Accelerated healing with intraoperative combination of suture and autogenous blood components

• US 7,837,708 B2
• Filed: 04/22/2005
• Issued: 11/23/2010
• Est. Priority Date: 04/22/2004
• Status: Active Grant

• Current Assignee: Arthrex Incorporated
• Original Assignee: Arthrex Incorporated
• Inventors: Grafton, R. Donald, Schmieding, Reinhold
• Primary Examiner(s): Ho; (Jackie) Tan-Uyen T
• Assistant Examiner(s): Dornbusch; Dianne
• Application Number:
  US11/112,003
• Publication Number:
  US 20050240225A1
• Time in Patent Office: 2,041 Days
• Field of Search: 606/228, 606/229, 606/230, 606/231, 424/443, 424/444, 424529-534, 427/2.31, 128/898
• US Class Current: 606/228
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00831 Material properties
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective

Abstract

A suture combined intraoperatively with autogenous blood components. At least one strand of suture is placed into a sterile container. Blood obtained from a patient is separated, using a centrifuge, for example, to retrieve certain healing components such as autogenous growth factors, to obtain an autogenous blood suspension. The autogenous blood suspension is added to the sterile container containing the strand of suture. The suture wicks up biologic components of the autogenous blood suspension to produce an enhanced suture. Surgical repairs using the enhanced suture are conducted by suturing a tear to itself or to bone, for example. Post-operatively, the biologic components leach from the suture to accelerate healing of the repair.

Claims

1. A method of suturing comprising:

placing a length of suture into a sterile container;

obtaining an autogenous blood component from a patient by centrifuging the patient'"'"'s blood;

adding an anticoagulant to the autogenous blood component to prevent coagulation of the autogenous blood component and keep the blood component in suspension; and

intraoperatively adding the uncoagulated autogenous blood component to the length of suture into the sterile container to obtain a suture soaked with the autogenous blood component.

2. The method of claim 1, further comprising suturing tissue of the patient using the length of suture soaked with the autogenous blood component.

3. The method of claim 1, wherein the autogenous blood component comprises a growth factor.

4. The method of claim 3, wherein the growth factor is platelet-rich plasma.

5. A surgical suture comprising:

a length of suture prepared for surgical use in a patient in accordance with the method of claim 1, including the step of obtaining an autogenous blood component from the patient by centrifuging the patient'"'"'s blood and adding an anticoagulant to the autogenous blood component to form an anticoagulant added to autogeneous blood material obtained from the patient to form an uncoagulated autogenous blood material, the suture being impregnated with the uncoagulated autogenous blood material intraoperatively and prior to surgical use.

6. A surgical method comprising:

providing at least one strand of suture into a container;

obtaining an autogenous blood suspension from a patient by centrifuging the patient'"'"'s blood;

adding an anticoagulant to the autogenous blood suspension to prevent coagulation of the autogenous blood suspension and keep blood in suspension;

subsequently, adding the uncoagulated autogenous blood suspension to the at least one strand of suture in the container to obtain a soaked suture; and

suturing tissue of the patient using the soaked suture combined with the autogenous blood suspension.

7. The method of claim 6, wherein the autogenous blood suspension includes a component selected from the group consisting of autogenous growth factors, hyaluronic acid, antiseptics, antibiotics, and vitamins.

8. The method of claim 6, wherein the autogenous blood suspension comprises platelet-rich plasma.

9. The method of claim 6, wherein the at least one strand of suture comprises a material selected from the group consisting of collagen, surgical gut, silk, cotton, polyolefins, polyamides, polyesters, polyglycolic acid and glycolide-lactide copolymer.