Cardiac force sensor and methods of use

• US 7,848,822 B2
• Filed: 11/14/2006
• Issued: 12/07/2010
• Est. Priority Date: 11/14/2006
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Zhang, Yongxing, Wei, Xuan, Zhang, Yunlong
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Stice; Paula J
• Application Number:
  US11/559,702
• Publication Number:
  US 20080114256A1
• Time in Patent Office: 1,484 Days
• Field of Search: 607/6, 607/36, 607 16- 20, 607115-117, 600514-518, 600/508
• US Class Current: 607/122
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/224 Measuring muscular strength
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/6846 specially adapted to be brought in contact with an internal body part, i.e. invasive
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61B 5/6869 Heart
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy

Abstract

A method and apparatus permit sensing one or more forces exerted by one or more portions of a heart. A force transducer and displacement sensor are disclosed. A movement of one or more portions of a heart can be translated into one or more signals indicative of force. These signals can be used to provide information such as to diagnose or treat one or more conditions.

Claims

1. An apparatus, comprising:

a fully implantable intravascular cardiac lead including a proximal portion and a distal portion, the proximal portion adapted to be coupled to an electronics unit of an implantable medical device, the distal portion adapted to be located within a chamber of a heart; and

a force sensor associated with the distal portion of the fully implantable intravascular cardiac lead, the force sensor including;

a displacement sensor adapted to sense a displacement of a portion of the heart during a heart movement, the displacement sensor including a first portion movable with respect to a second portion along an axial direction of the lead and in response to the displacement of the portion of the heart, axial movement of the first portion with respect to the second portion being representative of the displacement of the portion of the heart, the displacement sensor being configured to provide an output displacement signal indicative of the displacement sensed; and

a contractile structure separate from the displacement sensor, the contractile structure being configured to axially expand or axially contract an axial distance representative of the axial movement of the first portion of the displacement sensor with respect to the second portion, wherein the force sensor is configured to provide a sensed force signal indicative of a force with which at least the portion of the heart moves during the heart movement, the force sensor configured to determine the force as a function of the distance that the contractile structure axially expands or axially contracts, the force sensor being configured to communicate the sensed force signal to the electronics unit.

2. The apparatus of claim 1, comprising a fixation structure, associated with the distal portion of the lead and adapted to be secured to a portion of the heart, and wherein the fixation structure is associated with the displacement sensor.

3. The apparatus of claim 1, in which the contractile structure includes a spring.

4. The apparatus of claim 1, in which the contractile structure includes a bellows.

5. The apparatus of claim 1, in which the contractile structure includes a specified force-displacement relationship, and further comprising an electronics unit of the implantable medical device, the electronics unit adapted to determine, in accordance to the relationship, the force with which the at least one portion of the heart moves.

6. The apparatus of claim 5, in which the electronics unit is adapted to determine the pressure of the at least one portion of the heart using the force.

7. The apparatus of claim 1, comprising an electronics unit adapted to determine, at least one of an acceleration, a velocity, and a displacement of the at least one portion of the heart.

8. The apparatus of claim 1, in which the lead includes at least one electrode adapted to sense an intrinsic electric heart signal or to deliver electric energy to the heart.

9. The apparatus of claim 1, wherein the electronics unit of the implantable medical device includes a controller adapted to initiate or adjust a delivered electrical energy or a delivered substance in response to the sensed force signal.

10. The apparatus of claim 1, comprising:

an electronics unit, adapted to use one or more sensed forces to determine at least one of;

a ventricular uptake;

a ventricular relaxation behavior;

an interventricular mechanical delay;

an interventricular dyssynchrony;

a ventricular output;

an electromechanical delay;

an evoked response;

a pacing voltage;

a pacing location;

a paradoxical movement; and

a respiratory signal.

11. The apparatus of claim 1, wherein the first portion of the displacement sensor includes a core and the second portion of the displacement sensor includes a lumen, the core being movable within the lumen in response to the displacement of the portion of the heart.

12. An apparatus comprising:

a fully implantable intravascular cardiac lead including a proximal portion and a distal portion, the proximal portion configured to be coupled to an electronics unit of an implantable medical device, the distal portion configured to be located within a chamber of a heart; and

a force sensor associated with the distal portion of the fully implantable intravascular lead, the force sensor including;

a displacement sensor configured to sense a displacement of a portion of the heart during a heart movement, the displacement sensor including a first portion movable with respect to a second portion along an axial direction of the lead and in response to the displacement of the portion of the heart, axial movement of the first portion with respect to the second portion being representative of the displacement of the portion of the heart, the displacement sensor being configured to provide an output displacement signal indicative of the displacement sensed; and

a spring disposed at least partially around the displacement sensor, the spring configured to axially expand or axially contract an axial distance representative of the axial movement of the first portion of the displacement sensor with respect to the second portion, wherein the force sensor is configured to provide a sensed force signal indicative of a force with which at least the portion of the heart moves during the heart movement, the force sensor configured to determine the force as a function of the distance that the spring axially expands or axially contracts, the force sensor being configured to communicate the sensed force signal to the electronics unit.

13. The apparatus of claim 12, comprising a fixation structure associated with the distal portion of the lead and configured to be secured to a portion of the heart, and wherein the fixation structure is associated with the displacement sensor.

14. The apparatus of claim 12, in which the spring includes a specified force-displacement relationship, and further comprising an electronics unit of the implantable medical device, the electronics unit adapted to determine, in accordance to the relationship, the force with which the at least one portion of the heart moves.

15. The apparatus of claim 12, comprising an electronics unit adapted to determine at least one of an acceleration, a velocity, and a displacement of the at least one portion of the heart.

16. The apparatus of claim 15, in which the electronics unit is configured to determine the pressure of the at least one portion of the heart using the force.

17. The apparatus of claim 12, in which the lead includes at least one electrode adapted to sense an intrinsic electric heart signal or to deliver electric energy to the heart.

18. The apparatus of claim 12, wherein the electronics unit of the implantable medical device includes a controller adapted to initiate or adjust a delivered electrical energy or a delivered substance in response to the sensed force signal.

19. The apparatus of claim 12, comprising an electronics unit configured to use one or more sensed forces to determine a paradoxical movement of the heart.

20. The apparatus of claim 12, comprising an electronics unit configured to use one or more sensed forces to determine a ventricular uptake of the heart.

21. The apparatus of claim 12, comprising an electronics unit configured to use one or more sensed forces to determine a ventricular relaxation behavior of the heart.

22. The apparatus of claim 12, comprising an electronics unit configured to use one or more sensed forces to determine a pacing location of the heart.

23. The apparatus of claim 12, comprising an electronics unit configured to use one or more sensed forces to determine a respiratory signal of the heart.

24. The apparatus of claim 12, wherein the first portion of the displacement sensor includes a core and the second portion of the displacement sensor includes a lumen, the core being movable within the lumen in response to the displacement of the portion of the heart.

25. An apparatus comprising:

a fully implantable intravascular cardiac lead including a proximal portion and a distal portion, the proximal portion configured to be coupled to an electronics unit of an implantable medical device, the distal portion configured to be located within a chamber of a heart; and

a force sensor associated with the distal portion of the fully implantable intravascular lead, the force sensor including;

a displacement sensor configured to sense a displacement of a portion of the heart during a heart movement, the displacement sensor including a first portion movable with respect to a second portion along an axial direction of the lead and in response to the displacement of the portion of the heart, axial movement of the first portion with respect to the second portion being representative of the displacement of the portion of the heart, the displacement sensor being configured to provide an output displacement signal indicative of the displacement sensed; and

a bellows disposed at least partially around the displacement sensor, the bellows configured to axially expand or axially contract an axial distance representative of the axial movement of the first portion of the displacement sensor with respect to the second portion, wherein the force sensor is configured to provide a sensed force signal indicative of a force with which at least the portion of the heart moves during the heart movement, the force sensor configured to determine the force as a function of the distance that the bellows axially expands or axially contracts, the force sensor being configured to communicate the sensed force signal to the electronics unit.

26. The apparatus of claim 25, comprising a fixation structure associated with the distal portion of the lead and configured to be secured to a portion of the heart, and wherein the fixation structure is associated with the displacement sensor.

27. The apparatus of claim 25, in which the bellows includes a specified force-displacement relationship, and further comprising an electronics unit of the implantable medical device, the electronics unit adapted to determine, in accordance to the relationship, the force with which the at least one portion of the heart moves.

28. The apparatus of claim 25, comprising an electronics unit adapted to determine at least one of an acceleration, a velocity, and a displacement of the at least one portion of the heart.

29. The apparatus of claim 28, in which the electronics unit is configured to determine the pressure of the at least one portion of the heart using the force.

30. The apparatus of claim 25, in which the lead includes at least one electrode adapted to sense an intrinsic electric heart signal or to deliver electric energy to the heart.

31. The apparatus of claim 25, wherein the electronics unit of the implantable medical device includes a controller adapted to initiate or adjust a delivered electrical energy or a delivered substance in response to the sensed force signal.

32. The apparatus of claim 25, comprising an electronics unit configured to use one or more sensed forces to determine a paradoxical movement of the heart.

33. The apparatus of claim 25, comprising an electronics unit configured to use one or more sensed forces to determine a ventricular output of the heart.

34. The apparatus of claim 25, comprising an electronics unit configured to use one or more sensed forces to determine an interventricular mechanical delay of the heart.

35. The apparatus of claim 25, comprising an electronics unit configured to use one or more sensed forces to determine an interventricular dyssynchrony of the heart.

36. The apparatus of claim 25, comprising an electronics unit configured to use one or more sensed forces to determine an evoked response of the heart.

37. The apparatus of claim 25, wherein the first portion of the displacement sensor includes a core and the second portion of the displacement sensor includes a lumen, the core being movable within the lumen in response to the displacement of the portion of the heart.