Device for delivering medicines by transpalpebral electrophoresis
First Claim
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1. A device for ocular application of an active substance comprising a main electrode, the main electrode comprising:
- (i) an insulating layer,(ii) a conductive layer,(iii) an electric lead sandwiched between the insulating layer and the conductive layer, wherein the electric lead is configured for connecting the main electrode to an external electrical feeding source,(iv) an adhesive interlayer comprising material having adhesive properties for bonding the insulating layer to the conductive layer and for holding the electric lead onto the conductive layer, and(v) a foam layer bonded to the conductive layer by a conductive adhesive layer, wherein the foam layer is an absorbent foam layer able to act as a reservoir for the active substance,wherein the main electrode comprises a functional area configured to substantially cover an outer surface of an eyelid and which delivers the active substance through the eyelid onto the sclera of the eyeball and a non-functional central area.
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Abstract
The invention concerns a device for ocular application of an active principle (1) comprising a main electrode (2) including an insulating layer, an adhesive layer designed to bind the insulating layer to a conductive layer, characterized in that the main electrode comprises a zone (21, 22) designed to be urged into contact with an eyelid.
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Citations
15 Claims
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1. A device for ocular application of an active substance comprising a main electrode, the main electrode comprising:
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(i) an insulating layer, (ii) a conductive layer, (iii) an electric lead sandwiched between the insulating layer and the conductive layer, wherein the electric lead is configured for connecting the main electrode to an external electrical feeding source, (iv) an adhesive interlayer comprising material having adhesive properties for bonding the insulating layer to the conductive layer and for holding the electric lead onto the conductive layer, and (v) a foam layer bonded to the conductive layer by a conductive adhesive layer, wherein the foam layer is an absorbent foam layer able to act as a reservoir for the active substance, wherein the main electrode comprises a functional area configured to substantially cover an outer surface of an eyelid and which delivers the active substance through the eyelid onto the sclera of the eyeball and a non-functional central area. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. An electrode for the ocular application of an active substance comprising a main electrode, the main electrode comprising:
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(i) an insulating layer, (ii) a conductive layer, (iii) an electric lead sandwiched between the insulating layer and the conductive layer, connecting the main electrode to an external electrical feeding source, (iv) an adhesive interlayer comprising material having adhesive properties for bonding the insulating layer to the conductive layer and for holding the electric lead onto the conductive layer, (v) a foam layer, wherein the foam layer is an absorbent foam layer able to act as a reservoir for the active substance, (vi) a conductive adhesive layer sandwiched between the foam layer and the conductive layer, comprising water insoluble material having adhesive properties for bonding the foam layer to the conductive layer, and (vii) a cutaneous adhesive layer adjacent to the foam layer and having adhesive properties for bonding the main electrode to the outer surface of the eyelid, wherein the electrode comprises a functional area configured to substantially cover an outer surface of an eyelid and which delivers the active substance through the eyelid onto the sclera of the eyeball and a non functional central core.
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Specification