Assay plates, reader systems and methods for luminescence test measurements
First Claim
1. A multi-well plate comprising a plate top having plate top openings and a plate bottom mated to said plate top to define wells of said multi-well plate, said plate bottom comprising a substrate having a top surface with electrodes patterned thereon and a bottom surface with electrical contacts patterned thereon, wherein said electrodes and contacts are patterned to define two or more independently addressable sectors of two or more jointly addressable assay wells, each sector comprising two or more wells with:
- (a) jointly addressable working electrodes on said top surface of said substrate, wherein each of said working electrodes is electrically connected with each other and connected to at least a first of said electrical contacts; and
(b) jointly addressable counter electrodes on said top surface of said substrate, wherein each of said counter electrodes is electrically connected with each other, but not with said working electrodes, and connected to at least a second of said electrical contacts.
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Accused Products
Abstract
Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
134 Citations
29 Claims
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1. A multi-well plate comprising a plate top having plate top openings and a plate bottom mated to said plate top to define wells of said multi-well plate, said plate bottom comprising a substrate having a top surface with electrodes patterned thereon and a bottom surface with electrical contacts patterned thereon, wherein said electrodes and contacts are patterned to define two or more independently addressable sectors of two or more jointly addressable assay wells, each sector comprising two or more wells with:
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(a) jointly addressable working electrodes on said top surface of said substrate, wherein each of said working electrodes is electrically connected with each other and connected to at least a first of said electrical contacts; and (b) jointly addressable counter electrodes on said top surface of said substrate, wherein each of said counter electrodes is electrically connected with each other, but not with said working electrodes, and connected to at least a second of said electrical contacts. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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Specification