System and method for modulated surgical procedure irrigation and aspiration

• US 7,846,126 B2
• Filed: 07/14/2003
• Issued: 12/07/2010
• Est. Priority Date: 07/14/2003
• Status: Active Grant

• Current Assignee: Johnson & Johnson Surgical Vision, Inc. (Johnson & Johnson)
• Original Assignee: Abbott Medical Optics Incorporated (Johnson & Johnson)
• Inventors: Steen, Mark E., Kadziauskas, Kenneth E.
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): Price; Nathan R
• Application Number:
  US10/619,088
• Publication Number:
  US 20050054971A1
• Time in Patent Office: 2,703 Days
• Field of Search: 604/22, 604/27, 604/28, 604/32, 604/35, 604/289, 604/290, 604/294, 606/4, 606/107
• US Class Current: 604/28
• CPC Class Codes: A61F 9/00736 Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments A61F9/008 takes precedence
• CPC Class Codes: A61F 9/00745 using mechanical vibrations, e.g. ultrasonic
• CPC Class Codes: A61M 1/75 Intermittent or pulsating suction A61M1/63, A61M1/772 take precedence

Abstract

A method and apparatus for performing modulated fluid delivery and aspiration during a surgical procedure such as phacoemulsification is provided. The method and apparatus include delivering fluid and/or aspirating fluid in a modulated or pulsed manner during a surgical procedure, including applying fluid and/or aspirating fluid in connection with ultrasonic energy at a level and for a time period sufficient to induce transient cavitation. Fluid may be applied and/or aspirated at a timing sequence and duty cycle similar to or different from application of ultrasonic energy delivery.

Claims

1. A method for aspirating fluid from an ocular region during a phacoemulsification procedure, comprising:

aspirating the ocular region by applying a series of modulated differential pressure pulses to the ocular region via a tubing deformation fluid control device configured to selectively deform and substantially close aspiration tubing to provide aspirating fluid from the ocular region, and

delivering modulated ultrasonic energy to the ocular region simultaneous with said aspirating;

wherein selectively deforming and substantially closing aspiration tubing occurs in a controlled nonrandom manner such that fluid is aspirated according to an alterable and controllable nonrandom timing scheme, and further wherein timing of the series of modulated differential pressure pulses is selectively alterable relative to timing of the modulated ultrasonic energy delivery.

2. The method of claim 1, wherein aspirating comprises delivering a series of pulses having a negative pressure differential from ambient for duration less than 100 milliseconds.

3. The method of claim 2, wherein said negative pressure differential pulses are interspersed by brief de minimis pressure differential pulse periods.

4. The method of claim 1, wherein negative pressure differential pulses are delivered using a phacoemulsification handpiece.

5. The method of claim 1, further comprising delivering modulated ultrasonic energy to the ocular region simultaneous with said aspirating.

6. The method of claim 5, wherein timing of modulated ultrasonic energy delivery corresponds to timing of the series of modulated pressure differential pulses.

7. The method of claim 5, wherein timing of modulated ultrasonic energy delivery differs from timing of the series of modulated pressure differential pulses.

8. The method of claim 5, wherein application of modulated ultrasonic energy delivery tends to induce transient cavitation in the ocular region.

9. The method of claim 1, wherein each pressure differential pulse is at most approximately 25 milliseconds.

10. The method of claim 1, wherein each pressure differential pulse is at most approximately eight milliseconds.

11. The method of claim 1, wherein the tubing deformation fluid control device comprises a rotating element configured to deform the tubing at controlled intervals.

12. The method of claim 1, wherein the tubing deformation fluid control device comprises a tubing stretching arrangement configured to stretch the tubing at controlled intervals.

13. The method of claim 1, wherein the tubing deformation fluid control device comprises a linearly translational element configured to deform the tubing at controlled intervals.

14. A method for aspirating fluid from an ocular region, comprising:

applying a series of modulated differential pressure pulses to the ocular region via a tubing deformation fluid control device configured to selectively deform and substantially close aspiration tubing to provide aspirating fluid from the ocular region; and

delivering modulated ultrasonic energy to the ocular region simultaneous with said applying;

wherein selectively deforming and substantially closing aspiration tubing occurs via the tubing deformation fluid control device in a controlled nonrandom manner such that fluid is aspirated according to an alterable and controllable nonrandom timing scheme, and further wherein timing of the series of modulated differential pressure pulses is selectively alterable relative to timing of the modulated ultrasonic energy delivery.

15. The method of claim 14, wherein applying comprises delivering a series of pulses having a negative pressure differential from ambient for duration less than 100 milliseconds.

16. The method of claim 15, wherein said negative pressure differential pulses are interspersed by brief de minimis pressure differential pulse periods.

17. The method of claim 14, wherein negative pressure differential pulses are delivered using a phacoemulsification handpiece.

18. The method of claim 14, further comprising delivering modulated ultrasonic energy to the ocular region simultaneous with said applying.

19. The method of claim 18, wherein timing of modulated ultrasonic energy delivery corresponds to timing of the series of modulated pressure differential pulses.

20. The method of claim 18, wherein timing of modulated ultrasonic energy delivery differs from timing of the series of modulated pressure differential pulses.

21. The method of claim 18, wherein application of modulated ultrasonic energy delivery tends to induce transient cavitation in the ocular region.

22. The method of claim 14, wherein each pressure differential pulse is at most approximately 25 milliseconds.

23. The method of claim 14, wherein each pressure differential pulse is at most approximately eight milliseconds.

24. The method of claim 14, wherein the tubing deformation fluid control device comprises a rotating element configured to deform the tubing at controlled intervals.

25. The method of claim 14, wherein the tubing deformation fluid control device comprises a tubing stretching arrangement configured to stretch the tubing at controlled intervals.

26. The method of claim 14, wherein the tubing deformation fluid control device comprises a linearly translational element configured to deform the tubing at controlled intervals.

27. A method for aspirating fluid from an ocular region, comprising:

applying modulated differential fluid pressure pulses to the ocular region by selectively deforming and substantially closing aspiration tubing, thereby providing aspirating fluid from the ocular region, wherein selectively deforming and substantially closing aspiration tubing occurs in a controlled nonrandom manner such that fluid is aspirated according to an alterable and controllable nonrandom timing scheme; and

delivering modulated ultrasonic energy to the ocular region simultaneous with said applying;

wherein timing of the modulated differential fluid pressure pulses is selectively alterable relative to timing of the modulated ultrasonic energy delivery.

28. The method of claim 27, wherein applying comprises delivering a series of pulses having a negative pressure differential from ambient for duration less than 100 milliseconds.

29. The method of claim 28, wherein said negative pressure differential pulses are interspersed by brief de minimis pressure differential pulse periods.

30. The method of claim 27, wherein negative pressure differential pulses are delivered using a phacoemulsification handpiece.

31. The method of claim 27, wherein timing of modulated ultrasonic energy delivery corresponds to timing of the series of modulated pressure differential pulses.

32. The method of claim 27, wherein timing of modulated ultrasonic energy delivery differs from timing of the series of modulated pressure differential pulses.

33. The method of claim 27, wherein application of modulated ultrasonic energy delivery tends to induce transient cavitation in the ocular region.

34. The method of claim 27, wherein each pressure differential pulse is at most approximately 25 milliseconds.

35. The method of claim 27, wherein each pressure differential pulse is at most approximately eight milliseconds.

36. The method of claim 27, wherein selectively deforming and substantially closing aspiration tubing occurs using a rotating element configured to deform the aspiration tubing at controlled intervals.

37. The method of claim 27, wherein selectively deforming and substantially closing aspiration tubing occurs using a tubing stretching arrangement configured to stretch the aspiration tubing at controlled intervals.

38. The method of claim 27, wherein selectively deforming and substantially closing aspiration tubing occurs using a rotating element configured to deform the aspiration tubing at controlled intervals.

39. A method for treating an ocular region, comprising:

applying modulated differential pressure pulses to the ocular region to aspirate the ocular region by selectively deforming and substantially closing aspiration tubing, thereby providing aspirating fluid from the ocular region, wherein selectively deforming and substantially closing aspiration tubing occurs via the tubing deformation fluid control device in a controlled nonrandom manner such that fluid is aspirated according to an alterable and controllable nonrandom timing scheme; and

delivering modulated ultrasonic energy to the ocular region simultaneous with said applying;

wherein timing of the modulated differential fluid pressure pulses is selectively alterable relative to timing of the modulated ultrasonic energy delivery.

40. The method of claim 39, wherein applying comprises delivering a series of pulses having a negative pressure differential from ambient pressure for a duration of less than 100 milliseconds.

41. The method of claim 40, wherein said negative pressure differential pulses are interspersed by brief de minimis pressure differential pulse periods.

42. The method of claim 40, wherein negative pressure differential pulses are delivered using a phacoemulsification handpiece.

43. The method of claim 39, wherein timing of modulated ultrasonic energy delivery corresponds to timing of the series of modulated pressure differential pulses.

44. The method of claim 39, wherein timing of modulated ultrasonic energy delivery differs from timing of the series of modulated pressure differential pulses.

45. The method of claim 39, wherein applying modulated ultrasonic energy delivery tends to induce transient cavitation in the ocular region.

46. The method of claim 39, wherein each pressure differential pulse is at most approximately 25 milliseconds.

47. The method of claim 39, wherein each pressure differential pulse is at most approximately eight milliseconds.

48. The method of claim 39, wherein selectively deforming and substantially closing aspiration tubing occurs using a rotating element configured to deform the aspiration tubing at controlled intervals.

49. The method of claim 39, wherein selectively deforming and substantially closing aspiration tubing occurs using a tubing stretching arrangement configured to stretch the aspiration tubing at controlled intervals.

50. The method of claim 39, wherein selectively deforming and substantially closing aspiration tubing occurs using a rotating element configured to deform the aspiration tubing at controlled intervals.

51. A method for aspirating fluid during a phacoemulsification procedure, comprising:

applying a series of modulated differential fluid pressure pulses to an ocular region during the phacoemulsification procedure by selectively deforming and substantially closing aspiration tubing, thereby providing aspirating fluid from the ocular region; and

delivering modulated ultrasonic energy to the ocular region simultaneous with said applying;

wherein selectively deforming and substantially closing aspiration tubing occurs in a controlled nonrandom manner such that fluid is aspirated according to an alterable and controllable nonrandom timing scheme;

wherein timing of the modulated differential fluid pressure pulses is selectively alterable relative to timing of the modulated ultrasonic energy delivery.

52. The method of claim 51, wherein said applying occurs using a fluid control device.

53. The method of claim 51, wherein applying comprises delivering a series of pulses having a negative pressure differential from ambient.

54. The method of claim 53, wherein delivering the series of pulses having the negative pressure differential for a series of durations of less than 100 milliseconds.

55. The method of claim 54, wherein said negative pressure differential pulses are interspersed by brief de minimis pressure differential pulse periods.

56. The method of claim 52, wherein negative pressure differential pulses are delivered using a phacoemulsification handpiece.

57. The method of claim 51, further comprising delivering modulated ultrasonic energy to the ocular region simultaneous with said aspirating.

58. The method of claim 57, wherein timing of modulated ultrasonic energy delivery corresponds to timing of the series of modulated pressure differential pulses.

59. The method of claim 57, wherein timing of modulated ultrasonic energy delivery differs from timing of the series of modulated pressure differential pulses.

60. The method of claim 57, wherein application of modulated ultrasonic energy delivery tends to induce transient cavitation in the ocular region.

61. The method of claim 53, wherein each pressure differential pulse is at most approximately 25 milliseconds.

62. The method of claim 53, wherein each pressure differential pulse is at most approximately eight milliseconds.

63. The method of claim 51, wherein selectively deforming and substantially closing aspiration tubing occurs using a rotating element configured to deform the aspiration tubing at controlled intervals.

64. The method of claim 51, wherein selectively deforming and substantially closing aspiration tubing occurs using a tubing stretching arrangement configured to stretch the aspiration tubing at controlled intervals.

65. The method of claim 51, wherein selectively deforming and substantially closing aspiration tubing occurs using a rotating element configured to deform the aspiration tubing at controlled intervals.