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Method and device for ultrasonically manipulating particles within a fluid

  • US 7,846,382 B2
  • Filed: 06/03/2003
  • Issued: 12/07/2010
  • Est. Priority Date: 06/04/2002
  • Status: Expired due to Fees
First Claim
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1. A fluid-handling device for ultrasonic manipulation of fluid-borne particles, comprising, in combination:

  • a fluid-handling manifold having a fluid inlet port and defining a fluid-handling void comprising at least a first fluid channel;

    a second fluid channel in fluid communication with the first fluid channel at an intersection within the ultrasonic cavity; and

    an ultrasonic particle manipulator defining an ultrasonic cavity and comprising at least one ultrasonic transducer, the first fluid channel extending from the inlet port to the ultrasonic cavity and the ultrasonic particle manipulator being operative to establish an ultrasonic standing wave field in particle-bearing fluid in the first fluid channel at the ultrasonic cavity,wherein the ultrasonic cavity has a non-uniform configuration;

    wherein the first fluid channel and the second fluid channel extend substantially parallel each other on opposite sides of a dividing wall between them, andwherein the intersection comprises a passageway through the dividing wall.

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