Monoclonal antibodies that selectively recognize methamphetamine and methamphetamine like compounds
First Claim
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1. An isolated monoclonal antibody that recognizes each compound of the group consisting of (+)amphetamine, (+)methamphetamine, and (+)3,4-methylenedioxymethamphetamine, and does not substantially recognize each compound of the group consisting of (−
- )amphetamine, (−
)methamphetamine, and (−
)3,4-methylenedioxymethamphetamine, wherein the antibody is generated using a immunizing agent comprising the formula
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Abstract
The invention generally relates to monoclonal antibodies that recognize at least one compound from the group consisting of (+) methamphetamine, (+) amphetamine, and (+) 3,4-methylenedioxymethamphetamine ((+) MDMA). Generally speaking, the monoclonal antibodies do not recognize (−) methamphetamine, (−) amphetamine, or (−) MDMA.
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Citations
17 Claims
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1. An isolated monoclonal antibody that recognizes each compound of the group consisting of (+)amphetamine, (+)methamphetamine, and (+)3,4-methylenedioxymethamphetamine, and does not substantially recognize each compound of the group consisting of (−
- )amphetamine, (−
)methamphetamine, and (−
)3,4-methylenedioxymethamphetamine, wherein the antibody is generated using a immunizing agent comprising the formula - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- )amphetamine, (−
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17. A kit, wherein the kit comprises a monoclonal antibody that recognizes each compound of the group consisting of (+)amphetamine, (+)methamphetamine, and (+)3,4-methylenedioxymethamphetamine, and does not substantially recognize each compound of the group consisting of (−
- )amphetamine, (−
) methamphetamine, and (−
)3,4-methylenedioxymethamphetamine, wherein the antibody is generated using a immunizing agent comprising the formula
- )amphetamine, (−
Specification