Reduced length tissue shaping device

• US 7,837,728 B2
• Filed: 12/19/2003
• Issued: 11/23/2010
• Est. Priority Date: 12/19/2003
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Aronson, Nathan, Gordon, Lucas, Nieminen, Gregory, Beget, Garrett, Reuter, David
• Primary Examiner(s): Matthews; William H.
• Application Number:
  US10/742,519
• Publication Number:
  US 20050137685A1
• Time in Patent Office: 2,531 Days
• Field of Search: 623 236- 238
• US Class Current: 623/2.36
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape

Abstract

One aspect of the invention is a method of treating mitral valve regurgitation in a patient. The method includes the steps of delivering a tissue shaping device to the patient'"'"'s coronary sinus in an unexpanded configuration within a catheter having an outer diameter no more than nine or ten french, with the tissue shaping device including a connector disposed between a distal expandable anchor comprising flexible wire and a proximal expandable anchor comprising flexible wire, the device having a length of 60 mm or less; and deploying the device to reduce mitral valve regurgitation, such as by anchoring the distal expandable anchor by placing the distal expandable anchor flexible wire in contact with a wall of the coronary sinus, e.g., by permitting the distal expandable anchor to self-expand or by applying an actuating force to the distal expandable anchor and possibly locking the distal expandable anchor after performing the applying step. The invention also includes a device for performing the method.

Claims

1. A method of treating mitral valve regurgitation in a patient, the method comprising:

delivering a tissue shaping device to the patient'"'"'s coronary sinus in an unexpanded configuration within a catheter having an outer diameter no more than ten french, the tissue shaping device comprising a connector disposed between a distal expandable anchor comprising flexible wire and a proximal expandable anchor comprising flexible wire, the device having a length of 60 mm or less;

anchoring the distal anchor in the coronary sinus by expanding the distal anchor to an expanded configuration;

locking the distal anchor in the expanded configuration by moving a first locking element relative to a second locking element to engage the first and second locking elements in a locked configuration;

applying a proximally directed force on the distal expandable anchor through the connector by moving the unexpanded proximal anchor proximally with respect to the coronary sinus, wherein anchoring the distal anchor in the coronary sinus occurs before applying the proximally directed force; and

reducing mitral valve regurgitation while moving the unexpanded proximal anchor proximally with respect to the coronary sinus.

2. The method of claim 1 wherein the delivering step comprises delivering the tissue shaping device to the patient'"'"'s coronary sinus in an unexpanded configuration within a catheter having an outer diameter no more than nine french.

3. The method of claim 1 wherein anchoring the distal expandable anchor comprises permitting the distal expandable anchor to self-expand.

4. The method of claim 1 wherein the anchoring step comprises applying an actuating force to the distal expandable anchor.

5. The method of claim 4 wherein the anchoring step further comprises locking the distal expandable anchor after applying the actuating force.

6. The method of claim 1 wherein anchoring the distal expandable anchor comprises anchoring the distal expandable anchor with an anchoring force of at least one pound.

7. The method of claim 6 wherein anchoring the distal expandable anchor comprises anchoring the distal expandable anchor with an anchoring force of at least two pounds.

8. The method of claim 1 wherein the step of applying a proximally directed force comprises applying a proximally directed force on the distal anchor from outside the patient.

9. The method of claim 1 further comprising anchoring the proximal anchor.

10. The method of claim 9 wherein the step of anchoring the proximal anchor is performed after the step of applying a proximally directed force on the distal expandable anchor.

11. The method of claim 9 wherein the step of anchoring the proximal anchor comprises expanding the proximal anchor.

12. The method of claim 11 wherein anchoring the proximal anchor comprises permitting the proximal expandable anchor to self-expand.

13. The method of claim 11 wherein anchoring the proximal anchor comprises applying an actuating force to the proximal expandable anchor.

14. The method of claim 1 wherein the delivering step comprises delivering the tissue shaping device to the coronary sinus in an unexpanded configuration in which none of the distal expandable anchor flexible wire extends proximally along the connector within the catheter.

15. The method of claim 1 wherein the delivering step comprises delivering the tissue shaping device to the coronary sinus in an unexpanded configuration in which at least a portion of the distal expandable anchor flexible wire extends proximally along the connector within the catheter.

16. The method of claim 1 wherein the distal expandable anchor further comprises a distal expandable anchor flexible wire connection substantially limiting proximal and distal movement of the connection with respect to the distal expandable anchor, the delivering step comprising delivering the tissue shaping device to the coronary sinus in an unexpanded configuration in which at least a portion of the distal expandable anchor flexible wire extends from the connection proximally along the connector within the catheter.

17. The method of claim 1 wherein the distal expandable anchor further comprises a distally and proximally movable distal expandable anchor flexible wire connection, the delivering step comprising delivering the tissue shaping device to the coronary sinus in an unexpanded configuration in which at least a portion of the distal expandable anchor flexible wire extends proximally along the connector within the catheter.

18. The method of claim 17 wherein anchoring the distal anchor comprises moving the connection distally to actuate the distal expandable anchor.

19. The method of claim 18 wherein anchoring the distal anchor further comprises locking the distal expandable anchor after performing the moving step.

20. The method of claim 1 wherein the distal expandable anchor further comprises a distally and proximally movable distal expandable anchor flexible wire connection, the delivering step comprising delivering the tissue shaping device to the coronary sinus in an unexpanded configuration in which at least a portion of the distal expandable anchor flexible wire extends distally along the connector within the catheter.

21. The method of claim 20 wherein anchoring the distal anchor comprises moving the connection distally to actuate the distal expandable anchor.

22. The method of claim 21 wherein anchoring the distal anchor further comprises locking the distal expandable anchor after performing the moving step.