Electrotransport device having an integrally molded reservoir housing

• US 7,844,326 B2
• Filed: 12/20/2002
• Issued: 11/30/2010
• Est. Priority Date: 12/20/2001
• Status: Expired due to Fees

• Current Assignee: ALZA Corporation (Johnson & Johnson)
• Original Assignee: ALZA Corporation (Johnson & Johnson)
• Inventors: Dent, Wanda Faye, Grace, Michael Joseph, Gyory, J. Richard
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): KOHARSKI, CHRISTOPHER
• Application Number:
  US10/327,328
• Publication Number:
  US 20030199807A1
• Time in Patent Office: 2,902 Days
• Field of Search: 604/20, 604/501, 4351735-1767, 204/450, 439/86, 439 89- 91, 439/180, 439/278, 439/909, 600/372, 600/394, 607/120
• US Class Current: 604/20
• CPC Class Codes: A61N 1/0436 Material of the electrode
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir

Abstract

This invention relates to an electrotransport device, which incorporates a conductive element within the reservoir housing of the device, which permits electrical communication from within the housing to outside of the housing without the use of opening, which require various methods of sealing the openings against leaks and moisture.

Claims

1. A reservoir housing for an iontophoretic drug delivery device comprising:

a cavity and an interior and exterior surface;

said reservoir housing at least partially formed of a non-conductive material; and

a monolithic conductive element disposed within a portion of said reservoir housing, the monolithic conductive element integrally formed with the reservoir housing to provide a liquid and moisture tight interface between said conductive element and said reservoir housing.

2. The reservoir housing of claim 1, wherein said conductive element comprises a polymer.

3. The reservoir housing of claim 2, wherein said polymer is selected from the group consisting of polyvinyl chloride, polyethylene terephthalate glycol, polyethylene, polypropylene, -polycarbonate, and acrylics.

4. The reservoir housing of claim 3, wherein said conductive element further comprises carbon black.

5. A reservoir housing for an iontophoretic drug delivery device comprising:

a cavity and an interior and exterior surface;

said reservoir housing at least partially formed of a non-conductive material;

a monolithic conductive element integrally formed within a portion of said reservoir housing to provide a moisture tight interface between said conductive element and said reservoir housing;

said monolithic conductive element further comprising an inner and an outer surface and electrically accessible from both the interior and exterior surfaces of said reservoir housing; and

an electrode disposed within said cavity, said electrode in electrical communication with the inner surface of said monolithic conductive element.

6. A reservoir housing for an iontophoretic drug delivery device comprising:

a cavity and an interior and exterior surface;

said reservoir housing at least partially formed of a non-conductive material;

a monolithic conductive element integrally formed within a portion of said reservoir housing to provide a moisture tight interface between said conductive element and said reservoir housing;

said conductive element further comprising an inner and an outer surface and is electrically accessible from both the interior and exterior surfaces of said reservoir housing; and

wherein said monolithic conductive element further comprises a central cavity and an outwardly extending lip, deformable and insertable through a correspondingly sized opening in an electrical component so that said electrical component can be inserted onto said deformable conductive element and releasably attached to said reservoir housing.

7. The reservoir housing for an iontophoretic drug delivery device of claim 6 wherein said outer surface of said monolithic conductive element is adapted to establish electrical communication with a circuit board when said circuit board is attached to said conductive element.

8. A reservoir housing for an iontophoretic drug delivery device comprising:

a cavity and an interior and exterior surface;

said reservoir housing at least partially formed of a plastic, non-conductive material; and

a plastic conductive element plastically bonded within a portion of said plastic, non-conductive material of said reservoir housing to provide a moisture tight interface between said plastic conductive element and said reservoir housing, said plastic conductive element having a volume resistivity less than about 10,000 ohms-cm.

9. The reservoir housing of claim 8, wherein said conductive element comprises a polymer.

10. The reservoir housing of claim 9, wherein said polymer is selected from the group consisting of polyvinyl chloride, polyethylene terephthalate glycol, polyethylene, polypropylene, -polycarbonate, and acrylics.

11. The reservoir housing of claim 10, wherein said conductive element further comprises carbon black.

12. A reservoir housing for an electrotransport drug delivery device comprising:

a cavity and an interior and exterior surface;

said reservoir housing at least partially formed of a non-conductive material; and

a monolithic conductive element plastically bonded within a portion of said reservoir housing to provide a liquid and moisture impenetrable bond between said conductive element and said reservoir housing;

wherein said reservoir housing further comprises a seal portion to plastically or mechanically interact with said monolithic conductive.

13. A reservoir housing for an iontophoretic drug delivery device comprising:

a cavity and an interior and exterior surface;

said reservoir housing at least partially formed of a plastic, non-conductive material;

a conductive element plastically bonded within a portion of said reservoir housing to provide a moisture tight interface between said conductive element and said reservoir housing; and

an electrode disposed within said cavity and plastically sealed to said reservoir housing, said electrode in electrical communication with a reservoir comprising a drug.