Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
First Claim
1. A method for treating an anxiety disorder in a patient comprising administering to the patient a pharmaceutical composition comprising i) pipamperone in a dose of 5-15 mg and ii) citalopram in a dose of 10-40 mg.
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Abstract
The present invention relates to methods of treating of the underlying dysregulation of the emotional functionality of mental disorders (i.e. affect instability-hypersensitivity-hyperaesthesia-dissociative phenomena- . . . ) using compounds and compositions of compounds having D4 and/or 5-HT2A antagonistic, partial agonistic or inverse agonistic activity for. The invention also relates to methods comprising administering to a patient diagnosed as having a neuropsychiatric disorder a pharmaceutical composition containing (i) compounds having D4 antagonistic, partial agonistic or inverse agonistic activity and/or (ii) compounds having 5-HT2A antagonistic, partial agonistic or inverse agonistic, and/or (iii) any known medicinal compound and compositions of said compounds. The combined D4 and 5-HT2A antagonistic, partial agonistic or inverse agonistic effects may reside within the same chemical or biological compound or in two different chemical and/or biological compounds.
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17 Claims
- 1. A method for treating an anxiety disorder in a patient comprising administering to the patient a pharmaceutical composition comprising i) pipamperone in a dose of 5-15 mg and ii) citalopram in a dose of 10-40 mg.
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