Systems and methods for patient interactive neural stimulation and/or chemical substance delivery

• US 7,856,264 B2
• Filed: 10/19/2005
• Issued: 12/21/2010
• Est. Priority Date: 10/19/2005
• Status: Expired due to Fees

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Inventors: Firlik, Andrew D., Sheffield, W. Douglas, Gliner, Bradford Evan, Sloan, Leif R.
• Primary Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US11/255,187
• Publication Number:
  US 20070179534A1
• Time in Patent Office: 1,889 Days
• Field of Search: None
• US Class Current: 607/3
• CPC Class Codes: A61B 5/16 Devices for psychotechnics using teaching or educational appliances G09B1/00 - G09B7/00; Testing reaction times ; Devices for evaluating the psychological state
• CPC Class Codes: A61B 5/18 for vehicle drivers or machine operators
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61F 2002/704 computer-controlled, e.g. robotic control
• CPC Class Codes: A61M 2205/05 combined with other kinds of therapy
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2230/63 Motion, e.g. physical activity
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/361 Phantom sensations, e.g. tinnitus
• CPC Class Codes: A61N 1/36103 Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
• CPC Class Codes: A61N 1/36139 with automatic adjustment
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 20/70 : relating to mental therapies, e.g. psychological therapy or autogenous training

Abstract

Systems and methods for patient interactive neural stimulation and/or chemical substance delivery are disclosed. A method in accordance with one embodiment of the invention includes affecting a target neural population of the patient by providing to the patient at least one of an electromagnetic signal and a chemical substance. The method can further include detecting at least one characteristic of the patient, with the characteristic at least correlated with the patient'"'"'s performance of an adjunctive therapy task that is performed in association with affecting the target neural population. The method can still further include controlling at least one parameter in accordance with which the target neural population is affected, based at least in part on the detected characteristic.

Claims

1. A system for treating a patient, comprising:

an adjunctive therapy device;

a patient treatment delivery device that includes an implantable drug delivery device or a combination of an electromagnetic stimulator and an implantable drug delivery device;

a control system operatively coupled to the adjunctive therapy device and the patient treatment device, the control system including a computer-readable medium having instructions for;

automatically receiving information from the adjunctive therapy device, the information being correlated with the patient'"'"'s performance of a task at the adjunctive therapy device; and

based at least in part on the information received from the adjunctive therapy device, automatically controlling a parameter in accordance with which the patient treatment delivery device provides treatment to the patient.

2. The system of claim 1 wherein the control system has instructions for automatically controlling a parameter in an at least approximately real time manner relative to receiving information from the adjunctive therapy device.

3. The system of claim 1 wherein the patient treatment device includes an implantable electrode and pulse generator.

4. The system of claim 1 wherein the adjunctive therapy device includes a patient actuatable element and a feedback sensor, the feedback sensor being coupled to the control system to direct to the control system at least one signal corresponding to the patient'"'"'s manipulation of the actuatable element.

5. The system of claim 4 wherein the feedback sensor is configured to detect a motion of the patient.

6. The system of claim 1 wherein the adjunctive therapy device includes at least one robotic element.

7. The system of claim 6 wherein the at least one robotic element is positioned to resist patient movement under direction of the control system.

8. The system of claim 6 wherein the at least one robotic element is positioned to assist patient movement under direction of the control system.

9. The system of claim 1 wherein at least one of the adjunctive therapy device and the control system includes a patient-interactive computer system.

10. The system of claim 9 wherein at least one of the adjunctive therapy device and the control system includes a virtual reality system.

11. The system of claim 1 wherein the patient treatment delivery device includes a deep brain stimulation device.

12. The system of claim 1 wherein the patient treatment delivery device includes a spinal column stimulation device.

13. The system of claim 1 wherein the patient treatment delivery device includes a transcranial direct current stimulation device.

14. The system of claim 1 wherein the patient treatment delivery device includes a transcranial magnetic stimulation device.

15. The system of claim 1 wherein the patient treatment delivery device includes a cortical stimulation device.

16. The system of claim 1 wherein the patient treatment delivery device includes a peripheral nerve stimulation device.

17. The system of claim 1 wherein the adjunctive therapy device is configured to deliver at least one of a proprioceptive, electrical, visual and auditory stimulus to the patient.