Apparatus and method for separating and concentrating fluids containing multiple components
First Claim
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1. A system for separating and extracting selected fractions from a container, the system comprising:
- a separation system, including;
a first separation member having a first density;
a second separation member having a second density;
a connection member having a wall extending a distance and operably interconnecting said first separation member and said second separation member, the wall having an internal surface defining an internal passage and an external surface;
a first collection face defined by said first separation member;
wherein at least one of said first separation member, said second separation member, or both move along said external surface of said connection member;
wherein a selected fraction is operable to be collected in said first collection face between said first separation member and said second separation member, and accessed with the internal passage.
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Abstract
An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.
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Citations
29 Claims
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1. A system for separating and extracting selected fractions from a container, the system comprising:
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a separation system, including; a first separation member having a first density; a second separation member having a second density; a connection member having a wall extending a distance and operably interconnecting said first separation member and said second separation member, the wall having an internal surface defining an internal passage and an external surface; a first collection face defined by said first separation member; wherein at least one of said first separation member, said second separation member, or both move along said external surface of said connection member; wherein a selected fraction is operable to be collected in said first collection face between said first separation member and said second separation member, and accessed with the internal passage. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A system for separating and extracting selected fractions from a container, the system comprising:
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a separation system, including; a connection member extending a length between a first end and a second end; a first separation member having a first density and moveable along said length of said connection member; a second separation member having a second density different than said first density and fixed near said second end of said connection member; wherein said first separation member is operable to move relative to said second separation member along said length of said connection member; a collection volume defined between a first collection face of said first separation member and a second collection face of said second separation member; wherein a first selected fraction of the selected fractions is operable to be collected from said collection volume. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26)
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27. A system for separating and extracting selected fractions from a container, the system comprising:
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a first separation member and a second separation member interconnected with a connection member having a throughbore through the connection member; a collection volume formed between the first separation member and the second separation member within the container; a tube connected to a connection portion of the connection member an extraction system operably connectable to the tube to extract at least one of the selected fractions from the collection volume; and an extraction port extending through a wall of the container to connect the extraction system to form a passage to the collection volume through the connection member; wherein at least a portion of at least one of the selected fractions is contained within the collection volume after a centrifugation of said first separation member, said second separation member, and said connection member within the container; wherein the tube is substantially permanently connected to said connection portion to allow access to the collection area between the first separation member and the second separation member; wherein said first separation member has a first density and said second separation member has a second density that is higher than said first density; wherein the first separation member has a first collection face and the second separation member has a second collection face; wherein the first collection face is a convex surface having a first angle and the second collection face is a concave surface having a second angle, where the first angle and the second angle are substantially complementary. - View Dependent Claims (28, 29)
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Specification