Device for the extravascular recirculation of liquid in body cavities

• US 7,842,002 B2
• Filed: 11/12/2003
• Issued: 11/30/2010
• Est. Priority Date: 11/12/2002
• Status: Expired due to Fees

• Current Assignee: Theranova, Llc
• Original Assignee: Ross E. Mantle
• Inventors: Mantle, Ross E.
• Primary Examiner(s): Zalukaeva; Tatyana
• Assistant Examiner(s): Wiest; Philip R
• Application Number:
  US10/523,857
• Publication Number:
  US 20060161107A1
• Time in Patent Office: 2,575 Days
• Field of Search: 604/4.01, 604/6.09, 604/6.15, 604/6.16, 604/317, 604/319, 604/6.11, 604/6.13, 422 44- 48
• US Class Current: 604/6.11
• CPC Class Codes: A61F 2007/0069 with return means
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/1686 by heat
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/285 Catheters therefor
• CPC Class Codes: A61M 1/32 Oxygenators without membranes
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/3687 Chemical treatment A61M1/3675 takes precedence
• CPC Class Codes: A61M 2025/0031 characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment
• CPC Class Codes: A61M 2025/0037 characterized by lumina being arranged side-by-side
• CPC Class Codes: A61M 2205/36 related to heating or cooling
• CPC Class Codes: A61M 2230/50 Temperature
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves
• CPC Class Codes: A61M 3/0202 with electronic control means or interfaces
• CPC Class Codes: A61M 3/0229 Devices operating in a closed circuit, i.e. recycling the irrigating fluid
• CPC Class Codes: A61M 3/0258 by means of electric pumps
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media

Abstract

Biocompatible liquid is pumped into a body cavity (eg. subarachnoid space, peritoneum, mediastinum, pleural space) by means of one pump and removed from it by means a second pump, preferably via a double-barreled catheter is used for insertion and removal of the liquid. An optional secondary catheter removes liquid from a distal area of the body cavity. Temperature and pressure are sensed within the cavity and can be controlled by adjusting liquid flow rates. While outside the body, the liquid can be ultraviolet-sterilized, foam fractionated to remove contaminants, oxygenated and pH balanced, cooled or warmed, and augmented with exogenous liquid that may contain drugs.

Claims

1. Apparatus for modulating introduction and removal of a liquid within a cavity of a patient'"'"'s body, the cavity comprising a cavity outside of blood vessels, the apparatus comprising:

a catheter configured for insertion into the cavity and introduction and removal of liquid from the cavity;

one or more sensors positionable in the patient'"'"'s body so as to sense a condition of liquid in the cavity; and

a controlled pumping system operatively coupled to both the catheter and the one or more sensors, the controlled pumping system configured to control introduction and removal of liquid from the cavity so as to maintain a selected liquid condition value.

2. The apparatus of claim 1, the catheter comprising a first lumen for introducing liquid into the cavity and a second lumen for removing fluid from the cavity.

3. The apparatus of claim 1, wherein the one or more sensors are positioned on the catheter.

4. The apparatus of claim 1, wherein the one or more sensors are positioned separate from the catheter and positionable at a location separate from the catheter.

5. The apparatus of claim 1 wherein the condition is liquid pressure.

6. The apparatus of claim 1 wherein the condition is liquid temperature.

7. The apparatus of claim 1 wherein the catheter comprises a dual lumen catheter.

8. The apparatus of claim 1, further comprising a first receptacle for storing liquid to be introduced into the patient'"'"'s cavity and a second receptacle for collecting liquid removed from the patient'"'"'s cavity.

9. The apparatus of claim 8, wherein the first receptacle and second receptacle are coupled so as to allow recirculation of liquid.

10. The apparatus of claim 1 further comprising a second catheter configured for removal of liquid from the cavity.

11. A feedback-controlled apparatus for introduction and removal of a liquid within a cavity of a patient'"'"'s body, the cavity comprising a cavity outside of blood vessels, the apparatus comprising:

a catheter configured for insertion into the cavity and introduction and removal of liquid from the cavity;

one or more sensors positionable so as to sense a biological parameter of a patient'"'"'s body; and

a controlled pumping system operatively coupled to both the catheter and the one or more sensors, the controlled pumping system configured to modulate a property of the liquid in response to signals received from the one or more sensors and to maintain the biological parameter of the patient'"'"'s body within a selected range.

12. The apparatus of claim 11, wherein the property of the liquid comprises rate of introduction or removal from the cavity.

13. The apparatus of claim 11, wherein the property of the liquid comprises contamination level, concentration, oxygenation, pH, or chemical agent or drug content.

14. The apparatus of claim 11 wherein the catheter comprises a dual lumen catheter.

15. A method of maintaining a liquid condition parameter within a body cavity other than a blood vessel within a patient'"'"'s body, the method comprising:

pumping liquid into the cavity;

pumping liquid out of the cavity;

monitoring a parameter of liquid within the cavity from a sensor disposed within the patient'"'"'s body; and

controlling at least one of liquid temperature, liquid pressure, and liquid flow rate in response to a liquid condition value measured in the monitoring step.

16. The method of claim 15 wherein the monitoring step comprises monitoring temperature of liquid within the cavity.

17. The method of claim 15 wherein the monitoring step comprises monitoring pressure of liquid within the cavity.

18. The method of claim 15 wherein the steps of pumping liquid into the cavity and pumping liquid out of the cavity comprises pumping liquids into and out of the cavity through a single catheter.

19. The method of claim 18 wherein the catheter comprises a dual lumen catheter.

20. The method of claim 15 wherein the step of pumping liquid out of the cavity comprises pumping liquid out of the cavity through an outflow catheter disposed remote from an inflow catheter through which liquid is pumped into the cavity.