies according to a schedule; and

the setting profile is entered with a graphical programming interface that includes a series of discrete divisions, each having a setting value and the setting profile is programmed by adjusting the setting value of selected ones of the discrete divisions in sequence such that any setting value of each prior discrete division is unchanged and any setting value of each subsequent discrete division is automatically adjusted to the value of the selected ones of the discrete divisions.

14. The method of claim 13, wherein the step of controlling includes controlling medication delivery according to one or more medication delivery profiles.

15. The method of claim 14, wherein the one or more medication delivery profiles includes the appropriate amount of medication estimated by a bolus estimator.

16. The method of claim 13, wherein the one or more settings are selected from the group including target blood glucose, carbohydrate ratio and insulin sensitivity.

17. The method of claim 13, wherein the control system is programmed to control medication delivery from a source selected from the group including an RF programmer, a communication station and direct input.

18. The method of claim 13, wherein the estimator estimates the appropriate amount of medication based upon one or more event markers stored in a memory.

19. The method of claim 18, wherein the one or more event markers track events which affect medication need.

20. The method of claim 18, wherein the one or more event markers are selected from the group comprising a meal marker, a snack marker, a high blood glucose marker, a low blood glucose marker, an exercise marker, an illness marker and a stress marker.

22. The method of claim 13 or 21, further comprising the steps of:

using an alarm to indicate status of the infusion pump; and

activating the alarm according to an alarm profile function when a potentially harmful condition occurs in controlling medication delivery, wherein the alarm profile function includes programming a variable alarm volume of the alarm.

23. The method of claim 22, wherein the alarm profile function varies the variable alarm volume according to a schedule.

24. The method of claim 22, wherein the variable alarm volume is set by the user.

21. A method of delivering medication, comprising the steps of:

controlling medication delivery by an infusion pump with a control system;

estimating an appropriate amount of medication for delivery by the control system with the infusion pump, wherein estimating the appropriate amount of medication for delivery is;

based upon one or more settings which each vary according to a setting profile;

based upon one or more event markers stored in a memory; and

wherein

the setting profile for at least one of the one or more settings includes a value which varies according to a schedule; and

the setting profile is entered with a graphical programming interface that includes a series of discrete divisions, each having a setting value and the setting profile is programmed by adjusting the setting value of selected ones of the discrete divisions in sequence such that any setting value of each prior discrete division is unchanged and any setting value of each subsequent discrete division is automatically adjusted to the value of the selected ones of the discrete divisions.